Endothelin-B receptors on suprachoroidal melanocytes mediate an endothelin-1-induced increase in the intracellular calcium concentration of rabbit ocular suprachoroidal tissue

Current Eye Research

Volumn 32, Issue 6, 2007, Pages 585-591

  Hirose, Akira ^a,b   Azuma, Hiroshi ^c   Tokoro, Takashi ^a   Hirai, Keiji ^c  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Endothelin 1; Endothelin B receptor; Fura 2 microfluorophotometry; Immuno electron microscopy; Suprachoroidal melanocytes

Indexed keywords

CALCIUM; ENDOTHELIN 1; ENDOTHELIN 3; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR AGONIST; FURA 2; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N ACETYLENDOTHELIN 1 [6-21][11,15 ALANINE];

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CHOROID; CONTROLLED STUDY; FLUOROPHOTOMETRY; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MELANOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RETINA; SKIN CELL; TISSUE DISTRIBUTION; UPREGULATION; VITREOUS BODY;

ANIMALS; CALCIUM; CHOROID; CYTOPHOTOMETRY; ENDOTHELIN-1; ENDOTHELIN-3; ENDOTHELINS; FLUORESCENT DYES; FURA-2; IMMUNOENZYME TECHNIQUES; MALE; MELANOCYTES; MICROSCOPY, IMMUNOELECTRON; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PIPERIDINES; RABBITS; RECEPTOR, ENDOTHELIN B;

EID: 34447136150     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.1080/02713680701391529     Document Type: Article

References (20)

1. Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
2. Rubanyi GM, Polokoff MA. Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev. 1994;46:325-415.
3. Opgenorth TJ. Endothelin receptor antagonism. Adv Pharmacol. 1995;33:1-65.
4. Pang IH, Yorio T. Ocular actions of endothelins. Proc Soc Exp Biol Med. 1997;215:21-34.
5. Takagi H, Reinach PS, Tachado SD, Yoshimura N. Endothelin-mediated cell signaling and proliferation in cultured rabbit corneal epithelial cells. Invest Ophthalmol Vis Sci. 1994;35:134-142.
6. 2+ signaling and isoform expression in bovine corneal epithelial cells. Invest Ophthalmol Vis Sci. 1997;38:130-141.
7. Hogan MJ, Alvarado JA, Weddell JE. Histology of the Human Eye. Philadelphia: Saunders; 1971:
8. 2+ signaling in human melanocytes. Pflügers Arch. 1998;435:350-356.
9. Yada Y, Higuchi K, Imokawa G. Effects of endothelins on signal transduction and proliferation in human melanocytes. J Biol Chem. 1991;266:18352-18357.
10. Hu DN. Regulation of growth and melanogenesis of uveal melanocytes. Pigment Cell Res. 2000;13:S81-S86.
11. Boissy RE. The melanocyte. Its structure, function, and subpopulations in skin, eyes, and hair. Dermatol Clin. 1988;6:161-173.
12. Torczynski E. Choroid and suprachoroid. In: Jakobiec FA, ed. Ocular Anatomy, Embryology, and Teratology. Philadelphia: Harper & Row; 1982:553-585.
13. 2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths. Cell Calcium. 1985;6:145-157.
14. Toda A, Suzuki I, Im S, et al. Endothelin-1 is a paracrine growth factor that modulates melanogenesis of human melanocytes and participates in their responses to ultraviolet radiation. Cell Growth Differ. 1998;9:575-584.
15. Imokawa G. Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders. Pigment Cell Res. 2004;17:96-110.
16. Lepple-Wienhues A, Becker M, Stahl F, et al. Endothelin-like immunoreactivity in the aqueous humour and in conditioned medium from cultured ciliary epithelial cells. Curr Eye Res. 1992;11:1041-1046.
17. Tezel G, Kass MA, Kolker AE, Becker B, Wax MB. Plasma and aqueous humor endothelin levels in primary open-angle glaucoma. J Glaucoma. 1997;6:83-89.
18. Hollo G, Lakatos P, Vargha P. Immediate increase in aqueous humour endothelin 1 concentration and intra-ocular pressure after argon laser trabeculoplasty in the rabbit. Ophthalmologica. 2000;214:292-295.
19. Cole DF, Monro PA. The use of fluorescein-labelled dextrans in investigation of aqueous humour outflow in the rabbit. Exp Eye Res. 1976;23:571-585.
20. Bill A, Phillips CI. Uveoscleral drainage of aqueous humour in human eyes. Exp Eye Res. 1971;12:275-281.