APC derived from donor splenocytes support retinal autoimmune disease in allogeneic recipients

Journal of Leukocyte Biology

Volumn 76, Issue 2, 2004, Pages 383-387

  Gregerson, Dale S ^a   Kawashima, Hidetoshi ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b SAITAMA RED CROSS HOSPITAL   (Japan)

Author keywords

Antigen presentation; Arrestin; Autoimmunity; T cells; Uveoretinitis

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALLERGIC ENCEPHALOMYELITIS; ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; AUTOIMMUNE DISEASE; BONE MARROW TRANSPLANTATION; CELL FUNCTION; CELL TRANSFER; CHIMERA; CONFERENCE PAPER; CONTROLLED STUDY; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN CELL; T LYMPHOCYTE; UVEORETINITIS;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN-PRESENTING CELLS; BONE MARROW; COCULTURE TECHNIQUES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; RATS; SPLEEN;

ANIMALIA;

EID: 3442886199     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0404249     Document Type: Conference Paper

References (26)

1. Roberge, F. G., Caspi, R. R., Nussenblatt, R. B. (1988) Glial retinal Muller cells produce IL-1 activity and have a dual effect on autoimmune T helper lymphocytes. Antigen presentation manifested after removal of suppressive activity. J. Immunol. 140, 2193-2196.
2. Fujikawa, L. S., Chan, C. C., McAllister, C., Gery, I., Hooks, J. J., Detrick, B., Nussenblatt, R. B. (1987) Retinal vascular endothelium expresses fibronectin and class II histocompatibility complex antigens in experimental autoimmune uveitis. Cell. Immunol. 106, 139-150.
3. Lightman, S., Palestine, A., Nussenblatt, R. (1987) Intraocular la experimental in vivo induced in the absence of immune T cells. Cell. Immunol. 106, 242-249.
4. Sun, D., Wekerle, H. (1986) Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes. Nature 320, 70-72.
5. Hickey, W., Kimura, H. (1988) Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 239, 290-292.
6. Hinrichs, D., Wegmann, K., Dietsch, G. (1987) Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element. J. Exp. Med. 166, 1906-1911.
7. Ishimoto, S., Zhang, J., Gullapalli, V. K., Pararajasegaram, G., Rao, N. A. (1998) Antigen-presenting cells in experimental autoimmune uveoretinitis. Exp. Eye Res. 67, 539-548.
8. Gregerson, D. S., Sam, T. N., McPherson, S. W. (2004) The antigen presenting activity of fresh, adult parenchymal microglia and perivascular cells from retina. J. Immunol. 172, 6587-6597.
9. Gregerson, D. S., Obritsch, W. F., Fling, S. P., Cameron, J. D. (1986) S-antigen-specific rat T cell lines recognize peptide fragments of S-antigen and mediate experimental autoimmune uveoretinitis and pinealitis. J. Immunol. 136, 2875-2882.
10. Merryman, C. F., Donoso, L. A., Zhang, X. M., Heber-Katz, E., Gregerson, D. S. (1991) Characterization of a new, potent, immunopathogenic epitope in S-antigen that elicits T cells expressing V β 8 and V α 2-like genes. J. Immunol. 146, 75-80.
11. van Gelder, M., Kinwel-Bohre, E. P., Mulder, A. H., van Bekkum, D. W. (1996) Both bone marrow- and non-bone marrow-associated factors determine susceptibility to experimental autoimmune encephalomyelitis of BUF and WAG rats. Cell. Immunol. 168, 39-48.
12. Hirose, S., Ogasawara, K., Natori, T., Sasamoto, Y., Ohno, S., Matsuda, H., Onoe, K. (1991) Regulation of experimental autoimmune uveitis in rats-separation of MHC and non-MHC gene effects. Clin. Exp. Immunol. 86, 419-425.
