Genetic intratumour heterogeneity in high-grade brain tumours is associated with telomere-dependent mitotic instability

Neuropathology and Applied Neurobiology

Volumn 33, Issue 4, 2007, Pages 440-454

  Glanz, C ^a,b   Rebetz, J ^a,b,c   Stewenius Y ^a   Persson, A ^a   Englund, E ^a   Mandahl, N ^a   Mertens, F ^a   Salford, L G ^a   Widegren, B ^a,b,c   Fan, X ^a,b,c   Gisselsson, D ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Anaphase bridge; Clonal evolution; Genomic instability; Glioblastoma multiforme; Telomere; Xenograft

Indexed keywords

ADOLESCENT; ADULT; AGED; ANAPHASE; ARTICLE; ASTROCYTOMA; BRAIN BIOPSY; BRAIN TUMOR; CELL DIVISION; CHILD; CHROMATID; CHROMOSOME; CHROMOSOME ANALYSIS; CHROMOSOME SEGREGATION; CLINICAL ARTICLE; CLONE; CONTROLLED STUDY; EPENDYMOMA; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENOMIC INSTABILITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; KARYOTYPE; MALE; MEDULLOBLASTOMA; MITOSIS; OLIGODENDROGLIOMA; PILOCYTIC ASTROCYTOMA; PRIORITY JOURNAL; SISTER CHROMATID; TELOMERE; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; XENOGRAFT;

ADULT; AGED; ANIMALS; BRAIN NEOPLASMS; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CHROMATIDS; CHROMOSOME SEGREGATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MICE; MICE, INBRED NOD; MICE, SCID; MIDDLE AGED; MITOTIC SPINDLE APPARATUS; NEOPLASM TRANSPLANTATION; PHENOTYPE; SISTER CHROMATID EXCHANGE; TELOMERASE; TELOMERE; TRANSPLANTATION, HETEROLOGOUS;

EID: 34447125088     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/j.1365-2990.2007.00832.x     Document Type: Article

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