Letter to the glyco-forum: Catalytic domains of glycosyltransferases with 'add-on' domains

Glycobiology

Volumn 17, Issue 5, 2007, Pages

  Qasba, Pradman K ^a   Ramakrishnan, Boopathy ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1,6 FUCOSYLTRANSFERASE; ALPHA LACTALBUMIN; BETA N ACETYLGLUCOSAMINYLGLYCOPEPTIDE BETA 1,4 GALACTOSYLTRANSFERASE; EPIDERMAL GROWTH FACTOR RECEPTOR; FUCOSYLTRANSFERASE; GLYCOSYLTRANSFERASE; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G1; N ACETYLGALACTOSAMINYLTRANSFERASE; PROTEIN SH3; PROTEIN TYROSINE KINASE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; BETA SHEET; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; FUCOSYLATION; HUMAN; LETTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DATABASE; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION;

ANIMALS; CATALYTIC DOMAIN; DATABASES, PROTEIN; GLYCOLIPIDS; GLYCOPROTEINS; GLYCOSYLATION; GLYCOSYLTRANSFERASES; GOLGI APPARATUS; HUMANS; OLIGOSACCHARIDES; PROTEIN MODIFICATION, TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY;

EID: 34447305187     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwm013     Document Type: Letter

References (15)

1. Fritz T, Raman J, Tabak LA. 2006. Dynamic association between the catalytic and lectin domains of human UDP-GalNAc:pOlypeptide α-N acetylgalactosaminyltransferase-2. J Biol Chem. 281: 8613-8619.
2. Gotoh M, Sato T, Kiyohara K, Kameyama A, Kikuchi N, Kwon YD, Ishizuka Y, Iwai T, Nakanishi H, Narimatsu H. 2004. Molecular cloning and characterization of β1, 4-N-acetyl-galactosaminyltransferases IV synthesizing N, N'-diacetyllactosediamine. FEBS Lett. 562:134-140.
3. Huse M, Kuriyan J. 2002. The conformational plasticity of protein kinases. Cell. 109:275-282.
4. Ihara H, Ikeda Y, Toma S, Wang X, Suzuki T, Gu J, Miyoshi E, Tsukihara T, Honke K, Matsumoto A et al. 2007. Crystal structure of mammalian α1,6-fucosyltransferase, FUT8. Glycobiology. 17:455-466.
5. Javaud C, Dupuy F, Maftah A, Michalski J, Oriol R, Petit J, Julien R. 2000. Ancestral exonic organization of FTU8, the gene encoding the α6-fucosyltransferase, reveals successive peptide domains which suggest a particular three-dimensional core structure for the α6-fucosyltransferase family. Mol Biol Evol. 17:1661-1672.
6. Kubota T, Shiba T, Sugioka S, Furukawa S, Sawaki H, Kato R, Wakatsuki S, Natimatsu H. 2006. Structural basis of carbohydrate transfer activity by human UDP-GalNAc:pOlypeptide α-N-acetylgalactosaminyltransferase (pp-GalNAc-T10). J Mol Biol. 359:708-727.
7. Li SS-C. 2005. Specificity and versatility of SH3 and other proline-recognition domains: Structural basis and implications for cellular signal transduction. Biochem J. 390:641-653.
8. Lu W, Leimkuhlar C, Gatto GJ, Kruger RG, Oberthur M, Kahne D, Walsh TC. 2005. AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycon of aclacinomycin A. Chem Biol. 12:527-534.
9. Qasba PK, Ramakrishnan B, Boeggeman E. 2005. Substrate induced conformational changes in glycosyltransferases. Trends Biochem Sci. 30: 53-62.
10. Radha Kishan KV, Agrawal V. 2005. SH3-like fold proteins are structurally conserved and functionally divergent. Curr Protein Pept Sci. 6:143-150.
11. Ramakrishnan B, Boeggeman E, Qasba PK. 2002. β1-4-Galactosyltransferase and lactose synthase: Molecular mechanical devices. Biochem Biophys Res Commun. 291:1113-1118.
12. Ramakrishnan B, Boeggeman E, Ramasamy V, Qasba PK. 2004. Structure and catalytic cycle of beta-1,4-galactosyltransferase. Curr Opin Struct Biol. 14: 593-600.
13. Ramakrishnan B, Qasba PK. 2001. Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the β1-4-galactosyltransferase-I. J Mol Biol. 310:205-218.
14. Ramakrishnan B, Qasba PK. 2007. Role of a single amino acid in the evolution of glycans of invertebrates and vertebrates. J Mol Biol. 365:570-576.
15. Wang X, Gu J, Ihara H, Miyoshi E, Honke K, Taniguchi N. 2006. Core fucosylation regulates epidermal growth factor receptor-mediated intracellular signaling. J Biol Chem. 281:2572-2577.