Mental disorders and metabolic syndrome: A fatamorgana or warning reality?

Psychiatria Danubina

Volumn 19, Issue 1-2, 2007, Pages 76-86

  Jakovljević, Miro ^a   Crnčević, Željka ^b   Ljubičić, Duliano ^b   Babić, Dragan ^c   Topić, Radmila ^a   Šarić, Marija ^d  

^a KBC Zagreb   (Croatia)

^b KBC RIJEKA   (Croatia)

^c UNIVERSITY OF MOSTAR   (Bosnia and Herzegovina)

^d Croatia   (Croatia)

Author keywords

Bipolar disorder; Major depression; Metabolic syndrome; Mind body medicine; Post traumatic stress syndrome; Schizoaffective disorder; Schizophrenia

Indexed keywords

AMFEBUTAMONE; ANDROGEN; ANTIDEPRESSANT AGENT; C REACTIVE PROTEIN; CARBAMAZEPINE; CHLORPROMAZINE; CLOZAPINE; CYTOKINE; FLUOXETINE; GLUCOCORTICOID RECEPTOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LIPOPROTEIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MOOD STABILIZER; NEUROLEPTIC AGENT; OLANZAPINE; PLASMINOGEN ACTIVATOR INHIBITOR 1; QUETIAPINE; RISPERIDONE; SEROTONIN RECEPTOR; SEX HORMONE; SULPIRIDE; THIORIDAZINE; TOPIRAMATE; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VALPROIC ACID; ZONISAMIDE;

ARTICLE; AUTONOMIC NEUROPATHY; BIPOLAR DISORDER; BRAIN DISEASE; CLINICAL TRIAL; DIABETES MELLITUS; DISEASE ASSOCIATION; DYSLIPIDEMIA; GLUCOSE METABOLISM; HUMAN; HYPERGLYCEMIA; HYPERTENSION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATORY DISEASE; INSULIN RESISTANCE; LIFESTYLE; MAJOR DEPRESSION; MEDLINE; MENTAL DISEASE; METABOLIC SYNDROME X; MORBIDITY; MORTALITY; OBESITY; PATHOPHYSIOLOGY; PEER REVIEW; PERSONALITY DISORDER; POSTTRAUMATIC STRESS DISORDER; PUBLICATION; RECURRENT DISEASE; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SIDE EFFECT; STATISTICAL ANALYSIS; WEIGHT; WEIGHT GAIN; WEIGHT REDUCTION;

ALLOSTASIS; BIPOLAR DISORDER; COMBAT DISORDERS; COMORBIDITY; DEPRESSIVE DISORDER; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INSULIN RESISTANCE; MENTAL DISORDERS; METABOLIC SYNDROME X; PITUITARY-ADRENAL SYSTEM; PSYCHOTIC DISORDERS; RISK FACTORS; SCHIZOPHRENIA; STATISTICS;

