The S100 proteins for screening and prognostic grading of bladder cancer

Histology and Histopathology

Volumn 22, Issue 7-9, 2007, Pages 1025-1032

  Yao, R ^a   Davidson, D D ^b   Lopez Beltran, A ^c   MacLennan, G T ^d   Montironi, R ^e   Cheng, L ^b  

^a USA   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CÓRDOBA   (Spain)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

^e UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

Biomarkers; Bladder; Neoplasia; Proteomics; S100 proteins; Transitional cell carcinoma; Urinary tract; Urothelial carcinoma

Indexed keywords

CALCIUM BINDING PROTEIN; CALVASCULIN; HETERODIMER; HOMODIMER; PROTEIN S 100; PROTEIN S 100A11; PROTEIN S 100A8; PROTEIN S 100A9; PROTEIN S 100C; PSORIASIN; UNCLASSIFIED DRUG;

APOPTOSIS; BLADDER CANCER; CALCIUM HOMEOSTASIS; CANCER GRADING; CANCER GROWTH; CANCER INVASION; CANCER SCREENING; CANCER SURVIVAL; CARCINOGENESIS; CARDIOMYOPATHY; CELL DIFFERENTIATION; CELL GROWTH; CELL SURVIVAL; CYTOSKELETON; DEGENERATIVE DISEASE; ENZYME ACTIVITY; EXTRACELLULAR SPACE; GENE OVEREXPRESSION; HUMAN; IMMUNE DEFICIENCY; IMMUNE RESPONSE; INFLAMMATION; INTRACELLULAR SPACE; MALIGNANT NEOPLASTIC DISEASE; METASTASIS; NONHUMAN; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MOTIF; REVIEW; BLADDER TUMOR; CLASSIFICATION; FORECASTING; GENETIC SCREENING; GENETICS; METABOLISM; PATHOLOGY;

ANIMALIA;

FORECASTING; GENETIC SCREENING; HUMANS; PROGNOSIS; S100 PROTEINS; URINARY BLADDER NEOPLASMS;

EID: 34447115041     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (65)

