Microbial hydroxylation of 16α,17α-dimethyl-17β-(l-oxopropyl)androsta-l,4-dien-3-one to rimexolone by Curvularia lunata AS 3.4381

Journal of Molecular Catalysis B: Enzymatic

Volumn 47, Issue 3-4, 2007, Pages 155-158

  Yang, Jiong ^a   Yang, Shunkai ^b   Yang, Ya Li ^b   Zheng, Hu ^a   Weng, Lingling ^a   Liu, Luo ^a  

^a SICHUAN UNIVERSITY   (China)

^b CHENGDU INSTITUTE OF BIOLOGY   (China)

Author keywords

Biotransformation; Curvularia lunata AS 3.4381; Rimexolone; Steroid 11 hydroxylation

Indexed keywords

BIOTRANSFORMATION; CURVULARIA LUNATA; INTRAOCULAR PRESSURE; RIMEXOLONE;

CHEMICAL ANALYSIS; FLAMMABILITY; HYDROXYLATION; INFRARED SPECTROSCOPY; MICROORGANISMS; NUCLEAR MAGNETIC RESONANCE;

KETONES;

16ALPHA,17ALPHA DIMETHYL 17BETA (1 OXOPROPYL)ANDROSTA 1,4 DIEN 3 ONE; ANDROSTANE DERIVATIVE; RIMEXOLONE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; CURVULARIA LUNATA; DRUG SYNTHESIS; FUNGAL STRAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MICROBIAL ACTIVITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEROID HYDROXYLATION; THIN LAYER CHROMATOGRAPHY;

COCHLIOBOLUS LUNATUS;

EID: 34447105432     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcatb.2007.05.001     Document Type: Article

References (11)

1. J.J. Boltralik, US Patent 4,686,214 (1987).
2. Assil K.K. J. Cataract. Refract. Surg. 23 (1997) 750
3. Bron A. Eur. J. Ophthalmol. 8 (1998) 16
4. Foster S. Am. J. Ophthalmol. 122 (1996) 171
5. Leibowitz H.M. Arch. Ophthalmol. 114 (1996) 933
6. Conrow R.E. J. Org. Chem. 64 (1999) 1042
7. Peterson D.H., Murray H.C., and Eppstein S.H. J. Am. Chem. Soc. 74 (1952) 5933
8. Holland H.L. Chem. Soc. Rev. 11 (1982) 371
9. G.F. Woods, J. Cairns, G. McGary, US Patent 3,862,194 (1975).
10. M.J. O'Neil (Senior Ed.), et al., The Merck Index, 13th ed., Merck Research Laboratories Division of Merck & Co., Inc., Whitehouse Station, NJ, 2001 (on CD-ROM).
11. Cairns J., Logan R.T., McGary G., et al. J. Chem. Soc., Perkin Trans. I (1981) 2306