Cyclic AMP dependent down regulation in the relaxation of smooth muscle cells of cat esophagitis

Archives of Pharmacal Research

Volumn 30, Issue 6, 2007, Pages 715-722

  Chang, Yell Shin ^a   Yul, Pyo Lee ^a   Hyun, Ju Song ^a   Hyun, Dong Je ^b   Uy, Dong Sohn ^a  

^a Chung Ang University   (South Korea)

^b Catholic University of Daegu   (South Korea)

Author keywords

Adenylyl cyclase; cAMP; Esophagitis; Relaxation; VIP

Indexed keywords

EID: 34347395970     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02977633     Document Type: Article

References (37)

1. Behar, J., Guenard, V., Walsh, J. H., and Biancani, P., VIP and acetylcholine: neurotransmitters in esophageal circular smooth muscle. Am. J. Physiol., 257, G380-385 (1989).
2. Bell, N. J., Burget, D., Howden, C. W., Wilkinson, J., and Hunt, R. H., Appropriate acid suppression for the management of gastro-oesophageal reflux disease. Digestion, 51, 59-67 (1992).
3. Biancani, P., Sohn, U. D., Rich, H. G., Harnett, K. M., and Behar, J., Signal transduction pathways in esophageal and lower esophageal sphincter circular muscle. Am. J. Med., 103, 23S-28S (1997).
4. Biancani, P., Walsh, J. H., and Behar, J., Vasoactive intestinal polypeptide. A neurotransmitter for lower esophageal sphincter relaxation. J. Clin. Invest., 73, 963-967 (1984).
5. Bitar, K. N. and Makhlouf, G. M., Receptors on smooth muscle cells: characterization by contraction and specific antagonists. Am. J. Physiol., 242, G400-407 (1982a).
6. Bitar, K. N. and Makhlouf, G. M., Relaxation of isolated gastric smooth muscle cells by vasoactive intestinal peptide. Science, 216, 531-533 (1982b).
7. 2+ entry regulates Ca(2+)-inhibitable adenylyl cyclase in non-excitable cells. J. Biol. Chem., 270, 1149-1155 (1995).
8. Choi, E. J., Wong, S. T., Hinds, T. R., and Storm, D. R., Calcium and muscarinic agonist stimulation of type I adenylylcyclase in whole cells. J. Biol. Chem., 267, 12440-12442 (1992a).
9. Choi, E. J., Xia, Z., and Storm, D. R., Stimulation of the type III olfactory adenylyl cyclase by calcium and calmodulin. Biochemistry, 31, 6492-6498 (1992b).
10. Cooper, D. M., Mons, N., and Karpen, J. W., Adenylyl cyclases and the interaction between calcium and cAMP signalling. Nature, 374, 421-424 (1995).
11. Diamant, N. E. and El-Sharkawy, T. Y., Neural control of esophageal peristalsis. A conceptual analysis. Gastroenterology, 72, 546-556 (1977).
12. Eastwood, G. L., Castell, D. O., and Higgs, R. H., Experimental esophagitis in cats impairs lower esophageal sphincter pressure. Gastroenterology, 69, 146-153 (1975).
13. Fabiato, A. and Fabiato, F., Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. J. Physiol., 75, 463-505 (1979).
14. Federman, A. D., Conklin, B. R., Schrader, K. A., Reed, R. R., and Bourne, H. R., Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits. Nature, 356, 159-161 (1992).
15. Goyal, R. K., Rattan, S., and Said, S. I., VIP as a possible neurotransmitter of non-cholinergic non-adrenergic inhibitory neurones. Nature, 288, 378-380 (1980).
16. Grider, J. R., Cable, M. B., Said, S. I., and Makhlouf, G. M., Vasoactive intestinal peptide as a neural mediator of gastric relaxation. Am. J. Physiol., 248, G73-78 (1985b).
17. Harnett, K. M., Cao, W., Kim, N., Sohn, U. D., Rich, H., Behar, J., and Biancani, P., Signal transduction in esophageal and LES circular muscle contraction. Yale. J. Biol. Med., 72, 153-168 (1999).
18. Iwami, G., Kawabe, J., Ebina, T., Cannon, P. J., Homcy, C. J., and Ishikawa, Y., Regulation of adenylyl cyclase by protein kinase A. J. Biol. Chem., 270, 12481-12484 (1995).