1. Agerbaek M., Alsner J., Marcussen N., Lundbeck F. and Von Der Masse H. (2006). Focal S10OA4 Protein Expression Is an Independent Predictor of Development of Metastatic Disease in Cystectomized Bladder Cancer Patients. Eur. Urol. 50, 777-785.
2. Ambartsumian N., Klingelhofer J., Grigorian M., Christensen C., Kriajevska M., Tulchinsky E., Georgiev G., Berezin V., Bock E., Rygaard J., Cao R., Cao Y. and Lukanidin E. (2001). The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor. Oncogene 20, 4685-4695.
3. Bollito E.R., Pacchioni D., Lopez-Beltran A., Volante M., Terrone C., Casetta G., Mari M., DePompa R., Cappia S. and Papotti M. (2005). Immunohistochemical study of neuroendocrine differentiation in primary glandular lesions and tumors of the urinary bladder. Anal. Quant. Cytol. Histol. 27, 218-224.
4. Brandau S. and Bohle A. (2001). Bladder cancer. I. Molecular and genetic basis of carcinogenesis. Eur. Urol. 39, 491-497.
5. 2+)-binding S100 proteins. Histol. Histopathol. 16, 707-712.
6. Broome A.M., Ryan D. and Eckert R.L. (2003). S100 protein subcellular localization during epidermal differentiation and psoriasis. J. Histochem. Cytochem. 51, 675-685.
7. Brouard M.C., Saurat J.H., Ghanem G. and Siegenthaler G. (2002). Urinary excretion of epidermal-type fatty acid-binding protein and S100A7 protein in patients with cutaneous melanoma. Melanoma Res. 12, 627-631.
8. Celis J.E., Rasmussen H.H., Vorum H., Madsen P., Honors B., Wolf H. and Orntoft T.F. (1996). Bladder squamous cell carcinomas express psoriasin and externalize it to the urine. J. Urol. 155, 2105-2112.
9. Chen H., Fernig D.G., Rudland P.S., Sparks A., Wilkinson M.C. and Barraclough R. (2001). Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka). Biochem. Biophys. Res. Commun. 286,1212-1217.
10. Davidson D.D. and Cheng L. (2006). "Field cancerization" in the urothelium of the bladder. Anal. Quant. Cytol. Histol. 28, 337-338.
11. Davies B.R., Davies M.P., Gibbs F.E., Barraclough R. and Rudland P.S. (1993). Induction of the metastatic phenotype by transfection of a benign rat mammary epithelial cell line with the gene for p9Ka, a rat calcium-binding protein, but not with the oncogene EJ-ras-1. Oncogene 8, 999-1008.
12. Davies B.R., O'Donnell M., Durkan G.C., Rudland P.S., Barraclough R., Neal D.E. and Mellon J.K. (2002). Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancer. J. Pathol. 196, 292-299.
13. Donato R. (1986). S-100 proteins. Cell Calcium 7,123-145.
14. Donato R. (1999). Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. Biochim. Biophys. Acta 1450, 191-231.
15. Donato R. (2003). Intracellular and extracellular roles of S100 proteins. Microsc. Res. Tech. 60, 540-551.
16. 2+ -binding protein family. Genes Dev. 3, 1086-1093.
17. Eckert R.L. and Lee K.C. (2006). S100A7 (Psoriasin): a story of mice and men. J. Invest. Dermatol. 126,1442-1444.
18. EL-Rifai W., Moskaluk C.A., Abdrabbo M.K., Harper J., Yoshida C., Riggins G.J., Frierson H.F. Jr and Powell S.M. (2002). Gastric cancers overexpress S100A calcium-binding proteins. Cancer Res. 62, 6823-6826.
19. Emberley E.D., Niu Y., Leygue E., Tomes L., Gietz R.D., Murphy L.C. and Watson P.H. (2003). Psoriasin interacts with Jab1 and influences breast cancer progression. Cancer Res. 63, 1954-1961.
20. Emerson R.E. and Cheng L. (2005). Immunohistochemical markers in the evaluation of tumors of the urinary bladder: a review. Anal. Quant. Cytol. Histol. 27, 301-316.
21. Fukuzawa H., Kiyoshima T., Kobayashi I., Ozeki S. and Sakai H. (2006). Transcription promoter activity of the human S100A7 gene in oral squamous cell carcinoma cell lines. Biochim. Biophys. Acts. 1759, 171-176.
22. Gebhardt C., Nemeth J., Angel P. and Hess J. (2006). S100A8 and S100A9 in inflammation and cancer. Biochem. Pharmacol. 14,14.
23. Gongoll S., Peters G., Mengel M., Piso P., Klempnauer J., Kreipe H. and von Wasielewski R. (2002). Prognostic significance of calcium-binding protein S100A4 in colorectal cancer. Gastroenterology 123, 1478-1484.
24. Grigorian M., Andresen S., Tulchinsky E., Kriajevska M., Carlberg C., Kruse C., Cohn M., Ambartsumian N., Christensen A., Selivanova G. and Lukanidin E. (2001). Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction. J. Biol. Chem. 276, 22699-22708.
