Effects of intrathecal and i.v. small-dose sufentanil on the median effective dose of intrathecal bupivacaine for Caesarean section

British Journal of Anaesthesia

Volumn 98, Issue 6, 2007, Pages 792-796

  Wang, L Z ^a   Zhang, Y F ^a   Tang, B L ^a   Yao, K Z ^a  

^a Jiaxing Municipal No2 Hospital   (China)

Author keywords

Anaesthesia, obstetric; Anaesthetic techniques, regional; Anaesthetics local, bupivacaine; Pharmacology, sufentanil

Indexed keywords

ATROPINE; BUPIVACAINE; EPHEDRINE; HEMOGLOBIN; METOCLOPRAMIDE; OXYGEN; PLACEBO; RANITIDINE; SUFENTANIL; CENTRAL DEPRESSANT AGENT; LOCAL ANESTHETIC AGENT; NARCOTIC ANALGESIC AGENT;

ADULT; APGAR SCORE; ARTERIAL OXYGEN SATURATION; ARTICLE; BIRTH WEIGHT; BLOOD PH; BRADYCARDIA; CESAREAN SECTION; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SAFETY; ELECTIVE SURGERY; FEMALE; FREQUENCY ANALYSIS; GENERAL ANESTHESIA; HEMOGLOBIN DETERMINATION; HUMAN; HYPOTENSION; HYPOXEMIA; LOCAL ANESTHESIA; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MONOTHERAPY; NAUSEA AND VOMITING; OBSTETRIC ANESTHESIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; PRURITUS; RANDOMIZED CONTROLLED TRIAL; UMBILICAL CORD BLOOD; DRUG ADMINISTRATION; INTRASPINAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; PREGNANCY; SPINAL ANESTHESIA;

ADJUVANTS, ANESTHESIA; ADULT; ANALGESICS, OPIOID; ANESTHESIA, OBSTETRICAL; ANESTHESIA, SPINAL; ANESTHETICS, LOCAL; BUPIVACAINE; CESAREAN SECTION; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; INJECTIONS, SPINAL; PREGNANCY; PROSPECTIVE STUDIES; SUFENTANIL;

EID: 34447109232     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aem101     Document Type: Article

References (14)

1. Dahlgren G, Hultstrand C, Jakobsson J, Norman M, Eriksson EW, Martin H. Intrathecal sufentanil, fentanyl, or placebo added to bupivacaine for Cesarean section. Anesth Analg 1997; 85: 1288-93
2. Meininger D, Byhahn C, Kessler P, et al. Intrathecal fentanyl, sufentanil, or placebo combined with hyperbaric mepivacaine 2% for parturients undergoing elective cesarean delivery. Anesth Analg 2003; 96: 852-8
3. Braga Ade F, Braga FS, Poterio GM, Pereira RI, Reis E, Cremonesi E. Sufentanil added to hyperbaric bupivacaine for subarachnoid block in Caesarean section. Eur J Anaesthesiol 2003; 20: 631-5
4. Courtney MA, Bader AM, Hartwell B, Hauch M, Grennan MJ, Datta S. Perioperative analgesia with subarachnoid sufentanil administration. Reg Anesth Pain Med 1992; 17: 274-8
5. Fournier R, Weber A, Gamulin Z. Intrathecal sufentanil is more potent than intravenous for postoperative analgesia after total-hip replacement. Reg Anesth Pain Med 2005; 30: 249-54
6. Camann WR, Denney RA, Holby ED, Datta S. A comparison of intrathecal, epidural, and intravenous sufentanil for labor analgesia. Anesthesiology 1992; 77: 884-7
7. Ummenhofer WC, Arends RH, Shen DD, Bernards CM. Comparative spinal distribution and clearance kinetics of intrathecally administered morphine, fentanyl, alfentanil, and sufentanil. Anesthesiology 2000; 92: 739-53
8. Adam F, Le Bars D, Chauvin M, Guirimand F. Effects of intravenous and intrathecal sufentanil on a C-fibre reflex elicited by a wide range of stimulus intensities in the rat. Eur J Pharmacol 2001; 411: 93-106
9. Ferouz F, Norris MC, Arkoosh VA, Leighton BL, Boxer LM, Corba RJ. Baricity, needle direction, and intrathecal sufentanil labor analgesia. Anesthesiology 1997; 86: 592-8
10. Gage JC, D'Angelo R, Miller R. Eisenach JC. Does dextrose affect analgesia or the side effects of intrathecal sufentanil? Anesth Analg 1997; 85: 826-30
11. Dixon WJ, Massey FJ. Introduction to Statistical Analysis, 4th Edn. New York: McGraw-Hill, 1983; 428-39
12. Beale N, Evans B, Plaat F, Columb MO, Lyons G, Stocks GM. Effect of epidural volume extension on dose requirement of intrathecal hyperbaric bupivacaine at Caesarean section. Br J Anaesth 2005; 95: 500-3
13. Coda BA, Brown MC, Schaffer R, Donaldson G, Jacobson R, Hautman B, et al. Pharmacology of epidural fentanyl, alfentanil, and sufentanil in volunteers. Anesthesiology 1994; 81: 1149-61
14. Ginosar Y, Columb MO, Cohen SE, Mirikatani E, Tingle MS, Ratner EF, et al. The site of action of epidural fentanyl infusions in the presence of local anesthetics: A minimum local analgesic concentration infusion study in nulliparous labor. Anesth Analg 2003; 97: 1439-45