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Volumn 17, Issue 15, 2007, Pages 4102-4106

Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus

Author keywords

Amphiphilic cationic; Antibacterial activity; MRSA; Quinine derived

Indexed keywords

AMPHOPHILE; QUININE DERIVATIVE;

EID: 34447126353     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.065     Document Type: Article
Times cited : (13)

References (21)
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    • Merianos J.J. Quaternary Ammonium Antimicrobial Compounds. In: Block S.S. (Ed). Disinfection, Sterilization, and Preservation. 4th ed. (1991), Lea and Febiger, Philadelphia 225-255
    • (1991) Disinfection, Sterilization, and Preservation. 4th ed. , pp. 225-255
    • Merianos, J.J.1
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    • Centers for Disease Control and Prevention. Staphylococcus aureus resistant to vancomycin-United States, MMWR. Moribid. Morial. Wkly. Rep. 2002, 51, 565.
  • 9
    • 34447131686 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. Public heath dispatch: vancomycin-resistant Staphylococcus aureus-Pennsylvania, MMWR. Moribid. Morial. Wkly. Rep. 2002, 51, 902.
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    • Centers for Disease Control and Prevention. Four pediatric deaths. from community-acquired methicillin-resistant Staphylococcus aureus-Minnesota and North Dakota, 1997-1999. MMWR. Morbid. Mortal. Wkly. Rep. 1999, 48, 707.
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    • note
    • 6): 193.2, 159.0, 148.4, 148.2, 144.1, 140.9, 138.8, 132.3, 130.9, 128.5, 126.3, 124.2, 123.0, 119.9, 116.8, 101.5, 65.8, 62.8, 61.0, 57.9, 57.2, 56.8, 53.8,...
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    • National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Fifth Edition; Approved standard M7-A5. Wayne, PA: NCCLS; 2001.
  • 19
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    • note
    • 5cell/mL. The same inoculum was added to drug-free medium as a growth control. The test tubes were incubated in a water bath at 30 °C. Next, 100 μL of samples was taken from each tube at known time intervals, centrifuged, and washed three times with fresh Mueller-Hinton broth. After vortexed vigorously for 10 s, the suspension was suitably diluted and spread onto Mueller-Hinton agar plates. The plates were incubated at 30 °C for 24 h and colonies were counted. Each number of viable cells was determined from three-independent experiments performed in triplicate.
  • 20
    • 34447127054 scopus 로고    scopus 로고
    • National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Disk Susceptibility Tests. Eighth Edition; Approved Standard M2-A8. Wayne, PA: NCCLS; 2003.
  • 21
    • 34447136314 scopus 로고    scopus 로고
    • note
    • 9 cells/mL) was mixed with 0.1 mL of test substances at a series of concentrations (1-2000 μg/mL). The mixtures were incubated at 37 °C for 1 h. After incubation, tubes were centrifuged at 2000g for 10 min. The supernants were transferred into 96-well polystyrene plates (Costar 3590, incorporated) and the optical density was measured at 540 nm using MTP120 microplate reader (Colona Electric, Japan). The values for 0% and 100% lysis were determined by incubating erythrocytes with PBS, and 0.1% (v/v) Triton X-100 (Amresco 0694), respectively. Assays were carried out in triplicate and the results were confirmed in three-independent experiments.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.