25. Gupta S., Hussain T., MacLennan G.T., Fu P., Patel J. and Mukhtar H. (2003). Differential expression of S100A2 and S100A4 during progression of human prostate adenocarcinoma. J. Clin. Oncol. 21, 106-112.
26. Hsieh H.L., Schafer B.W., Sasaki N. and Heizmann C.W. (2003). Expression analysis of S100 proteins and RAGE in human tumors using tissue microarrays. Biochem. Biophys. Res. Commun. 307, 375-381.
27. Iczkowski K.A. and Butler S.L. (2006). New immunohistochemical markers in testicular tumors. Anal. Quant. Cytol. Histol. 28, 181-187.
28. Jemal A., Siegel R., Ward E., Murray T., Xu J., Smigal C. and Thun M.J. (2006). Cancer statistics, 2006. CA Cancer J. Clin. 56, 106-130.
29. Jenkinson S.R., Barraclough R., West C.R. and Rudland P.S. (2004). S100A4 regulates cell motility and invasion in an in vitro model for breast cancer metastasis. Br. J. Cancer 90, 253-262.
30. Jinquan T., Vorum H., Larsen C.G., Madsen P., Rasmussen H.H., Gesser B., Etzerodt M., Honore B., Celis J.E. and Thestrup-Pedersen K. (1996). Psoriasin: a novel chemotactic protein. J. Invest. Dermatol. 107, 5-10.
31. Knowles M.A. (1995). Molecular genetics of bladder cancer. Br. J. Urol. 1, 57-66.
32. Kriajevska M., Tarabykina S., Bronstein I., Maitland N., Lomonosov M., Hansen K., Georgiev G. and Lukanidin E. (1998). Metastasis-associated Mts1 (S100A4) protein modulates protein kinase C phosphorylation of the heavy chain of nonmuscle myosin. J. Biol. Chem. 273, 9852-9856.
33. Kriajevska M.V., Cardenas M.N., Grigorian M.S., Ambartsumian N.S., Georgiev G.P. and Lukanidin E.M. (1994). Non-muscle myosin heavy chain as a possible target for protein encoded by metastasis- related mts-1 gene. J. Biol. Chem. 269, 19679-19682.
34. Kroft S.H. and Oyasu R. (1994). Urinary bladder cancer: mechanisms of development and progression. Lab. Invest. 71, 158-174.
35. Krop I., Marz A., Carlsson H., Li X., Bloushtain-Qimron N., Hu M., Gelman R., Sabel M.S., Schnitt S., Ramaswamy S., Kleer C.G., Enerback C. and Polyak K. (2005). A putative role for psoriasin in breast tumor progression. Cancer Res. 65, 11326-11334.
36. Kyroudi-Voulgari A., Kouloukoussa M., Simigiatos C., Karakitsos P., Zervas A., Kittas C. and Mitropoulos D. (2005). DNA ploidy and immunomarking of bladder urothelial tumors before and after intravesical bacillus Calmette-Guerin treatment. Anal. Quant. Cytol. Histol. 27, 52-60.
37. Leven D., Flecknell P.A., Rudland P.S., Barraclough R., Neal D.E., Mellon J.K. and Davies B.R. (2062). Transfection of S100A4 produces metastatic variants of an orthotopic model of bladder cancer. Am. J. Pathol. 160, 693-700.
38. Li Z.H., Spektor A., Varlamova O. and Bresnick A.R. (2003). Mts1 regulates the assembly of nonmuscle myosin-IIA. Biochemistry 42, 14258-14266.
39. Lloyd B.H., Platt-Higgins A., Rudland P.S. and Barraclough R. (1998). Human S100A4 (p9Ka) induces the metastatic phenotype upon benign tumour cells. Oncogene 17, 465-473.
40. 2+ -relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray. Oncogene 23, 1291-1299.
41. Madsen P., Rasmussen H.H., Leffers H., Honore B., Dejgaard K., Olsen E., Kiil J., Walbum E., Andersen A.H., Besse B. and et al. (1991). Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin. J. Invest. Dermatol. 97, 701-712.
42. Makino E., Sakaguchi M., lwatsuki K. and Huh N.H. (2004). Introduction of an N-terminal peptide of S100C/A11 into human cells induces apoptotic cell death. J. Mol. Med. 82, 612-620.
43. Marenholz I., Heizmann C.W. and Fritz G. (2004). S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). Biochem. Biophys. Res. Commun. 322, 1111-1122.
44. Marenholz I., Lovering R.C. and Heizmann C.W. (2006). An update of the S100 nomenclature. Biochim. Biophys. Acta 26, 26.
45. Mazzucchelli R., Barbisan F., Stramazzotti D., Montironi R., Lopez-Beltran A. and Scarpelli M. (2005). Chromosomal abnormalities in macroscopically normal urothelium in patients with bladder pT1 and pT2a urothelial carcinoma: a fluorescence in situ hybridization study and correlation with histologic features. Anal. Quant. Cytol. Histol. 27, 143-151.
46. Melle C., Ernst G., Schimmel B., Bleul A., Mothes H., Kaufmann R., Settmacher U. and Von Eggeling F. (2006). Different expression of calgizzarin (S100A11) in normal colonic epithelium, adenoma and colorectal carcinoma. Int. J. Oncol. 28, 195-200.
