Can we restore aspects of the in utero environment in premature infants to prevent disease?

Pediatrics

Volumn 114, Issue 2 I, 2004, Pages 491-

  Smith, Lois E H ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C;

CHILD GROWTH; FETUS DEVELOPMENT; FETUS GROWTH; HUMAN; INFANT; NOTE; PREMATURITY; PREVENTIVE MEDICINE; PRIORITY JOURNAL; RETROLENTAL FIBROPLASIA;

HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INSULIN-LIKE GROWTH FACTOR I; RETINOPATHY OF PREMATURITY;

EID: 3442878106     PISSN: 00314005     EISSN: None     Source Type: Journal    
DOI: 10.1542/peds.114.2.491     Document Type: Note

References (5)

1. Hellstrom A, Engstrom E, Hard AL, et al. Postnatal serum insulin-like growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth. Pediatrics. 2003;112:1016-100
2. Smith LE, Shen W, Perruzzi C, et al. Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor. Nat Med. 1999;5:1390-1395
3. Smith LE. Pathogenesis of retinopathy of prematurity. Acta Paediatr Suppl. 2002;91:26-28
4. Hellstrom A, Perruzzi C, Ju M, et al. Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity. Proc Natl Acad Sci U S A. 2001;98: 5804-5808
5. Hellstrom A, Carlsson B, Niklasson A, et al. IGF-I is critical for normal vascularization of the human retina. J Clin Endocrinol Metab. 2002;87: 3413-3416