Synthesis of novel antitumoural analogues of dysidiolide from ent-halimic acid

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 17, 2007, Pages 5719-5737

  Marcos, I S ^a   Escola, M A ^a   Moro, R F ^a   Basabe, P ^a   Diez, D ^a   Sanz, F ^a   Mollinedo, F ^a   de la Iglesia Vicente, J ^a   Sierra, B G ^a   Urones, J G ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Antitumour activity; Dysidiolide analogues; ent Halimic acid; Sesterterpenolides

Indexed keywords

4 ACETOXY 25 HYDROXY 18 NOR ENT ISODYSIDIOLA 2,9,19 TRIEN 1,25 OLIDE; 4 ACETOXY 25 HYDROXY ENT ISODYSIDIOLA 2,9,19 TRIEN 1,25 OLIDE; 4,25 DIHYDROXY 18 NOR ENT ISODYSIDIOLA 2,9,19 TRIEN 1,25 OLIDE; 4,25 DIHYDROXY 4,9 CYCLO 2,10,19 ENT ISODYSIDIOLA 2,10,19 TRIEN 1,25 OLIDE; 4,25 DIHYDROXY ENT ISODYSIDIOLA 2,9,19 TRIEN 1,25 OLIDE; BUTENOLIDE; DYSIDIOLIDE DERIVATIVE; ENT HALIMIC ACID DERIVATIVE; SESTERTERPENE; SESTERTERPENOLIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50;

4-BUTYROLACTONE; ALDEHYDES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; HYDROXYLATION; KETONES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES;

EID: 34447296207     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.06.007     Document Type: Article

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