Lack of effect of acute enteral arginine infusion on whole-body and intestinal protein metabolism in humans

Digestive Diseases and Sciences

Volumn 52, Issue 8, 2007, Pages 1826-1832

  Claeyssens, Sophie ^a   Lecleire, Stéphane ^a,b   Leblond, Jonathan ^a   Marion, Rachel ^a   Hecketsweiler, Bernadette ^a   Lavoinne, Alain ^a   Ducrotté, Philippe ^a   Déchelotte, Pierre ^a   Coëffier, Moïse ^a  

^a INSERM   (France)

^b ROUEN UNIVERSITY HOSPITAL   (France)

Author keywords

Amino acid; Intestine; Protein synthesis; Proteolysis; Stable isotope

Indexed keywords

ARGININE; CALPAIN; CATHEPSIN D; LEUCINE; MESSENGER RNA; STABLE ISOTOPE; UBIQUITIN;

ADULT; ARTICLE; DUODENUM BIOPSY; DUODENUM MUCOSA; FEMALE; GAS CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; MALE; MASS SPECTROMETRY; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILCOXON SIGNED RANKS TEST;

ADULT; AMINO ACIDS; ARGININE; CALPAIN; CARBON RADIOISOTOPES; CATHEPSINS; DUODENUM; FEMALE; HUMANS; INTESTINAL MUCOSA; INTESTINES; LEUCINE; MALE; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UBIQUITIN;

EID: 34347403237     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-9628-9     Document Type: Article

References (33)

