Evaluation of the stimulant content of dietary supplements marketed as "Ephedra-Free"

Journal of Herbal Pharmacotherapy

Volumn 7, Issue 1, 2007, Pages 65-72

  Gregory, Philip J ^a  

^a CREIGHTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Dietary supplements; Ephedra; Ephedra free; Stimulants; Survey

Indexed keywords

CAFFEINE; CENTRAL STIMULANT AGENT; EPHEDRA EXTRACT; METHYLXANTHINE; OXEDRINE; THEOBROMINE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; DATA BASE; DIET SUPPLEMENTATION; HEALTH HAZARD; INFORMATION RETRIEVAL; INTERNET; MARKETING; PATIENT COUNSELING; PRIORITY JOURNAL;

ALKALOIDS; ANTI-OBESITY AGENTS; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; DIETARY SUPPLEMENTS; DRUG AND NARCOTIC CONTROL; DRUG LABELING; DRUGS, CHINESE HERBAL; EPHEDRINE; HUMANS; MASS SPECTROMETRY; METALS, HEAVY; PHYTOTHERAPY; PLANT PREPARATIONS;

EID: 34347402233     PISSN: 15228940     EISSN: 15229106     Source Type: Journal    
DOI: 10.1300/J157v07n01_06     Document Type: Article

References (14)

1. Jarvis L. Dietary supplements stay healthy in 2002-Consumer specialties. Chemical Market Reporter, Sept 8, 2003.
2. Tyler VE. The Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed. Pharmaceutical Products Press: New York, 1993.
3. Haller CA, Jacob P III, Benowitz NL. Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use. Clin Pharmacol Ther 2002;71: 421-32.
4. Shekelle PG, Hardy ML, Morton SC, et al. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: A meta-analysis. JAMA 2003;289: 1537-45.
5. Jellin JM, Gregory PJ, Batz F, et al. Natural medicines comprehensive database. Therapeutic Research Faculty: Stockton, CA, 2004. Available from: www.naturaldatabase.com. Accessed July 28, 2004.
6. Samenuk D, Link MS, Homoud MK, et al. Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine. Mayo Clin Proc 2002;77:12-6.
7. Morgenstern LB, Viscoli CM, Kernan WN, et al. Use of ephedra-containing products and risk for hemorrhagic stroke. Neurology 2003;60:132-5.
8. Pittler MH, Ernst E. Dietary supplements for body-weight reduction: A systematic review. Am J Chn Nutr 2004;79:529-36.
9. Gregory PJ. Natural medicines in the clinical management of obesity. Natural Medicines Comprehensive Database 2004. Available from: www.naturaldatabase.com. Accessed July 29, 2004.
10. Fugh-Berman A, Myers A. Citrus aurantium, an ingredient of dietary supplements marketed for weight loss: Current status of clinical and basic Research. Exp Biol Med 2004;229:698-704.
11. Calapai G, Firenzuoli F, Saitta A, et al. Antiobesity and cardiovascular toxic effects of Citrus aurantium extracts in the rat: A preliminary report. Fitoterapia 1999;70:586-92.
12. Huang YT, Wang GF, Chen CF, et al. Fructus aurantii reduced portal pressure in portal hypertensive rats. Life Sci 1995;57:2011-20.
13. Nykamp DL, Fackih MN, Compton AL. Possible association of acute lateral-wall myocardial infarction and bitter orange supplement. Ann Pharmacother 2004;38:812-6.
14. Meadows M. Ensuring the safety of dietary supplements. FDA Consumer Magazine 2004; July-August. Available from: http://www.fda.gov/fdac/ features/2OO4/404_supp.html. Accessed July 29, 2004.