Synthesis and structure-antituberculosis activity relationship of 1H-indole-2,3-dione derivatives

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 17, 2007, Pages 5888-5904

  Karali, Nilgün ^a   Gürsoy, Aysel ^a   Kandemirli, Fatma ^b   Shvets, Nathaly ^c   Kaynak, F Betül ^d   Özbey, Süheyla ^d   Kovalishyn, Vasyl ^e   Dimoglo, Anatholy ^c,f  

^a ISTANBUL UNIVERSITY   (Turkey)

^b KOCAELI UNIVERSITY   (Turkey)

^c GEBZE TECHNICAL UNIVERSITY   (Turkey)

^d HACETTEPE UNIVERSITY   (Turkey)

^e INSTITUTE OF BIOORGANIC CHEMISTRY AND PETROCHEMISTRY   (Ukraine)

^f INSTITUTE OF APPLIED PHYSICS   (Moldova)

Author keywords

1H Indole 2,3 diones; Antituberculosis activity; Electronic topological method (ETM); Structure activity relationships

Indexed keywords

1 MORPHOLINO 5 NITRO 1H INDOLE 2,3 DIONE 3 THIOSEMICARBAZONE DERIVATIVE; 1 PIPERIDINOMETHYL 5 NITRO 1H INDOLE 2,3 DIONE 3 THIOSEMICARBAZONE DERIVATIVE; 1H INDOLE 2,3 DIONE DERIVATIVE; 5 FLUORO 1 MORPHOLINO 1H INDOLE 2,3 DIONE 3 THIOSEMICARBAZONE DERIVATIVE; 5 FLUORO 1 PIPERIDINOMETHYL 1H INDOLE 2,3 DIONE 3 THIOSEMICARBAZONE DERIVATIVE; 5 FLUORO 1H INDOLE 2,3 DIONE 3 THIOSEMICARBAZONE DERIVATIVE; 5 NITRO 1H INDOLE 2,3 DIONE 3 [(4 OXO 1,3 THIAZOLIDIN 2 YLIDENE)HYDRAZONE DERIVATIVE; 5 NITRO 1H INDOLE 2,3 DIONE 3 THIOSEMICARBAZONE DERIVATIVE; INDOLE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ALGORITHM; ANIMAL CELL; ARTICLE; ARTIFICIAL NEURAL NETWORK; BACTERIAL STRAIN; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; TECHNIQUE; X RAY DIFFRACTION;

ANTITUBERCULAR AGENTS; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; HYDROGEN BONDING; INDOLES; INHIBITORY CONCENTRATION 50; MICROBIAL VIABILITY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

MYCOBACTERIUM TUBERCULOSIS;

EID: 34447274051     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.05.063     Document Type: Article

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