The protective effect of circumcision on HIV incidence in rural low-risk men circumcised predominantly by traditional circumcisers in Kenya: Two-year follow-up of the Kericho HIV Cohort Study

Journal of Acquired Immune Deficiency Syndromes

Volumn 45, Issue 4, 2007, Pages 371-379

  Shaffer, Douglas N ^a,g   Bautista, Christian T ^b   Sateren, Warren B ^c   Sawe, Frederick K ^d   Kiplangat, Stanley C ^d   Miruka, Argwings O ^d   Renzullo, Philip O ^e   Scott, Paul T ^c   Robb, Merlin L ^b   Michael, Nelson L ^c   Birx, Deborah L ^c,f  

^a US Army Medical Research Unit   (Kenya)

^b HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE   (United States)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^d KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^g US Army Medical Research Unit Kenya   (Kenya)

Author keywords

Circumcision; HIV; Kenya; Low risk; Male; Rural

Indexed keywords

ADULT; ARTICLE; CIRCUMCISION; CONFIDENCE INTERVAL; CONTROLLED STUDY; CULTURAL FACTOR; DEMOGRAPHY; EDUCATIONAL STATUS; FOLLOW UP; HAZARD RATIO; HEALTH CARE POLICY; HIGH RISK BEHAVIOR; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; INFECTION RISK; KENYA; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RURAL POPULATION; SOCIAL ASPECT;

ADOLESCENT; ADULT; CHILD; CIRCUMCISION, MALE; COHORT STUDIES; HIV INFECTIONS; HIV-1; HUMANS; INCIDENCE; KENYA; MALE; MEDICINE, AFRICAN TRADITIONAL; RISK FACTORS; RURAL POPULATION; SEXUAL BEHAVIOR;

EID: 34447295410     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e318095a3da     Document Type: Article

References (22)

1. National Institute of Allergy and Infectious Diseases, U.S. National Institutes of Health. Adult male circumcision significantly reduces risk of acquiring HIV. Trials Kenya and Uganda stopped early. Available at: http://www3.niaid.nih.gov/news/newsreleases/2006/AMC12_06.htm. Accessed January 7, 2006.
2. Bailey R, Moses S, Agot K, et al. A randomized controlled trial of male circumcision to reduce HIV incidence in Kisumu, Kenya: progress to date. Presented at: XVI International AIDS Conference; 2006; Toronto.
3. Sateren W, Bautista C, Shaffer D, et al. Male circumcision and HIV infection risk among tea plantation residents in Kericho, Kenya: incidence results after 1.5 years of follow-up. Presented at: XVI International AIDS Conference; 2006; Toronto.
4. Mesesan K, Owens D, Paltiel A. The potential benefits of expanded male circumcision programs in Africa: predicting the population-level impact on heterosexual HIV transmission in Soweto. Presented at: XVI International AIDS Conference; 2006; Toronto.
5. Kahn J, Marseille E, Aubert B. Cost-effectiveness of male circumcision in sub-Saharan Africa. Presented at: XVI International AIDS Conference; 2006; Toronto.
6. Agot K, Kiarie J, Nguyen H, et al. Male circumcision in Siaya and Bondo districts, Kenya: a prospective cohort study to assess behavioural disinhibition following circumcision. Presented at: XVI International AIDS Conference; 2006; Toronto.
7. Auvert B, Taljaard D, Lagarde E, et al. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 trial. PLoS Medicine. 2005;2:1112-1122.
8. Bailey R, Moses S, Parker C, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. 2007;369:643-656.
9. Gray R, Kigozi G, Serwadda D, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet. 2007;369:657-666.
10. National AIDS and STI Control Programme, Ministry of Health, Kenya. AIDS in Kenya. 7th ed. Nairobi, Kenya: NASCOP; 2005.
11. Foglia G, Royster G, Wasunna K, et al. Use of rapid and conventional testing technologies for human immunodeficiency virus type 1 serologic screening in a rural Kenyan reference laboratory. J Clin Microbiol. 2004;42:3850-3852.
12. Lavreys L, Rakwar J, Thompson M, et al. Effect of circumcision on incidence of Human Immunodeficiency Virus type 1 and other sexually transmitted diseases: a prospective cohort study of trucking company employees in Kenya. J Infect Dis. 1999;180:330-336.
13. Beaten J, Richardson B, Lavreys L, et al. Female-to-male infectivity of HIV-1 among circumcised and uncircumcised Kenyan men. J Infect Dis. 2005;191:546-553.
14. Gray R, Kiwanuka N, Quinn T, et al. Male circumcision and HIV acquisition and transmission: cohort studies in Rakia, Uganda. Rakai Project Team. AIDS. 2000;14:2372-2381.
15. Quinn T, Wawer M, Sewankambo N, et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. N Engl J Med. 2000;342:921-929.
16. Bailey R, Muga R, Poulussen R, et al. The acceptability of male circumcision to reduce HIV infections in Nyanza Province, Kenya. AIDS Care. 2002;14:27-40.
17. Luginaah I, Elkins D, Maticka-Tyndale E, et al. Challenges of a pandemic: HIV/AIDS-related problems affecting Kenyan widows. Soc Sci Med. 2005;60:1219-1228.
18. Westercamp N, Bailey R. Acceptabiligy of male circumcision for prevention of HIV/AIDS in sub-Saharan Africa: a review. AIDS Behav. 2007;11:341-355.
19. Krieger J, Bailey R, Opeya J, et al. Adult male circumcision: results of a standardized procedure in Kisumu District, Kenya. BJU Int. 2005;96:1009-1013.
20. Cameron D, Simonsen J, D'Costa L, et al. Female to male transmission of human immunodeficiency virus type 1: risk factors for seroconversion in men. Lancet. 1989;2:403-407.
21. Reynolds S, Shepherd M, Risbud A, et al. Male circumcision and risk for HIV-1 and other sexually transmitted infections in India. Lancet. 2004;363:1039-1040.
22. Weiss H, Quigley M, Hayes R. Male circumcision and risk of HIV infection in sub-Saharan Africa: a systematic review and meta-analysis. AIDS. 2000;14:2361-2370.