Antifertility effect of aqueous and ethanol extracts of the leaves and roots of Asparagus africanus in rats

African Health Sciences

Volumn 6, Issue 2, 2006, Pages 81-85

  Tafesse, Geremew ^a   Mekonnen, Yalemtsehay ^b   Makonnen, Eyasu ^c  

^a Debub University   (Ethiopia)

^b ADDIS ABABA UNIVERSITY   (Ethiopia)

^c ADDIS ABABA UNIVERSITY   (Ethiopia)

Author keywords

Anti implantation; Antifertility; Aqueous extract; Asparagus africanus; Ethanol extract; Leaves; Rats; Roots

Indexed keywords

ACETYLCHOLINE; ALCOHOL; ASPARAGUS AFRICANUS EXTRACT; CONTRACEPTIVE AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

ANGIOSPERM; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; ASPARAGUS AFRICANUS; CONCENTRATION RESPONSE; CONTRACEPTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; ETHIOPIA; FEEDING; FEMALE; HORMONAL REGULATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PLANT LEAF; PLANT ROOT; RAT; UTERUS CONTRACTION;

ANALYSIS OF VARIANCE; ANIMALS; ASPARAGUS PLANT; CONTRACEPTIVE AGENTS; DISEASE MODELS, ANIMAL; ETHANOL; FEMALE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANT ROOTS; PREGNANCY; PREGNANCY, ANIMAL; PROBABILITY; RANDOM ALLOCATION; RATS; RATS, WISTAR; SENSITIVITY AND SPECIFICITY; UTERINE CONTRACTION; UTERUS;

EID: 34347407172     PISSN: 16806905     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Demissew, S. (1997). Asparagaceae: In flora of Ethiopia and Eritrea. (Eds. Edward, S., Demissew, S. and Hedberg, I.), 6: 67-69.
2. Kokowaro, J. O. Asparagus africanus. Medicinal plants of East Africa. 1976; p. 239
3. Mungai, G. M. Some medicinal plants of Amboseli National Park and their uses: In conservation and utilization of indigenous medicinal plants and wild relatives of food crops. 1997; pp. 53-56
4. Gashaw, M. The use and value of wild plants to the people of Bale. Walia, 1991; 18: 21-28
5. Debella, A., Haslinger, E., Kunert, O., Michl, G. & Dawit Abebe. Steroidal saponins from Asparagus africanus. Phytochemistry 1999;51:1066-1075
6. Yu-Shao, Poobraster, O., Kennelly, E. J., Chi-Tang, H., Havang, M., Garrison, S. A. and Cordell, G. A. Steriodal saponins from Asparagus officinalis and their cytotocic effect. Planta Medica, 1997; 63: 258-26
7. Desta, B. Ethiopian traditional herbal drugs. Part III: Anti-fertility activity of 70 medicinal plants. Journal of Ethnopharmacol. 1994;44:199-209.
8. Uguru, M. O., Okwuasaba, F. K., Ekwenchi, M. M. and Uguru, V. E. Oxytocic and oestrogenic effects of Monechma ciliatum methanol extract in vivo and in vitro in rodents. Phytotherpay Research, 1995;9:26-29
9. Williamson, E. M., Okpako, D. T. and Evan, F. G. Selection, preparation and pharmacological evaluation of plant material. Pharmacological Methods in Phytotherapy Research, 1996;1:191-212
10. Mekonnen, Y. Effects of ethanol extract of Moringa stenopetala leaves on guinea pig and mouse smooth muscle. Phytotherapy Research, 1999;13:442-444
11. Woo, W. S., Lee, E. B., Kang, S. S., Shin, K. H. and Chi, H. J. Antifertility principle of Dictamnus albus root bark. Planta Medica, 1987;53:399-401
12. Fransworth, M. R., Bingel, A. S., Cordell, G. A., Crane, F. A. and Fong, H. S. Potential value of plants as sources of new anti-fertility agent I. Journal of Pharmaceutical Science, 1975;64:535-598
13. Goldfien, A. The gonadal hormones and inhibitors. Basic and clinical pharmacology, 6th ed. (ed. Katzung, B. G.). Appleton and Lange, 25 Van Zant Street, East Norwalk. 1995;pp.608-636
14. Makonnen, E., Amr A.H. Rostom, Legesse Zerihun, and Getachew Assefa: Effect of Ricinus communis and Jatropha curcas seeds on uterine muscle of guinea pigs. Egyptian Journal of Medical Laboratory Sciences. 1998;7:93-101