Measuring International Normalized Ratios in Long-Term Care: A Comparison of Commercial Laboratory and Point-of-Care Device Results

Journal of the American Medical Directors Association

Volumn 8, Issue 6, 2007, Pages 404-408

  Bluestein, Daniel ^a   Brantley, Cynthia ^d   Barnes Eley, Myra ^b   Gravenstein, Stefan ^a   Basta, Sameh ^c  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b CENTER FOR PEDIATRIC RESEARCH   (United States)

^c Sentara Health Systems   (United States)

^d NONE

Author keywords

anticoagulation; long term care; Point of care systems; warfarin

Indexed keywords

WARFARIN;

ACCURACY; AGED; ARTICLE; CASE STUDY; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMOGRAPHY; FEMALE; HEART ATRIUM FIBRILLATION; HUMAN; INFORMATION PROCESSING; INTERMETHOD COMPARISON; INTERNATIONAL NORMALIZED RATIO; LONG TERM CARE; MALE; NURSING HOME PATIENT; POINT OF CARE TESTING; RELIABILITY; RESIDENTIAL CARE; UNITED STATES; VEIN PUNCTURE; VENOUS THROMBOEMBOLISM;

EID: 34347401395     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2007.02.006     Document Type: Article

References (20)

1. Latif A.K., Peng X., and Messinger-Rapport B.J. Predictors of anticoagulation prescription in nursing home residents with atrial fibrillation. J Am Med Dir Assoc 6 (2005) 128-131
2. Weinberg A.D., Altman J.S., and Pals J.K. Quality improvement case study: Warfarin sodium interactions. J Am Med Dir Assoc 7 (2006) 315-318
3. Ansell J., Hirsh J., Poller L., Bussey H., Jacobson A., and Hylek E. The pharmacology and management of the vitamin K antagonists: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126 3 Suppl (2004) 204S-233S
4. Sunderji R., Gin K., Shalansky K., et al. Clinical impact of point-of-care vs laboratory measurement of anticoagulation. Am J Clin Pathol 123 2 (2005) 184-188
5. Dorfman D.M., Goonan E.M., Boutilier M.K., Jarolim P., Tanasijevica M., and Goldhaber S.Z. Point-of-care (POC) versus central laboratory instrumentation for monitoring oral anticoagulation. Vasc Med 10 1 (2005) 23-27
6. McBane II R.D., Felty C.L., Hartgers M.L., Chaudhry R., Beyer L.K., and Santrach P.J. Importance of device evaluation for point-of-care prothrombin time international normalized ratio testing programs. Mayo Clin Proc 80 2 (2005) 181-186
7. Poller L., Keown M., Chauhan N., et al. Reliability of international normalised ratios from two point of care test systems: Comparison with conventional methods. BMJ 327 7405 (2003) 30
8. Finck K.M., Doetkott C., and Miller D.R. Clinical impact of interlaboratory variation in international normalized ratio determinations. Am J Health Syst Pharm 58 8 (2001) 684-688
9. Hobbs F.D., Fitzmaurice D.A., Murray E.T., Holder R., Rose P.E., and Roper J.L. Is the international normalised ratio (INR) reliable?. A trial of comparative measurements in hospital laboratory and primary care settings. J Clin Pathol 52 7 (1999) 494-497
10. Reed C., and Rickman H. Accuracy of International Normalized Ratio determined by portable whole-blood coagulation monitor versus a central laboratory. Am J Health Syst Pharm 56 16 (1999) 1619-1623
11. Reiss R.A., Haas C.E., Griffis D.L., Porter B., and Tara M.A. Point-of-care versus laboratory monitoring of patients receiving different anticoagulant therapies. Pharmacotherapy 22 6 (2002) 677-685
12. Jonsson M., Hillarp A., and Svensson P. Comparison between CoaguChek S- and Owren-type prothrombin time assay for monitoring anticoagulant therapy. Thromb Res 114 2 (2004) 83-89
13. Eldor A., and Schwartz J. Self-management of oral anticoagulants with a whole blood prothrombin-time monitor in elderly patients with atrial fibrillation. Pathophysiol Haemost Thromb 32 3 (2002) 99-106
14. Chapman D.C., Stephens M.A., Hamann G.L., Bailey L.E., and Dorko C.S. Accuracy, clinical correlation, and patient acceptance of two handheld prothrombin time monitoring devices in the ambulatory setting. Ann Pharmacother 33 7-8 (1999) 775-780
15. INRatio meter [product information] (2003), HemoSense, Inc, San Jose, CA
16. Horton J.D., and Bushwick B.M. Warfarin therapy: evolving strategies in anticoagulation. Am Fam Physician 59 3 (1999) 635-646
17. Crowther M.A., Douketis J.D., Schnurr T., et al. Oral vitamin K lowers the international normalized ratio more rapidly than subcutaneous vitamin K in the treatment of warfarin-associated coagulopathy: A randomized, controlled trial. Ann Intern Med 137 (2002) 251-254
18. Perry S.L., Samsa G.P., and Ortel T.L. Point-of-care testing of the international normalized ratio in patients with antiphospholipid antibodies. Thromb Haemost 94 6 (2005) 1196-1202
19. Quien E.T., Morales E., Cisar L.A., et al. Plasma tissue factor antigen levels in capillary whole blood and venous blood: Effect of tissue factor on prothrombin time. Am J Hematol 55 4 (1997) 193-198
20. Kitchen S. Problems in laboratory monitoring of heparin dosage. Br J Haematol 111 2 (2000) 397-406