47. Memon A.A., Sorensen B.S., Meldgaard P., Fokdal L., Thykjaer T. and Nexo E. (2005). Down-regulation of S100C is associated with bladder cancer progression and poor survival. Clin. Cancer Res. 11, 606-611.
48. Miyazaki M., Sakaguchi M., Akiyama I., Sakaguchi Y., Nagamod S. and Huh N.H. (2004). Involvement of interferon regulatory factor 1 and S1 00C/ A11 in growth inhibition by transforming growth factor beta 1 in human hepatocellular carcinoma cells. Cancer Res. 64, 4155-4161.
49. Nagy N., Brenner C., Markadieu N., Chaboteaux C., Camby I., Schafer B.W., Pachet R., Heizmann C.W., Salmon I., Kiss R. and Decaestecker C. (2001). S100A2, a putative tumor suppressor gene, regulates in vitro squamous cell carcinoma migration. Lab. Invest. 81, 599-612.
50. Ostergaard M., Rasmussen H.H., Nielsen H.V., Vorum H., Omtoft T.F., Wolf H. and Celis J.E. (1997). Proteome profiling of bladder squamous cell carcinomas: identification of markers that define their degree of differentiation. Cancer Res. 57, 4111-4117.
51. Ostergaard M., Wolf H., Omtoft T.F. and Celis J.E. (1999). Psoriasin (S100A7): a putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas. Electrophoresis 20, 349-354.
52. Reichling T., Goss K.H., Carson D.J., Holdcraft R.W., Loy-Ebert C., Witte D., Aronow B.J. and Groden J. (2005). Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors. Cancer Res. 65, 166-176.
53. 2+)-dependent association between S100C (S100A11) and its target, the N-terminal part of annexin I. Structure 8, 175-184.
54. Rudland P.S., Platt-Higgins A., Renshaw C., West C.R., Winstanley J.H., Robertson L. and Barraclough R. (20,00). Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancer. Cancer Res. 60, 1595-1603.
55. Sakaguchi M., Miyazaki M., Inoue Y., Tsuji T., Kouchi H., Tanaka T., Yamada H. and Namba M. (2000). Relationship between contact inhibition and intranuclear S100C of normal human fibroblasts. J. Cell Biol. 149, 1193-1206.
56. Sakaguchi M., Miyazaki M., Sonegawa H., Kashiwagi M., Ohba M., Kuroki T., Namba M. and Huh N.H. (2004). PKCalpha mediates TGFbeta-induced growth inhibition of human keratinocytes via phosphorylation of S100C/ A11. J. Cell Biol. 164, 979-984.
57. 21)-induced growth inhibition of human epidermal keratinocytes. J. Cell Biol. 163, 825-835.
58. Schmidt-Hansen B., Klingelhofer J., Grum-Schwensen B., Christensen A., Andresen S., Kruse C., Hansen T., Ambartsumian N., Lukanidin E. and Grigorian M. (2004a). Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay. J. Biol. Chem. 279, 24498-24504.
59. Schmidt-Hansen B., Omas D., Grigorian M., Klingelhofer J., Tulchinsky E., Lukanidin E. and Ambartsumian N. (2004b). Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity. Oncogene 23, 5487-5495.
60. Takenaga K., Nakamura Y., Sakiyama S., Hasegawa Y., Sato K. and Endo H. (1994). Binding of pEL98 protein, an S100-related calcium-binding protein, to nonmuscle tropomyosin. J. Cell Biol. 124, 757-768.
61. Takenaga K., Nakamura Y. and Sakiyama S. (1997). Expression of antisense RNA to S100A4 gene encoding an S100-related calcium-binding protein suppresses metastatic potential of high-metastatic Lewis lung carcinoma cells. Oncogene 14, 331-337.
62. Tolson J.P., Flad T., Gnau V., Dihazi H., Hennenlotter J., Beck A., Mueller G.A., Kuczyk M. and Mueller C.A. (2006). Differential detection of S100A8 in transitional cell carcinoma of the bladder by pair wise tissue proteomic and immunohistochemical analysis. Proteomics 6, 697-708.
63. Torres-Cabala C., Panizo-Santos A., Krutzsch H.C., Barazi H., Namba M., Sakaguchi M., Roberts D.D. and Merino M.J. (2004). Differential expression of S100C in thyroid lesions. Int. J. Surg. Pathol. 12, 107-115.
64. Watanabe Y., Usada N., Minami H., Morita T., Tsugane S., Ishikawa R., Kohama K., Tomida Y. and Hidaka H. (1993). Calvasculin, as a factor affecting the microfilament assemblies in rat fibroblasts transfected by src gene. FEBS Lett. 324, 51-55.
65. Yonemura Y., Endou Y., Kimura K., Fushida S., Bandou E., Taniguchi K., Kinoshita K., Ninomiya I., Sugiyama K., Heizmann C.W., Schafer B.W. and Sasaki T. (2000). Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer. Clin. Cancer Res. 6, 4234-4242.