1. Nieves C Jr, Langkamp-Henken B (2002) Arginine and immunity: a unique perspective. Biomed Pharmacother 56:471-482
2. de Jonge WJ, Kwikkers KL, te Velde AA, van Deventer SJ, Nolte MA, Mebius RE, Ruijter JM, Lamers MC, Lamers WH (2002) Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice. J Clin Invest 110:1539-1548
3. Wu G, Morris SM Jr (1998) Arginine metabolism: nitric oxide and beyond. Biochem J 336:1-17
4. Lecleire S, Coëffier M, Leblond J, Lemoulan S, Hubert A, Petit A, Ducrotté P, Déchelotte P, Marion R (2005) Modulation of nitric oxide and cytokines production by L-arginine in human gut mucosa. Clin Nutr 24:353-359
5. Marion R, Coeffier M, Lemoulan S, Gargala G, Ducrotte P, Dechelotte P (2005) L-Arginine modulates CXC chemokines in the human intestinal epithelial cell line HCT-8 by the NO pathway. Biochimie 87:1048-1055
6. Wu G, Meininger CJ, Knabe DA, Bazer FW, Rhoads JM (2000) Arginine nutrition in development, health and disease. Curr Opin Clin Nutr Metab Care 3:59-66
7. Barbul A, Lazarou SA, Efron DT, Wasserkrug HL, Efron G (1990) Arginine enhances wound healing and lymphocyte immune responses in humans. Surgery 108:331-336, discussion 336-337
8. Di Lorenzo M, Bass J, Krantis A (1995) Use of L-arginine in the treatment of experimental necrotizing enterocolitis. J Pediatr Surg 30:235-240, discussion 240-241
9. Chung DH, Evers BM, Townsend CM Jr, Huang KF, Herndon DN, Thompson JC (1993) Role of polyamine biosynthesis during gut mucosal adaptation after burn injury. Am J Surg 165:144-149
10. Minuskin ML, Lavine ME, Ulman EA, Fisher H (1981) Nitrogen retention, muscle creatine and orotic acid excretion in traumatized rats fed arginine and glycine enriched diets. J Nutr 111:1265-1274
11. Merimee TJ, Lillicrap DA, Rabinowitz D (1965) Effect of arginine on serum-levels of human growth-hormone. Lancet 2:668-670
12. Woolfson AM, Heatley RV, Allison SP (1979) Insulin to inhibit protein catabolism after injury. N Engl J Med 300:14-17
13. Takagi K, Tashiro T, Yamamori H, Mashima Y, Nakajima N, Sunaga K (1995) Recombinant human growth hormone and protein metabolism of burned rats and esophagectomized patients. Nutrition 11:22-26
14. Sitren HS, Fisher H (1977) Nitrogen retention in rats fed on diets enriched with arginine and glycine. 1. Improved N retention after trauma. Br J Nutr 37:195-208
15. Bruins MJ, Soeters PB, Lamers WH, Deutz NE (2002) L-Arginine supplementation in pigs decreases liver protein turnover and increases hindquarter protein turnover both during and after endotoxemia. Am J Clin Nutr 75:1031-1044
16. Cui XL, Iwasa M, Iwasa Y, Ohmori Y, Yamamoto A, Maeda H, Kume M, Ogoshi S, Yokoyama A, Sugawara T, Funada T (1999) Effects of dietary arginine supplementation on protein turnover and tissue protein synthesis in scald-burn rats. Nutrition 15:563-569
17. Leon P, Redmond HP, Stein TP, Shou J, Schluter MD, Kelly C, Lanza-Jacoby S, Daly JM (1991) Arginine supplementation improves histone and acute-phase protein synthesis during gram-negative sepsis in the rat. J Parenter Enteral Nutr 15:503-508
18. Wakabayashi Y, Yamada E, Yoshida T, Takahashi H (1994) Arginine becomes an essential amino acid after massive resection of rat small intestine. J Biol Chem 269:32667-32671
19. Adegoke OA, McBurney MI, Samuels SE, Baracos VE (2003) Modulation of intestinal protein synthesis and protease mRNA by luminal and systemic nutrients. Am J Physiol Gastrointest Liver Physiol 284:G1017-G1026
20. Coeffier M, Claeyssens S, Hecketsweiler B, Lavoinne A, Ducrotte P, Dechelotte P (2003) Enteral glutamine stimulates protein synthesis and decreases ubiquitin mRNA level in human gut mucosa. Am J Physiol Gastrointest Liver Physiol 285:G266-G273
21. Bouteloup-Demange C, Boirie Y, Dechelotte P, Gachon P, Beaufrere B (1998) Gut mucosal protein synthesis in fed and fasted humans. Am J Physiol 274:E541-E546
22. Bouteloup-Demange C, Claeyssens S, Maillot C, Lavoinne A, Lerebours E, Dechelotte P (2000) Effects of enteral glutamine on gut mucosal protein synthesis in healthy humans receiving glucocorticoids. Am J Physiol Gastrointest Liver Physiol 278:G677-G681
23. Claeyssens S, Bouteloup-Demange C, Gachon P, Hecketsweiler B, Lerebours E, Lavoinne A, Déchelotte P (2000) Effect of enteral glutamine on leucine, phenylalanine and glutamine metabolism in hypercortisolemic subjects. Am J Physiol Endocrinol Metab 278:E817-E824
24. Nakshabendi IM, Downie S, Russell RI, Rennie MJ (1996) Increased rates of duodenal mucosal protein synthesis in vivo in patients with untreated coelia disease. Gut 39:176-179
25. Rennie MJ, Edwards RH, Halliday D, Matthews DE, Wolman SL, Millward DJ (1982) Muscle protein synthesis measured by stable isotope techniques in man: the effects of feeding and fasting. Clin Sci (Lond) 63:519-523
26. Gianotti L, Braga M, Nespoli L, Radaelli G, Beneduce A, Di Carlo V (2002) A randomized controlled trial of preoperative oral supplementation with a specialized diet in patients with gastrointestinal cancer. Gastroenterology 12:1763-1770
27. Ishibashi Y, Hanyu N, Suzuki Y, Yanai S, Tashiro K, Usuba T, Iwabuchi S, Takahashi T, Takada K, Ohkawa K, Urashima M, Yanaga K (2004) Quantitative analysis of free ubiquitin and multi-ubiquitin chain in colorectal cancer. Cancer Lett 211:111-117
28. Lakshmikuttyamma A, Selvakumar P, Kanthan R, Kanthan SC, Sharma RK (2004) Overexpression of m-calpain in human colorectal adenocarcinomas. Cancer Epidemiol Biomarkers Prev 13:1604-1609
29. Welters CF, Dejong CH, Deutz NE, Heineman E (1999) Effects of parenteral arginine supplementation on the intestinal adaptive response after massive small bowel resection in the rat. J Surg Res 85:259-266
30. Osowska S, Moinard C, Neveux N, Loi C, Cynober L (2004) Citrulline increases arginine pools and restores nitrogen balance after massive intestinal resection. Gut 53:1781-1786
31. Palmer JP, Benson JW, Walter RM, Ensinck JW (1976) Arginine-stimulated acute phase of insulin and glucagon secretion in diabetic subjects. J Clin Invest 58:565-570
32. Calbet JA, MacLean DA (2002) Plasma glucagon and insulin responses depend on the rate of appearance of amino acids after ingestion of different protein solutions in humans. J Nutr 132:2174-2182
33. Paddon-Jones D, Sheffield-Moore M, Zhang XJ, Volpi E, Wolf SE, Aarsland A, Ferrando AA, Wolfe RR (2004) Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am J Physiol Endocrinol Metab 286:E321-E328