13. Gregerson, D. S., Yang, J. (2003) CD45-positive cells of the retina and their responsiveness to in vivo and in vitro treatment with IFN-γ or anti-CD40. Invest. Ophthalmol. Vis. Sci. 44, 3083-3093.
14. Prendergast, R. A., Iliff, C. E., Coskuncan, N. M., Caspi, R. R., Sartani, G., Tarrant, T. K., Lutty, G. A., McLeod, D. S. (1998) T cell traffic and the inflammatory response in experimental autoimmune uveoretinitis. Invest. Ophthalmol. Vis. Sci. 39, 754-762.
15. Hu, P., Pollard, J. D., Chan-Ling, T. (2000) Breakdown of the blood-retinal barrier induced by activated T cells of nonneural specificity. Am. J. Pathol. 156, 1139-1149.
16. Flugel, A., Bradl, M., Kreutzberg, G. W., Graeber, M. B. (2001) Transformation of donor-derived bone marrow precursors into host microglia during autoimmune CNS inflammation and during the retrograde response to axotomy. J. Neurosci. Res. 66, 74-82.
17. Randolph, G. J., Sanchez-Schmitz, G., Liebman, R. M., Schakel, K. (2002) The CD16(+) (FcγRIII(+)) subset of human monocytes preferentially becomes migratory dendritic cells in a model tissue setting. J. Exp. Med. 196, 517-527.
18. Myers, K. J., Dougherty, J. P., Ron, J. (1993) In vivo antigen presentation by both brain parenchymal cells and hematopoietically derived cells during the induction of experimental autoimmune encephalomyelitis. J. Immunol. 151, 2252-2260.
19. Li, Y. Q., Chen, P., Haimovitz-Friedman, A., Reilly, R. M., Wong, C. S. (2003) Endothelial apoptosis initiates acute blood-brain barrier disruption after ionizing radiation. Cancer Res. 63, 5950-5956.
20. Li, Y. Q., Chen, P., Jain, V., Reilly, R. M., Wong, C. S. (2004) Early radiation-induced endothelial cell loss and blood-spinal cord barrier breakdown in the rat spinal cord. Radiat. Res. 161, 143-152.
21. Gaber, M. W., Sabek, O. M., Fukatsu, K., Wilcox, H. G., Kiani, M. F., Merchant, T. E. (2003) Differences in ICAM-1 and TNF-α expression between large single fraction and fractionated irradiation in mouse brain. Int. J. Radiat. Biol. 79, 359-366.
22. Olschowka, J. A., Kyrkanides, S., Harvey, B. K., O'Banion, M. K., Williams, J. P., Rubin, P., Hansen, J. T. (1997) ICAM-1 induction in the mouse CNS following irradiation. Brain Behav. Immun. 11, 273-285.
23. Kiani, M. F., Yuan, H., Chen, X., Smith, L., Gaber, M. W., Goetz, D. J. (2002) Targeting microparticles to select tissue via radiation-induced upregulation of endothelial cell adhesion molecules. Pharm. Res. 19, 1317-1322.
24. Gaber, M.W., Yuan, H., Killmar, J.T., Naimark, M.D., Kiani, M.F., Merchant, T.E. (2004) An intravital microscopy study of radiation-induced changes in permeability and leukocyte-endothelial cell interactions in the microvessels of the rat pia mater and cremaster muscle. 13, 1-10.
25. Yuan, H., Gaber, M. W., McColgan, T., Naimark, M. D., Kiani, M. F., Merchant, T. E. (2003) Radiation-induced permeability and leukocyte adhesion in the rat blood-brain barrier: modulation with anti-ICAM-1 antibodies. Brain Res. 969, 59-69.
26. McMenamin, P. G., Wealthall, R. J., Deverall, M., Cooper, S. J., Griffin, B. (2003) Macrophages and dendritic cells in the rat meninges and choroid plexus: three-dimensional localisation by environmental scanning electron microscopy and confocal microscopy. Cell Tissue Res. 313, 259-269.