The profile of antioxidant systems and lipid peroxidation across the crypt-villus axis in rat intestine

Digestive Diseases and Sciences

Volumn 52, Issue 8, 2007, Pages 1840-1844

  Turan, Aasma ^a   Mahmood, Akhtar ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Catalase; Crypt villus axis; Glutathione reductase; Glutathione S transferase; Intestinal epithelial cells; Superoxide dismutase

Indexed keywords

ARACHIS OIL; COCONUT OIL; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LIPID; MALONALDEHYDE; SUNFLOWER OIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME BLOOD LEVEL; ENZYME RELEASE; INTESTINE ABSORPTION; INTESTINE CRYPT; INTESTINE VILLUS; LIPID PEROXIDATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; RAT;

ANIMALS; CATALASE; DIETARY FATS; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; INTESTINAL MUCOSA; INTESTINE, SMALL; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 34347397584     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-9633-z     Document Type: Article

References (22)

1. Johnson IT (2002) Anticarcinogenic effects of diet-related apoptosis in the colorectal mucosa. Food Chem Toxicol 40:1171-1178
2. Troyer D, Fernandes G (1996) Nutrition and apoptosis. SO Nutr Res 16:1959-1987
3. Avual CPR, Lawrence RA, Jolly CA, Fernandes G (2000) Role of n-3 polyunsaturated fatty acids (PUFA) in autoimmunity, inflammation, carcinogenesis, and apoptosis. Rec Res Dev Lipids 4:303-319
4. Kruidenier L, Kuiper I, Lamers CB, Verspaget HW (2003) Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants. J Pathol 201:28-36
5. Wahnon R, Cogan U, Mokady S (1992) Dietary fish oil modulates the alkaline phosphatase activity and not the fluidity of rat intestinal microvillus membrane. J Nutr 122:1077-1084
6. Cornell JS, Meister A (1976) Glutathione and gamma glutamyl cycle enzymes in crypt-villus tip cells of rat jejunal mucosa. Proc Natl Acad Sci USA 73:420-422
7. Weiser MM (1973) Intestinal epithelial cells surface membrane glycoprotein synthesis. J Biol Chem 215:2536-2541
8. Bergmeyer MVC (1963) Methods of enzymatic analysis. Academic Press, New York, pp 783-785
9. Dahlqvist A (1964) Method for the assay of intestinal disaccharidases. Anal Biochem 7:18-25
10. Horn HD (1971) Methods of enzymatic analysis. Academic Press, New York, pp 875-881
11. Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione-S-transferases: the first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-7139
12. Kono Y (1978) Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys 186:189-195
13. Luck H (1971) Methods of enzymatic analysis. Academic Press, New York, pp 885-888
14. Beuge JA, Aust SD (1978) Microsomal lipid peroxidation. Methods Enzymol 52:302-310
15. Dudeja PK, Brasitus TA (1993) Inactivation of rat small intestinal brush-border membrane alkaline phosphatase by oxygen free radicals. Gastroenterology 105:357-366
16. Lowry OH, Rosenbrough NS, Farr AL, Randall RL (1951) Protein measurement with folin phenol reagent. J Biol Chem 193:265-275
17. Brasitus TA, Dudeja PK (1985) Regional differences in the lipid composition and fluidity of rat colonic brush-border membranes. Biochim Biophys Acta 819:10-17
18. Cheng J, Sharma R, Yang Y, Singhal SS, Sharma A, Saini MK, Singh SV, Zimniak P, Awasthi S, Awasthi YC (2001) Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress. J Biol Chem 276:41213-41223
19. Basivireddy J, Vasudevan A, Jacob M, Balasubramanian KA (2002) Indomethacin-induced mitochondrial dysfunction and oxidative stress in villus enterocytes. Biochem Pharmacol 64:339-349
20. Kim H, Choi S, Lee HJ, Choi H (2003) Suppression of FA synthase by dietary polyunsaturated fatty acids is mediated by fat itself, not by peroxidative mechanism. J Biochem Mol Biol 36:258-264
21. Avula CP, Fernandes G (1999) Modulation of antioxidant enzymes and apoptosis in mice by dietary lipids and treadmill exercise. J Clin Immunol 19:35-44
22. Tahir MK, Ozer N, Mannervik B (1988) Isoenzymes of glutathione transferase in rat small intestine. Biochem J 253:759-764