19. Iyengar, R., Molecular and functional diversity of mammalian Gs-stimulated adenylyl cyclases. Faseb. J., 7, 768-775 (1993).
20. Kim, N., Sohn, U. D., Mangannan, V., Rich, H., Jain, M. K., Behar, J., and Biancani, P., Leukotrienes in acetylcholine-induced contraction of esophageal circular smooth muscle in experimental esophagitis. Gastroenterology, 112, 1548-1558 (1997).
21. Makhlouf, G. M. and Murthy, K. S., Signal transduction in gastrointestinal smooth muscle. Cell Signal., 9, 269-276 (1997).
22. Murthy, K. S., Grider, J. R., Jin, J. G., and Makhlouf, G. M., Interplay of VIP and nitric oxide in the regulation of neuromuscular activity in the gut. Arch. Int. Pharmacodyn. Ther., 329, 27-38 (1995).
23. Murthy, K. S., Grider, J. R., Jin, J. G., and Makhlouf, G. M., Interplay of VIP and nitric oxide in the regulation of neuromuscular function in the gut. Ann. N. Y. Acad. Sci., 805, 355-62; discussion 362-3 (1996b).
24. Premont, R. T., Jacobowitz, O., and Iyengar, R., Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3́,5́-monophosphate-dependent phosphorylation. Endocrinology, 131, 2774-2784 (1992).
25. Rekik, M., Delvaux, M., Tack, I., Frexinos, J., and Bueno, L., VIP-induced relaxation of guinea-pig intestinal smooth muscle cells: sequential involvement of cyclic AMP and nitric oxide. Br. J. Pharmacol., 118, 477-484 (1996).
26. Sanders, K. M., G protein-coupled receptors in gastrointestinal physiology. IV. Neural regulation of gastrointestinal smooth muscle. Am. J. Physiol., 275, G1-7 (1998).
27. Shin, C. Y., La, H. O., Lee, Y. P., Lee, D. W., Kim, D. S., Huh, I. H., and Sohn, U. D., The alteration of intracellular signaling on the smooth muscle cells contraction in cat esophagitis. Life Science, 74, 2199-2211 (2004).
28. Sohn, U. D., Chiu, T. T., Bitar, K. N., Hillemeier, C., Behar, J., and Biancani, P., Calcium requirements for acetylcholine-induced contraction of cat esophageal circular muscle cells. Am. J. Physiol., 266, G330-338 (1994).
29. Sohn, U. D., Han, B., Tashjian, A. H. Jr., Behar, J., and Biancani, P., Agonist-independent, muscle-type-specific signal transduction pathways in cat esophageal and lower esophageal sphincter circular smooth muscle. J. Pharmacol. Exp. Ther., 273, 482-491 (1995).
30. Sohn, U. D., Harnett, K. M., Cao, W., Rich, H., Kim, N., Behar, J., and Biancani, P., Acute experimental esophagitis activates a second signal transduction pathway in cat smooth muscle from the lower esophageal sphincter. J. Pharmacol. Exp. Ther., 283, 1293-1304 (1997).
31. Sohn, U. D., Harnett, K. M., De Petris, G., Behar, J., and Biancani, P., Distinct muscarinic receptors, G proteins and phospholipases in esophageal and lower esophageal sphincter circular muscle. J. Pharmacol. Exp. Ther., 267, 1205-1214 (1993).
32. Sunahara, R. K., Dessauer, C. W., and Gilman, A. G., Complexity and diversity of mammalian adenylyl cyclases. Annu. Rev. Pharmacol. Toxicol., 36, 461-480 (1996).
33. Tang, W. J. and Gilman, A. G., Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits. Science, 254, 1500-1503 (1991).
34. Taussig, R. and Gilman, A. G., Mammalian membrane-bound adenylyl cyclases. J. Biol. Chem., 270, 1-4 (1995).
35. Taussig, R., Iniguez-Lluhi, J. A., and Gilman, A. G., Inhibition of adenylyl cyclase by Gi alpha. Science, 261, 218-221 (1993a).
36. Taussig, R., Quarmby, L. M., and Gilman, A. G., Regulation of purified type I and type II adenylylcyclases by G protein beta gamma subunits. J. Biol. Chem., 268, 9-12 (1993b).
37. Taussig, R., Tang, W. J., Hepler, J. R., and Gilman, A. G., Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases. J. Biol. Chem., 269, 6093-6100 (1994).