Clinical study on effect of Astragalus Injection and its immuno-regulation action in treating chronic aplastic anemia

Chinese Journal of Integrative Medicine

Volumn 13, Issue 2, 2007, Pages 98-102

  Wang, Mao Sheng ^a   Li, Jun ^a   Di, Hai Xia ^a   Li, Zhen Li ^a   Yang, Shu Lian ^a   Hou, Wei ^a   Yan, Jin Yu ^a   Zhao, Xiao Min ^a  

^a TCM Hospital of Langfang City   (China)

Author keywords

Astragalus Injection; Chronic aplastic anemia; Interleukin 2; T lymphocyte subsets; Tumor necrosis factor

Indexed keywords

ASTRAGALUS EXTRACT; INTERLEUKIN 2; STANOZOLOL; THIOL; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ALLERGIC REACTION; APLASTIC ANEMIA; ARTICLE; BONE MARROW; CHRONIC DISEASE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; FOLLOW UP; HEMOGLOBIN BLOOD LEVEL; HUMAN; IMMUNOREGULATION; LEUKOCYTE; LIVER DYSFUNCTION; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETICULUM CELL; SIDE EFFECT; T LYMPHOCYTE; THROMBOCYTE; UNSPECIFIED SIDE EFFECT;

ANEMIA, APLASTIC; ASTRAGALUS PLANT; BONE MARROW; CHRONIC DISEASE; DRUGS, CHINESE HERBAL; FOLLOW-UP STUDIES; HUMANS; INJECTIONS; INTERLEUKIN-2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34447272425     PISSN: 16720415     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11655-007-0098-5     Document Type: Article

References (11)

1. Zhang ZN, editor. Standard for diagnosis and treatment of blood disease. 2nd ed. Beijing: Science Press, 1998: 33-36.
2. Maciejewski JP, Hlbbs JR, Anderson S, et al. Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure. Exp Hematol 1994;22:1102-1110.
3. Mentzel U, Vogt H, Rossol R, et al. Analysis of lymphocyte subsets in patients with aplastic anemia before and during immunosuppressive therapy. Ann Hematol 1993;66:127-129.
4. He H, Shao ZH, He GS, et al. Role of Th1 cell in the pathogenesis of aplastic anemia. Chin J Hematol 2002;23(11) :547-577.
5. Shao ZH, Chen KQ, Chen GB, et al. Correlation between the serum levels of interleukin-2 and soluble interleukin-2 receptor and the response to immunosuppressive therapy in severe aplastic anemia patients. Chin J Hematol 1997;18(4) :180-182.
6. Zhang T, Sun BZ, Feng Q, et al. A comparative study on the expressions of IL-4, IFN-gamma and TNF-alpha in BMMNC of acute and chronic aplastic anemia patients. Chin J Hematol 2000;21 (10):530-532.
7. Selleri C, Sato T, Anderson S, et al. Interferon-gamma and tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and induce programmed cell death. J Cell Physiol 1995;165:538-546.
8. Xu SF, OU YX. Progress on study of immunological pathogenetic mechanism of aplastic anemia. Med J Natl Defend Forces Northwest China 2002;23(1):56-58.
9. Wang ZG, Zhou JH, editors. Progress on pharmacological and clinical study of Chinese materia medica (Vol. 1). Beijing: Chinese Publishing House of Science and Technology, 1992:254-261.
10. Liu XK, Yu ZK. Progress on study of constituents and pharmacologic activity of astragalus. Shanghai Med Pharm J 1995;16(2):23-28.
11. Hu JM. Effect of astragalus polysaccharides on progenitors of granular macrophage series in mice. Chin J Exp Clin Immunol 1997;9(6):53-55.