Systematic errors and susceptibility to noise of four methods for calculating anatomical dead space from the CO2 expirogram

British Journal of Anaesthesia

Volumn 98, Issue 6, 2007, Pages 828-834

  Tang, Y ^a   Turner, M J ^a   Baker, A B ^a  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Airway, dead space; Carbon dioxide, measurement; Lung, dead space

Indexed keywords

CARBON DIOXIDE; OXYGEN;

ADULT; AGED; ARTICLE; CALCULATION; CLINICAL ARTICLE; CONTROLLED STUDY; EXHALATION; HUMAN; LUNG ALVEOLUS; LUNG DEAD SPACE; MEASUREMENT; NOISE; PRIORITY JOURNAL; SPIROGRAPHY; SYSTEMATIC ERROR; BIOLOGICAL MODEL; BLOOD; CAPNOGRAPHY; LUNG GAS EXCHANGE; METHODOLOGY; MIDDLE AGED; MONTE CARLO METHOD; PHYSIOLOGY; TIDAL VOLUME;

AGED; CAPNOGRAPHY; CARBON DIOXIDE; HUMANS; MIDDLE AGED; MODELS, BIOLOGICAL; MONTE CARLO METHOD; OXYGEN; PULMONARY GAS EXCHANGE; RESPIRATORY DEAD SPACE; TIDAL VOLUME;

EID: 34447103117     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aem090     Document Type: Article

References (30)

1. Kline JA, Israel EG, Michelson EA, et al. Diagnostic accuracy of a bedside D-dimer assay and alveolar dead-space measurement for rapid exclusion of pulmonary embolism: A multicenter study. JAMA 2001; 285: 761-8
2. Kline JA, Kubin AK, Patel MM, Easton EJ, Seupal RA. Alveolar dead space as a predictor of severity of pulmonary embolism. Acad Emerg Med 2000; 7: 611-7
3. Noble MI, Langley F, Buckman M, et al. Comparison of ventilation/ perfusion lung-imaging and dead-space measurements in airway disease. Clin Sci (Lond) 1981; 60: 17-23
4. Tang Y, Turner MJ, Baker AB. Effects of alveolar dead-space, shunt and V/ Q distribution on respiratory dead-space measurements. Br J Anaesth 2005; 95: 538-48
5. Severinghaus JW, Stupfel M. Alveolar dead space. Am J Physiol 1955; 183: 660
6. Fowler WS. Lung function studies. II: The respiratory dead space. Am J Physiol 1948; 154: 405-16
7. Hatch T, Cook KM, Palm PE. Respiratory dead space. J Appl Physiol 1953; 5: 341-7
8. Langley F, Even P, Duroux P, Nicolas RL, Cumming G. Ventilatory consequences of unilateral pulmonary artery occlusion. Coll Inst Natl Sante Rech Med 1975; 51: 209-12
9. Fletcher R, Jonson B, Cumming G, Brew J. The concept of dead-space with special reference to the single breath test for carbon dioxide. Br J Anaesth 1981; 53: 77-88
10. Cumming G, Guyatt AR. Alveolar gas mixing efficiency in the human lung. Clin Sci (Lond) 1982; 62: 541-7
11. Wolff G, Brunner JX, Weibel W, Bowes R, Bertschmann MW. Anatomical and series dead space volume: Concept and measurement in clinical praxis. Appl Cardiopulm Pathophysiol 1989; 2: 299-307
12. Bowes CL, Richardson JD, Cumming G, Horsfield K. Effect of breathing pattern on gas mixing in a model with asymmetrical alveolar ducts. J Appl Physiol 1985; 58: 18-26
13. Raemer DB, Calalang I. Accuracy of end-tidal carbon dioxide tension analyzers. J Clin Monit 1991; 7: 195-208
14. 2, and Christian Bohr. Acta Anaesthesiol Scand 1984; 28: 408-11
15. Fletcher R, Jonson B. Deadspace and the single breath test for carbon dioxide during anaesthesia and artificial ventilation. Effects of tidal volume and frequency of respiration. Br J Anaesth 1984; 56: 109-19
16. Wolff G, Brunner JX. Series dead space volume assessed as the mean value of a distribution function. Int J Clin Monit Comput 1984; 1: 177-81
17. Ream RS, Schreiner MS, Neff JD, et al. Volumetric capnography in children. Influence of growth on the alveolar plateau slope. Anesthesiology 1995; 82: 64-73
18. De Robertis E, Servillo G, Jonson B, Tufano R. Aspiration of dead space allows normocapnic ventilation at low tidal volumes in man. Intensive Care Med 1999; 25: 674-9
19. Williams EM, Hamilton RM, Sutton L, Viale JP, Hahn CE. Alveolar and dead space volume measured by oscillations of inspired oxygen in awake adults. Am J Respir Crit Care Med 1997; 156: 1834-9
20. Breen PH, Mazumdar B, Skinner SC. Comparison of end-tidal PCO2 and average alveolar expired PCO2 during positive end-expiratory pressure. Anesth Analg 1996; 82: 368-73
21. Mathworks. Signal Processing Toolbox-user's Guide. Natick, MA: The Math Works Inc., 2004
22. 2): an indicator gas for phase II in expirograms. J Appl Physiol 2004; 97: 1755-62
23. Tang Y, Turner MJ, Yem JS, Baker AB. Calibration of pneumotachographs using a calibrated syringe. J Appl Physiol 2003; 95: 571-6
24. Baker AB, Colliss JE, Cowie RW. Effects of varying inspiratory flow waveform time in intermittent positive pressure ventilation. II: Various physiological variables. Br J Anaesth 1977; 49: 1221-34
25. Williams MH, Jr, Rayford CM. Effect of variation of tidal volume on size of physiological dead space in dogs. J Appl Physiol 1956; 9: 30-2
26. Dixon WJ, Massey FJ. Introduction to Statistical Analysis, 4th edn. New York: McGraw-Hill, 1983
27. Astrom E, Niklason L, Drefeldt B, Bajc M, Jonson B. Partitioning of dead space - a method and reference values in the awake human. Eur Respir J 2000; 16: 659-64
28. 2 analyzer. Br J Anaesth 1980; 52: 491-9
29. Romero PV, Lucangelo U, Lopez Aguilar J, Fernandez R, Blanch L. Physiologically based indices of volumetric capnography in patients receiving mechanical ventilation. Eur Respir J 1997; 10: 1309-15
30. 2SMO monitor. Intensive Care Med 2004; 30: 1461-7