T-cell sensitivity: A microRNA regulates the sensitivity of the T-cell receptor

Immunology and Cell Biology

Volumn 85, Issue 5, 2007, Pages 346-347

  Laufer, Terri M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; T LYMPHOCYTE RECEPTOR;

ANTIGEN PRESENTING CELL; B LYMPHOCYTE; CANCER IMMUNOTHERAPY; CELL MATURATION; CELL SURVIVAL; GENE EXPRESSION; HUMAN; IMMUNE RESPONSE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; MOLECULAR MECHANICS; NOTE; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; T LYMPHOCYTE;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; PHOSPHOPROTEIN PHOSPHATASE; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 34447128812     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/sj.icb.7100073     Document Type: Note

References (4)

1. Goldrath AW, Bevan MJ. Selecting and maintaining a diverse T-cell repertoire. Nature 1999; 402: 255-262.
2. Li QJ, Chau J, Ebert PJ, Sylvester G, Min H, Liu G et al. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 2007; 129: 147-161.
3. Chen CZ, Li L, Lodish HF, Bartel DP. MicroRNAs modulate hematopoietic lineage differentiation. Science 2004; 303: 83-86.
4. Neilson JR, Zheng GX, Burge CB, Sharp PA. Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev 2007; 21: 578-589.