(2R,3S)-(+)- and (2S,3R)-(-)-Halofuginone lactate: Synthesis, absolute configuration, and activity against Cryptosporidium parvum

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 15, 2007, Pages 4140-4143

  Linder, Michael R ^a   Heckeroth, Anja R ^a   Najdrowski, Michael ^b   Daugschies, Arwid ^b   Schollmeyer, Dieter ^c   Miculka, Christian ^a  

^a Intervet Innovation GmbH   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Anti protozoal; Chiral switch; Cryptosporidium parvum; Halofuginone

Indexed keywords

HALOFUGINONE LACTATE;

ARTICLE; CRYPTOSPORIDIUM PARVUM; DRUG SYNTHESIS; ENANTIOMER; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; RACEMIC MIXTURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIPROTOZOAL AGENTS; CRYPTOSPORIDIUM PARVUM; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; QUINAZOLINONES; STEREOISOMERISM;

CRYPTOSPORIDIUM PARVUM;

EID: 34447106342     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.053     Document Type: Article

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