EID: 34447285509     PISSN: 03535053     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Babić D, Jakovljević M, Martinac M, Šarić M, Topić R & Maslov B: Metabolic syndrome and post-traumatic stress disorder intensity: Preliminary findings. Psychiatria Danubina 2007; 19:68-75.
2. Bjorntorp P: Do stress reactions cause abdominal obesity and comorbidities? Obesity Reviews 2001; 2:73-86.
3. Blouin K, Despres JP, Couillard C, Tremblay A, Prud'homme D, Bouchard C & Tchernof A: Contribution of age and declining androgen levels to features of the metabolic syndrome in men. Metabolism - Clinical and Experimental, 2005; 54:1034-1040.
4. Bobes J: General status in bipolar disorder patients under treatment. The World Journal of Biological Psychiatry 2007(suppl 1); 8:10.
5. Bobes J: General health status in bipolar disorder patients under treatment. The World Journal of Biological Psychiatry 2007; 8:10.
6. Boston PF, Dursun SM & Reveley MA: Cholesterol and mental disorder. British Journal of Psychiatry 1996; 169:682-689.
7. Casey DE & Hansen TE: Excessive mortality and morbidity associated with schizophrenia. In Meyer JM & Nasrallah HA (eds): Medical Illness and Schizophrenia. American Psychiatric Publishing, Inc., Washington, 2003.
8. Copolov DL & Rabin RT: Endocrine disturbances in affective disorders and schizophrenia. In Nemerof CB & Loosen PT: Handbook of Clinical Psychoneuroendocrinology, 160-194, John Wiley & Sons, Chichester, 1987.
9. D'Mello DA, Narang S & Agredano G: Prevalence and consequences of metabolic syndrome in bipolar disorder. Sije anj 01, 2007 vol. 24 No 1.
10. Gans ROB: The metabolic syndrome, depression and cardiovascular disease: Interrelated conditions that share pathophysiologic mechanisms. Med Clin N Am 2006; 90:573-591.
11. Gilespie CF & Nemeroff CB: Hypercortisolemia and depression. Psychosom Med 2005; 67(suppl):s26-s28.
12. Heiskanen TH, Niskanen LG, Hintikka JJ, Koivumma-Honkanen HT, Honkalampi KM & Viinamaki HT: Metabolic syndrome and depression: a cross-sectional analysis. J Clin Psychiatry 2006; 67:1422-7.
13. Holt RIG, Pevelert RC & Byrne CD: Schizophrenia, the metabolic syndrome and diabetes. Diabetic Medicine 2004; 21:515-523.
14. Jakovljević M: Neuroendokrinološki pokazatelji u liječenju depresija. Doktorska disertacija. Medicinski fakultet Sveu_Cacili-acsta u Zagrebu, 1989.
15. Jakovljević M, Bohaček N, Plavšić V, et al: Clinical and biological effects of savoxapine, a novel neuroleptic drug. Psychiatria Danubina, 1989; 1:247-260.
16. Jakovljević M, Mueck-Šeler D, Kenfelj H, Plavšić V, Biočina S, Kastratović D & Ljubičić D: Basal cortisol, dexamethasone suppression test and platelet 5-HT in recurrent (unipolar) major depression, schizophrenia and schizoaffective disorder. Psychiatria Danubina 1991; 4:389-414.a
17. Jakovljević M, Kaštelan M, Kenfelj H, Plavšić V, Mihaljević-Peleš A, Miličević Ž, Papić D, Ljubičić D & Koršić M: Immune function and hypothalamic-pituitary-adrenal (HPA) axis activity in recurrent (unipolar) major depression and schizophrenia. Psychiatria Danuina 1991; 3:415-433.b
18. Jakovljević M: Metabolic syndrome and selective serotonin reuptake inhibitors. Psychiatria Danubina 2004; 16:258-259
19. Jakovljević M, Šarić M, Nad S, Topić R & Vuksan-Śusa B: Metabolic syndrome, somatic and psychiatric comorbidity in war veterans with post-traumatic stress disorder: preliminary findings. Psychiatria Danubina 2006; 18:169-176.
20. Jakovljević M, Babić D, Martinac M, Maslov B & Topić R: Metabolic syndrome in war veterans with post-traumatic stress disorder with and without depression comorbidity. The World Journal of Biological Psychiatry 2007 (suppl 1); 8:67.
21. Jakovljević M, Šarić M, Topić R & Marčinko D: Mental disorders and metabolic syndrome: A critical review. The World Journal of Biological Psychiatry 2007(suppl 1); 8:91.
22. Ljubičić D: Neuroendokrini aspekti shizofrenije i depresije. Magistarska radnja Medicinski fakultet Sveucčilišta u Rijeci, 1992.
23. Marčinko D, Marčinko A & Jakovljević M The first episode psychosis and the metabolic syndrome - preliminary findings (submitted).
