Altered expression of prohibitin in psoriatic lesions and its cellular implication

Biochemical and Biophysical Research Communications

Volumn 360, Issue 3, 2007, Pages 653-658

  Kim, Soon Young ^a   Kim, Younghwa ^a   Hwang, Ha Young ^a   Kim, Tae Yoon ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Anthralin; Prohibitin; Proliferation; Psoriasis

Indexed keywords

DITHRANOL; GENE PRODUCT; PROHIBITIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL ACTIVITY; CELL CULTURE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL DEATH; CONTROLLED STUDY; DRUG MECHANISM; DRUG SENSITIVITY; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PATHOGENESIS; PRIORITY JOURNAL; PSORIASIS;

ANTHRALIN; DERMATOLOGIC AGENTS; GENE EXPRESSION REGULATION; HUMANS; KERATINOCYTES; PSORIASIS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; S PHASE;

EID: 34447265545     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.06.118     Document Type: Article

References (25)

1. Nickoloff B.J. The immunologic and genetic basis of psoriasis. Arch. Dermatol. 135 (1999) 1104-1110
2. Mishra S., Murphy L.C., Nyomba B.L., and Murphy L.J. Prohibitin: a potential target for new therapeutics. Trends Mol. Med. 11 (2005) 192-197
3. McClung J.K., Danner D.B., Stewart D.A., Smith J.R., Schneider E.L., Lumpkin C.K., Dell'Orco R.T., and Nuell M.J. Isolation of a cDNA that hybrid selects antiproliferative mRNA from rat liver. Biochem. Biophys. Res. Commun. 164 (1989) 1316-1322
4. Nuell M.J., Stewart D.A., Walker L., Friedman V., Wood C.M., Owens G.A., Smith J.R., Schneider E.L., Dell' Orco R., Lumpkin C.K., et al. Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells. Mol. Cell. Biol. 11 (1991) 1372-1381
5. Wang S., Nath N., Adlam M., and Chellappan S. Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function. Oncogene 18 (1999) 3501-3510
6. Wang S., Nath N., Fusaro G., and Chellappan S. Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals. Mol. Cell. Biol. 19 (1999) 7447-7460
7. Wang S., Zhang B., and Faller D.V. Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth. EMBO J. 21 (2002) 3019-3028
8. Wang S., Fusaro G., Padmanabhan J., and Chellappan S.P. Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression. Oncogene 21 (2002) 8388-8396
9. Thompson W.E., Asselin E., Branch A., Stiles J.K., Sutovsky P., Lai L., Im G.S., Prather R.S., Isom S.C., Rucker III E., and Tsang B.K. Regulation of prohibitin expression during follicular development and atresia in the mammalian ovary. Biol. Reprod. 71 (2004) 282-290
10. Fusaro G., Wang S., and Chellappan S. Differential regulation of Rb family proteins and prohibitin during camptothecin-induced apoptosis. Oncogene 21 (2002) 4539-4548
11. Sui G., Soohoo C., Affar el B., Gay F., Shi Y., Forrester W.C., and Shi Y. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99 (2002) 5515-5520
12. Wilson R., and Spier R.E. Biochemistry of hybridoma technology. Dev. Biol. Stand. 66 (1987) 161-167
13. Kim H.J., Kim H.J., Lim S.C., Kim S.H., and Kim T.Y. Induction of apoptosis and expression of cell cycle regulatory proteins in response to a phytosphingosine derivative in HaCaT human keratinocyte cells. Mol. Cell 16 (2003) 331-337
14. Fulda S., Scaffidi C., Susin S.A., Krammer P.H., Kroemer G., Peter M.E., and Debatin K.M. Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid. J. Biol. Chem. 273 (1998) 33942-33948
15. Swinkels O.Q., Prins M., Gerritsen M.J., van Vlijmen-Willems I.M., van der Valk P.G., and van de Kerkhof P.C. An immunohistochemical assessment of the response of the psoriatic lesion to single and repeated applications of high-dose dithranol cream. Skin Pharmacol. Appl. Skin Physiol. 15 (2002) 393-400
16. McGill A., Frank A., Emmett N., Turnbull D.M., Birch-Machin M.A., and Reynolds N.J. The anti-psoriatic drug anthralin accumulates in keratinocyte mitochondria, dissipates mitochondrial membrane potential, and induces apoptosis through a pathway dependent on respiratory competent mitochondria. FASEB J. 19 (2005) 1012-1014
17. Woo Y., Krueger W., Kaur A., and Churchill G. Experimental design for three-color and four-color gene expression microarrays. Bioinformatics 21 Suppl. 1 (2005) i459-i467
18. Manjeshwar S., Branam D.E., Lerner M.R., Brackett D.J., and Jupe E.R. Tumor suppression by the prohibitin gene 3′ untranslated region RNA in human breast cancer. Cancer Res. 63 (2003) 5251-5256
19. Takahashi H., Manabe A., Ishida-Yamamoto A., Hashimoto Y., and Iizuka H. Aberrant expression of apoptosis-related molecules in psoriatic epidermis. J. Dermatol. Sci. 28 (2002) 187-197
20. Kocak M., Bozdogan O., Erkek E., Atasoy P., and Birol A. Examination of Bcl-2, Bcl-X and bax protein expression in psoriasis. Int. J. Dermatol. 42 (2003) 789-793
21. Mildner M., Weninger W., Trautinger F., Ban J., and Tschachler E. UVA and UVB radiation differentially regulate vascular endothelial growth factor expression in keratinocyte-derived cell lines and in human keratinocytes. Photochem. Photobiol. 70 (1999) 674-679
22. Bonnekoh B., Wevers A., Geisel J., Rasokat H., and Mahrle G. Antiproliferative potential of zidovudine in human keratinocyte cultures. J. Am. Acad. Dermatol. 25 (1991) 483-490
23. Nijtmans L.G., de Jong L., Artal Sanz M., Coates P.J., Berden J.A., Back J.W., Muijsers A.O., van der Spek H., and Grivell L.A. Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins. EMBO J. 19 (2000) 2444-2451
24. Artal-Sanz M., Tsang W.Y., Willems E.M., Grivell L.A., Lemire B.D., van der Spek H., and Nijtmans L.G. The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans. J. Biol. Chem. 278 (2003) 32091-32099
25. Steglich G., Neupert W., and Langer T. Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria. Mol. Cell. Biol. 19 (1999) 3435-3442