Semi-automated imaging system to quantitate estrogen and progesterone receptor immunoreactivity in human breast cancer

Journal of Microscopy

Volumn 226, Issue 3, 2007, Pages 244-255

  Sharangpani, G M ^a   Joshi, A S ^a   Porter, K ^b   Deshpande, A S ^a   Keyhani, S ^c   Naik, G A ^a   Gholap, A S ^a   Barsky, S H ^c  

^a BioImagene Inc ^*  (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Image algorithms; Image intensity; Nuclear immunoreactivity; Semi automation

Indexed keywords

AUTOMATION; COLOR; COLORIMETRY; DISEASES; IMAGE ACQUISITION; IMAGE ANALYSIS; IMAGE ENHANCEMENT; IMAGING SYSTEMS; LUMINANCE; MEDICAL IMAGING; PATTERN RECOGNITION;

ESTROGEN RECEPTOR; HUMAN BREAST CANCER; IMAGE ALGORITHMS; IMAGE INTENSITIES; IMMUNOREACTIVITIES; INTEROBSERVER VARIABILITY; INTRA-OBSERVER VARIABILITY; NUCLEAR IMMUNOREACTIVITY; PROGESTERONE RECEPTOR; SEMI-AUTOMATION;

PIXELS;

ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

ARTICLE; BREAST CANCER; COLORIMETRY; CORRELATION ANALYSIS; HUMAN; IMAGE ANALYSIS; IMAGE ENHANCEMENT; IMAGE PROCESSING; IMAGE QUALITY; IMAGING SYSTEM; IMMUNOREACTIVITY; MICROSCOPE; OBSERVER VARIATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

EID: 34347394158     PISSN: 00222720     EISSN: 13652818     Source Type: Journal    
DOI: 10.1111/j.1365-2818.2007.01772.x     Document Type: Article

References (18)

1. Adams, G.P., Tai, M.S., McCartney, J.E., Marks, J.D., Stafford, W.F. 3rd., Houston, L.L., Huston, J.S. & Weiner, L.M. (2006) Avidity-mediated enhancement of in vivo tumor targeting by single-chain Fv dimers. Clin. Cancer Res. 12, 1599 1605.
2. Allred, D.C., Harvey, J.M., Berardo, M. & Clark, G.M. (1998) Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod. Pathol. 11, 155 168.
3. Castelli, F., Frith, C., Frith, U. & Frith, C. (2000) Movement and mind: A functional imaging study of perception and interpretation of complex intentional movement patterns. NeuroImage 12, 314 325.
4. Chen, J.H. & Chuang, K.H. (2001) Image-based physiological artifacts estimation and correction technique for functional MRI. Magnet. Reson. Med. 46, 344 353.
5. Ellis, B., Decker, W.J. & McLaren, G. (2003) Histological reconstruction and automated image analysis. ChromaVision Medical Systems, Inc. US Patent 6, 631,203.
6. Ellis, B., Decker, W.J. & McLaren, G. (2005) Histological reconstruction and automated image analysis. Clarient, Inc. US Patent 6, 947,583.
7. Goldhirsch, A., Glick, J.H., Gelber, R.D., Coates, A.S. & Senn, H.J. (2001) Seventh international conference on adjuvant therapy of primary breast cancer. J. Clin. Oncol. 19, 3817 3827.
8. Gonzalez, R.C. & Woods, R.E. (1992) Digital Image Processing, pp. 174. Addison-Wesley, Boston.
9. Harvey, J.M., Clark, G.M., Osborne, C.K., & Allred, D.C. (1999) Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J. Clin. Oncol. 17, 1474 1481.
10. Jain, A.K. (1989) Fundamentals of Digital Image Processing, pp. 241 243. Prentice Hall, New Jersey.
11. Neves, J.I., Begnami, M.D., Arias, V. & Santos, G.C. (2005) Antigen retrieval methods and estrogen receptor immunoexpression using 1D5 antibody: a comparative study. Int. J. Surg. Pathol. 13, 353 357.
12. Osborne, C.K. (1998) Tamoxifen in the treatment of breast cancer. N. Engl. J. Med. 339, 1609 1618.
13. Pal, S.K. & Ghosh, A. (1992) Image segmentation using fuzzy correlation. Inf. Sci. 62, 223 250.
14. Pisano, E.D., Gatsonis, C., Hendrick, E. et al. The Digital Mammographic Imaging Screening Trial (DMIST) Investigators Group 2005) Diagnostic performance of digital versus film mammography for breast-cancer screening. New Eng. J. Med. 353, 1773 1783.
15. Ravdin, P.M., Green, S., Dorr, T.M. et al 1992) Prognostic significance of progesterone receptor levels in estrogen receptor-positive patients with metastatic breast cancer treated with tamoxifen: results of a prospective Southwest oncology group study. J. Clin. Oncol. 10, 1284 1291.
16. Reiner, B.I., Siegel, E.L., Flagle, C., Hooper, F.J., Cox, R.E. & Scanlon, M. (2000) Effect of film less imaging on the utilization of radiologic services. Radiology 215, 163 167.
17. Shao, Z.M., Li, J., Wu, J., Han, Q.X., Shen, Z.Z., Fontana, J.A., & Barsky, S.H. (1999) Neo-adjuvant chemotherapy for operable breast cancer induces apoptosis. Breast Can. Res. Treat. 53, 263 269.
18. Wu, J., Shen, Z.Z., Lu, J.S., Jiang, M., Han, Q.X., Fontana, J.A., Barsky, S.H. & Shao, Z.M. (1999) Prognostic role of p27 and apoptosis in human breast cancer. Br. J. Cancer 79, 1572 1578.