A novel single nucleotide polymorphism, IVS2 -97A>T, in the prostaglandin F2α receptor gene was identified among the Malaysian patients with glaucoma

Kobe Journal of Medical Sciences

Volumn 53, Issue 2, 2007, Pages 49-52

  Hoh, Boon Peng ^a   Zahary, Mohd Nizam ^a   Tajudin, Liza Sharmini Ahmad ^a   Chieng, Li Lin ^a   Cheong, Min Teck ^a   Sidek, Mohamad Ros ^a   Zulkifli, Azman ^a   Zilfalil, Bin Alwi ^a  

^a SCHOOL OF HEALTH SCIENCES   (Malaysia)

Author keywords

Denaturing high performance liquid chromatography (dHPLC); Glaucoma; Polymorphism; The prostaglandin F2 receptor gene

Indexed keywords

PROSTAGLANDIN F2 ALPHA RECEPTOR; PROSTAGLANDIN RECEPTOR; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DNA SEQUENCE; GENE FREQUENCY; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; GLAUCOMA; HETEROZYGOTE; HOMOZYGOTE; HUMAN; INTRAOCULAR PRESSURE; MAJOR CLINICAL STUDY; MALAYSIA; NUCLEOTIDE SEQUENCE; RECEPTOR GENE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

GENE FREQUENCY; GLAUCOMA; HUMANS; MALAYSIA; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, PROSTAGLANDIN; SEQUENCE ANALYSIS, DNA;

EID: 34447248748     PISSN: 00232513     EISSN: 18830498     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Bito L.Z. 1997. Prostaglandin: A new approach to glaucoma management with a new, intriguing side effect. Survey of Ophthalmology 41: S1-14.
2. den Dunnen, J.T. and Antonarakis, S.E. 2000. Mutation nomenclature extensions and suggestions to describe complex mutations: a discussion. Human Mutation 15: 7-12.
3. Cauffiez, C., Klinzig, F., Rat, E., Tournel, G., Allorge, D., Chevalier, D., et al. 2004. Functional characterization of genetic polymorphisms identified in the human cytochrome P450 4F12 (CYP4F12) promoter region. Biochemistry and Pharmacology 67: 2231-2238.
4. Gandofti, S.A. and Cimino, L. 2003. Effect of bimatoprost on patients with primary open-angle glaucoma or ocular hypertension who are nonresponders to latanoprost. Ophtalmology 110: 609-614.
5. 2a (PGF2a) Receptor. Journal Biological Chemistry 43: 27147-27153.
6. Lai, L.P., Su, Y.N., Chiang, F.T., Juang J.M., Liu, Y.B. et al. 2005. Denaturing high-performance liquid chromatography screening of the long QT syndrome-related cardiac sodium and potassium channel genes and identificatioin of novel mutations and single nucleotide polymorphisms. Journal of Human Genetics 50: 490-496.
7. Marian, A. J., Safavi, F., Ferlic, L., Dunn, J. K., Gotto, A. M. and Ballantyne, C. M. 2000. Interactions between angiotensin-I converting enzyme insertion/deletion polymorphism and response of plasma lipids and coronary atherosclerosis to treatment with fluvastatin: the lipoprotein and coronary atherosclerosis study. Journal of the American College of Cardiology 35: 89-95.
8. Netland, P.A., Laundry, T., Sullivan, E.K., Andrew, R. et al. 2001. Travoprost compared with Latanoprost and Timolol in patients with open-angle glaucoma or ocular hypertension. American Journal of Ophthalmology 132: 472-484.
9. Oscarson, M., McLellan, R. A., Asp, V., Ledesma, M., Ruiz, M. L., Sinues, B., et al. 2002. Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity. Human Mutation 20: 275-283.
10. Rozen, S. and Skaletsky, H. J. 1997. Primer 3. Code available at http://www-genome.wi.mit.edu/genome_software/other/primer3.html.
11. Shimoda, K., Someya, T., Morita, S., Hirokane, G., Yokono, A., Takahashi, S., et al. 2002. Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position-2964 in the 5V-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizophrenia. Progress in Neuro-psychopharmacology and Biological Psychiatry 26: 261-265.
12. Sivakumaran, T. A., Kucheria, K. and Oefner, P. J. 2003. Denaturing high performance liquid chromatography in the molecular diagnosis of genetic disorders. Current Science 84: 291-296.
13. Xiao, W. and Oefner, P.J. 2001. Denaturing high performance liquid chromatography: A review. Human Mutation 17: 439-474.