Pediatric-Onset Gelastic Seizures: Clinical Data and Outcome

Pediatric Neurology

Volumn 37, Issue 1, 2007, Pages 29-34

  Shahar, Eli ^a,f   Kramer, Uri ^b,f   Mahajnah, Muhammad ^c,f   Lerman Sagie, Tallie ^d,f   Goez, Rachel ^e,f   Gross, Varda ^d,f   Kutai, Miriam ^f,g   Genizi, Jacob ^a,f  

^a MEYER CHILDREN S HOSPITAL   (Israel)

^b Dana Children's Hospital   (Israel)

^c CARMEL MEDICAL CENTER   (Israel)

^d WOLFSON MEDICAL CENTER   (Israel)

^e Child Developmental Center   (Israel)

^f Sha'arei Zedek Medical Center   (Israel)

^g HAEMEK MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CLOZAPINE; ETIRACETAM; LAMOTRIGINE; STEROID; VALPROIC ACID;

ADOLESCENT; ARTICLE; BRAIN CORTEX; BRAIN RADIOGRAPHY; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; DISEASE CONTROL; ELECTROENCEPHALOGRAM; FEMALE; GELASTIC SEIZURE; HAMARTOMA; HEALTH SURVEY; HUMAN; HYPOTHALAMUS; ISRAEL; KETOGENIC DIET; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PRIORITY JOURNAL; RECURRENT DISEASE; SYMPTOMATOLOGY; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT RESPONSE;

AGE OF ONSET; ANTICONVULSANTS; BRAIN DISEASES; CHILD; CHILD, PRESCHOOL; ELECTROENCEPHALOGRAPHY; EPILEPSIES, PARTIAL; FEMALE; HAMARTOMA; HUMANS; HYPOTHALAMUS; INFANT; INFANT, NEWBORN; ISRAEL; MAGNETIC RESONANCE IMAGING; MALE; NEUROSURGICAL PROCEDURES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 34447292531     PISSN: 08878994     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pediatrneurol.2007.03.003     Document Type: Article

References (26)

1. Gascon G.G., and Lombroso C.T. Epileptic (gelastic) laughter. Epilepsia 12 (1971) 63-76
2. Loiseau P., Cohadon F., and Cohadon S. Gelastic epilepsy: a review and report of five cases. Epilepsia 12 (1971) 313-323
3. Arroyo S., Lesser R.P., Gordon B., et al. Mirth, laughter and gelastic seizures. Brain 116 (1993) 757-780
4. Striano S., Meo R., Bilo L., et al. Gelastic epilepsy: symptomatic and cryptogenic cases. Epilepsia 40 (1999) 294-302
5. Brandberg G., Raininko R., and Eeg-Olofsson O. Hypothalamic hamartoma with gelastic seizures in Swedish children and adolescents. Eur J Paediatr Neurol 8 (2004) 35-44
6. Striano S., Striano P., Sarappa C., and Boccella P. The clinical spectrum and natural history of gelastic epilepsy-hypothalamic hamartoma syndrome. Seizure 14 (2005) 232-239
7. Berkovic S., Anderman F., Melanson D., Ethier R.E., Feindel W., and Gloor P. Hypothalamic hemartoma and ictal laughter: evolution of a characteristic epileptic syndrome and diagnostic value of magnetic resonance imaging. Ann Neurol 23 (1988) 429-439
8. Valdueza J.M., Cristante L., Dammann O., et al. Hypothalamic hamartomas: with special reference to gelastic epilepsy and surgery. Neurosurgery 34 (1994) 949-958
9. Nguyen D., Singh S., Zaatreh M., et al. Hypothalamic hamartomas: seven cases and review of the literature. Epilepsy Behav 4 (2003) 246-258
10. Boudreu E.A., Liow K., Frattali C.M., et al. Hypothalamic hamartomas and seizures: distinct natural history of isolated and Pallister-Hall cases. Epilepsia 46 (2005) 42-47
11. Wild B., Rodden F.A., Grodd W., and Ruch W. Neuronal correlates of laughter and humor. Brain 126 (2003) 2121-2138
12. Poek K. Pathological laughter and crying. In: Frederik S. (Ed). Handbook of clinical neurology Vol. 1 (1985), Elsevier, Amsterdam 219-5
13. Dabby R., Watemberg N., Lampl Y., Eilam A., Rapaport A., and Sadeh M. Pathological laughter as a symptom of midbrain infarction. Behav Neurol 15 (2004) 73-76
14. Hargrgave D.R., Mabbot D.J., and Bouffet E. Pathological laughter and behavioral change in childhood pontine glioma. J Neurooncol 77 (2006) 267-271
15. Munari C., Kahane P., Francione S., et al. Role of the hypothalamic hamartoma in the genesis of gelastic fits (a video-stereo-EEG study). Electroencephalogr Clin Neurophysiol 95 (1995) 154-160
16. Kuzniecky R., Guthrie B., Mountz J., et al. Intrinsic epileptogenesis of hypothalamic hamartomas in gelastic epilepsy. Ann Neurol 42 (1997) 60-67
17. Kerrigan J.F., Ng Y.T., Chung S., and Rekate H.L. The hypothalamic hamartoma: a model of subcortical epileptogenesis and encephalopathy. Semin Pediatr Neurol 12 (2005) 119-131
18. Arroyo Y., Santamaria J., Sanmarti F., et al. Ictal laughter associated with paroxysmal hypothalamopituitary dysfunction. Epilepsia 38 (1997) 114-117
19. DiFazio M.P., and Davis R.G. Utility of early single photon emission computed tomography (SPECT) in neonatal gelastic epilepsy associated with HH. J Child Neurol 15 (2000) 414-417
20. Fohlen M., Lellouch A., and Delalande O. Hypothalamic hamartoma with refractory epilepsy: surgical procedures and results in 18 patients. Epileptic Disord 5 (2003) 267-273
21. Palmini A., van Paesschen W., Dupont P., Van Laere K., and Van Driel G. Status gelasticus after temporal lobe lobectomy: ictal FDG-PET findings and the question of dual pathology involving hypothalamic hamartomas. Epilepsia 46 (2005) 1313-1316
22. Dericioglu N., Cataltepe O., Tezel G.G., and Saygi S. Gelastic seizures due to right temporal cortical dysplasia. Epileptic Disord 7 (2005) 137-141
23. Palmini A., Chandler C., Andermann F., et al. Resection of the lesion in patients with hypothalamic hamartomas and catastrophic epilepsy. Neurology (2002) 1338-1347 14;58
24. Rosenfeld J.V., Harvey A.S., Wrennall J., Zacharin M., and Berkovic S.F. Transcallosal resection of hypothalamic hamartomas, with control of seizures, in children with gelastic epilepsy. Neurosurgery 48 (2001) 108-118
25. Harvey A.S., Freeman J.L., and Rosenfeld J.V. Postoperative course and seizure outcome after transcallosal resection of hypothalamic hamartomas in seventeen patients with intractable gelastic epilepsy. Epilepsia 42 (2001) 216
26. 125I-iomazenil-benzodiazepine receptor binding and serum corticosterone level in a rat model. Nucl Med Biol 32 (2005) 95-100