24. Maslov B, Jakovljević M, Martinac M, Babić D & Koršić 34: Metabolic syndrome in patients with schizophrenia preliminary findings (submitted)
25. McCarron RM & Keenen CR: The metabolic syndrome. In Bermudes RA, Keck PE &McElroy SL (eds): Managing metabolic abnormalities in the psychiatrically ill, 25-52. American Psychiatric Publishing, Inc. Washington, DC, 2007.
26. McElroy SL, Guerdjikova A, Kotwal R & Keck PE: Severe mental illness and obesity. In Bermudes RA, Keck PE & McElroy SL (eds): Managing Metabolic Abnormalities in the Psychiatrically ill - A Clinical Guide for Psychiatrist, 55-119. American Psychiatric Publishing, Inc., Washington, 2007.
27. McEwen BS & WingfieM JC: The concept of allostasis in biology and biomedicine. Horm Behav 2003; 43:2-15.
28. McIntyre RS, Soczynska JK, Bordbar K & Konarski JZ. Antipsychotic-association weight gain - A synthesis and clinical recommendations. In Bermudes RA, Keck PE & McElroy SL (eds): Managing Metabolic Abnormalities in the Psychiatrically Ill, 165-201. American Psychiatric Publishing, Inc., Washington, 2007.
29. Meyer JM: Serum lipids - Effects of antipsychotics. In Bermudes RA, Keck PE & McElroy SL (eds): Managing Metabolic abnormalities in the Psychiatrically Ill, 239-276. American Psychiatric Publishing, Inc., Washington, 2007.
30. Moller DE & Kaufman KD: Metabolic syndrome: A clinical and molecular perspective. Annu. Rev. Med. 2005; 56:45-62.
31. Mueck-Šeler D, Pivac N, Jakovljević M, Šagud M & Mihaljević A: Platelet 5-HT concentration and comorbid depression in war veterans with and without posttraumatic stress disorder. Journal of Affective Disorders 2003; 75:171-179.
32. Muldoon MF, Mackey RH, Korytkowski MT, Flory JD, Pollock BG & Manuck SB: The metabolic syndrome is associated with reduced central serotonergic responsivity in healthy community volunteers. The Journal of Clinical Endocrinology & Metabolism 2006; 91:718-721.
33. Nelson JC & Davis JM: DST studies in psychotic depression: A meta-analysis. Am J Psychiatry, 1997; 154:1497-1503.
34. Newcomer JW: Glucose metabolism - Effects of atypical antipsychotics. In Bermudes RA, Keck PE & McElroy SL (eds): Managing Metabolic Abnormalities in the Psychiatrically Ill, 165-201. American Psychiatric Publishing, Inc., Washington, 2007.
35. Pomeroy C, Mitchell JE, Roering J & Crow S: Medical Complications of Psychiatric Illness. American Psychiatric Publishing, Inc., Washington, 2002.
36. Rao R: Metabolic syndrome in schizophrenia: A study from India. The World Journal of Biological Psychiatry 2007 (suppl 1); 8:140.
37. Ryan MCM & Thakore JH: Physical consequences of schizophrenia and its treatment - The metabolic syndrome. Life Sciences 2002; 71:239-257.
38. Singh RB, Pella D, Mechirova V & Otsuka K: Can brain dysfunction be a predisposing factor for metabolic syndrome. Biomedicine & Pharmacotherapy 2004; 58: s56-s68.
39. Sterling P & Eyer J: Allostasis: a new paradigm to explain arousal pathology. In Fisher S Reason J (eds): Handbook of Life Stress, Cognition and Health, 629-649. Wiley, New York, 1988.
40. Thakore JH: Metabolic syndrome and schizophrenia. Br J Psychiatry 2005; 186:455-456.
41. Toalson P, Ahmed S, Hardy T & Kabinoff G: The metabolic syndrome in patients with severe mental illness. Prim Care Companion J Clin Psychiatry 2004; 6:152-158.
42. Violanti JM, Fekedulegn D, Hartley TA, Andrew ME, Charles LE, Mnatsakanova A & Burchfiel CM: Police trauma and cardiovascular disease: Association between PTSD symptoms and metabolic syndrome. IJEMH 2006; 8:227-237.
43. Vogelzangs N, Suthers K, Ferrucci L, Simonsick EM, Ble A, Schrager M, Bandinelli S, Lauretani F, Gianelli SV & Penninx BW: Hypercortisolemic depression is associated with the metabolic syndrome in late-life. Psychoneuroendocrinology 2007; doi:10.1016/ j.psyneuen.2006.11.009
44. Vuksan-Ćusa B, Jakovljević M, Topić R, Šarić M & Nad S: Metabolic syndrome in patients with bipolar disorders: Preliminary findings. (submitted)
45. Yamamoto K & Hornykiewitcz O: Proposal for a nradrenaline hypothesis of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2004; 28:913-22.