Effect of adenosine A1 receptor antagonist on learning and memory and analysis of its mechanism

Yaoxue Xuebao

Volumn 38, Issue 6, 2003, Pages 416-419

  Zhang, Dan Shen ^a,b   Ren, Lei Ming ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Zhangjiakou Medical College   (China)

Author keywords

2 amino 5 phosphonovaleric; 8 cyclopentyl 1, 3 dipropylxanthine; Acetylcholinesterase; Adenosine A1 receptor; GABA; Glutamate; Memory

Indexed keywords

1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE; 2 AMINO 5 PHOSPHONOVALERIC ACID; 4 AMINOBUTYRIC ACID; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ACETYLCHOLINE; ADENOSINE A1 RECEPTOR; GLUTAMIC ACID; SCOPOLAMINE; XANTHINE DERIVATIVE;

ANIMAL; ARTICLE; BRAIN; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; LEARNING; MALE; METABOLISM; MOUSE; RANDOMIZATION;

2-AMINO-5-PHOSPHONOVALERATE; ACETYLCHOLINE; ANIMALS; BRAIN; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; LEARNING; MALE; MICE; RANDOM ALLOCATION; RECEPTOR, ADENOSINE A1; SCOPOLAMINE; XANTHINES;

EID: 3442895449     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Zhang SS, Zhang L, Zhang DS. Cerebral glutamate/GABA system to regulate learning and memory [J]. Acta Pharm Sin, 1997, 32(8):638-640.
2. Tang YP. Central cholinergic mechanism of learning and memory [J]. Chin Pharmacol Bull, 1993, 9(2):85-89.
3. 1 receptors in the posterior cingulate cortex facilitates memory in rats [J]. Eur J Pharmacol, 2002, 437(3):151-154.
4. Sun MK, Xu H, Alkon DL. Pharmacological protection of synaptic function spatial learning and memory from transient hypoxia in rats [J]. J Pharmacol Exp Ther, 2002, 300(2):408-416.
5. Olney JW, Labruyere J, Wang G, et al. NMDA antagonist neurotoxicity: mechanism and prevention [J]. Science, 1991, 254(3):1515-1518.
6. Shen LX, Zhang DS, Zhang L, et al. Action of osthol on learning and memory and its mechanism analysis [J]. Acta Pharm Sin, 1999, 34(6):405-409.
7. Chen Q. Experiment Method of Study on Antisenility [M]. Beijing: China Medico-Pharmaceutical Science and Technology Publishing House, 1996. 108-110.
8. Koles L, Wirkner K, Illes P. Modulation of ionotropic glutamate receptor channels [J]. Neurochem Res, 2001, 26(8-9):925-932.
9. Zhang DS, Xue GP, Zhang L, et al. Effect of intracerebroventricular injection of N-methyl-D-aspartate on learning and memory in mice [J]. Acta Pharm Sin, 1993, 28(5):321-325.
10. 5 impairs performance on a non-spatial operant DRL task in the rat [J]. Exp Brain Res, 1988, 73(1):181-188.
11. Shen FM, Chu ZX, Su DF. The cardiovascular effect of adenosine [A]. Wang YM, Su DF. Advance in Pharmacology [M]. Beijing: Science Press, 2000. 54-60.
12. Tchekalarova J, Kambourova T, Georgiev V. Interaction of angiotensin II and III with A(1) receptor-related drugs in passive avoidance conditioning in rat [J]. Behav Brain Res, 2002, 129(1-2):61-64.
13. Homayoun H, Khavandgar S, Zarrindast MR. Effects of adenosine receptor agonists and antagonists on pentylenetetrazole-induced amnesia [J]. Eur J Pharmacol, 2001, 430(2-3):289-294.
14. 2 receptor blockade on spatial memory performance of rats: selective enhancement of reference memory retention during the light period [J]. Behav Brain Res, 2001, 118(1):43-52.
15. 1 receptor-mediated impairment of passive avoidance performance and long-term potentiation in the hippocampus [J]. Biol Pharm Bull, 2001, 24(5):496-500.
16. Assi AA. N6-cyclohexyladenosine and 3-(2-carboxypiperazine-4-yl)-1- propenyl-1-phosphonic acid enhance the effect of antiepileptic drugs against induced seizures in mice [J]. J Pharm Pharm Sci, 2001, 4(1):42-51.