Differentially expressed gene networks in cultured smooth muscle cells from normal and neuropathic bladder

Journal of Smooth Muscle Research

Volumn 43, Issue 2, 2007, Pages 55-72

  Dozmorov, Mikhail G ^a   Kropp, Bradley P ^a   Hurst, Robert E ^a   Cheng, Earl Y ^a,b   Lin, Hsueh Kung ^a,c  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b CHILDREN'S MEMORIAL HOSPITAL   (United States)

^c University of Oklahoma Medical Center   (United States)

Author keywords

Array analysis; Gene expression; Neuropathic bladder; Smooth muscle cells

Indexed keywords

ARTICLE; BLADDER; CELL CULTURE; COMPARATIVE STUDY; DNA MICROARRAY; GENE EXPRESSION PROFILING; HUMAN; INNERVATION; METABOLISM; NEUROGENIC BLADDER; PATHOLOGY; PATHOPHYSIOLOGY; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER;

CELLS, CULTURED; GENE EXPRESSION PROFILING; HUMANS; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; URINARY BLADDER; URINARY BLADDER, NEUROGENIC;

EID: 34347379515     PISSN: 09168737     EISSN: None     Source Type: Journal    
DOI: 10.1540/jsmr.43.55     Document Type: Article

References (37)

1. Adam, R.M., Eaton, S.H., Estrada, C., Nimgaonkar, A., Shih, S.C., Smith, L.E., Kohane, I.S., Bagli, D. and Freeman, M.R. (2004). Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells. Physiol. Genomics 20: 36-44.
2. Ahmed, S. and Carney, A. (1981). Urinary undiversion in myelomeningocele patients with an ileal conduit diversion. J. Urol. 125: 847-852.
3. Albrecht, M., Janssen, M., Konrad, L., Renneberg, H. and Aumuller, G. (2002). Effects of dexamethasone on proliferation of and fibronectin synthesis by human primary prostatic stromal cells in vitro. Andrologia 34: 11-21.
4. Beqaj, S.H., Donovan, J.L., Liu, D.B., Harrington, D.A., Alpert, S.A. and Cheng, E.Y. (2005). Role of basic fibroblast growth factor in the neuropathic bladder phenotype. J. Urol. 174: 1699-1703.
5. Berrou, E. and Bryckaert, M. (2001). Platelet-derived growth factor inhibits smooth muscle cell adhesion to fibronectin by ERK-dependent and ERK-independent pathways. J. Biol. Chem. 276: 39303-39309.
6. Carreras, I., Rich, C.B., Panchenko, M.P. and Foster, J.A. (2002). Basic fibroblast growth factor decreases elastin gene transcription in aortic smooth muscle cells. J. Cell Biochem. 85: 592-600.
7. Chang, F., Lee, J.T., Navolanic, P.M., Steelman, L.S., Shelton, J.G., Blalock, W.L., Franklin, R.A. and McCubrey, J.A. (2003). Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 17: 590-603.
8. Deveaud, C.M., Macarak, E.J., Kucich, U., Ewalt, D.H., Abrams, W.R. and Howard, P.S. (1998). Molecular analysis of collagens in bladder fibrosis. J. Urol. 160: 1518-1527.
9. Eisen, M.B., Spellman, P.T., Brown, P.O. and Botstein, D. (1998). Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95: 14863-14868.
10. Fernandes, D.J., Bonacci, J.V. and Stewart, A.G. (2006). Extracellular matrix, integrins, and mesenchymal cell function in the airways. Curr. Drug Targets 7: 567-577.
11. Garl, P.J., Wenzlau, J.M., Walker, H.A., Whitelock, J.M., Costell, M. and Weiser-Evans, M.C. (2004). Perlecan-induced suppression of smooth muscle cell proliferation is mediated through increased activity of the tumor suppressor PTEN. Circ. Res. 94: 175-183.
12. Giancotti, F.G. and Ruoslahti, E. (1999). Integrin signaling. Science 285: 1028-1032.
13. Grothe, C., Haastert, K. and Jungnickel, J. (2006). Physiological function and putative therapeutic impact of the FGF-2 system in peripheral nerve regeneration-Lessons from in vivo studies in mice and rats. Brain Res. Brain. Res. Rev. 51: 293-299.
14. Gu, J., Tamura, M. and Yamada, K.M. (1998). Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways. J. Cell Biol. 143: 1375-1383.
15. Haier, J. and Nicolson, G.L. (2002). PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow. Oncogene 21: 1450-1460.
16. κB. J. Biol. Chem. 275: 883-889.
17. h/transglutaminase 2 inhibits cell migration through interaction with cytoplasmic tail of integrin a subunits. J. Biol. Chem. 279: 36593-36600.
18. Kawai, Y., Hayashi, T., Eguchi, K., Asazuma, K., Masamura, K., Iwamuro, A., Takano, Y., Tada, H., Matsukawa, S. and Miyamori, I. (1998). Effects of brief glucocorticoid exposure on growth of vascular smooth muscle cells in culture. Biochem. Biophys. Res. Commun. 245: 493-496.
19. Keshtgar, A.S. and Rickwood, A.M. (1998). Urological consequences of incomplete cord lesions in patients with myelomeningocele. Br. J. Urol. 82: 258-260.
20. Li, L., Liu, F. and Ross, A.H. (2003). PTEN regulation of neural development and CNS stem cells. J. Cell Biochem. 88: 24-28.
21. Lin, H.K., Cowan, R., Moore, P., Zhang, Y., Yang, Q., Peterson, J.A.Jr., Tomasek, J.J., Kropp, B.P. and Cheng, E.Y. (2004). Characterization of neuropathic bladder smooth muscle cells: Implications for tissue engineering. J. Urol. 171: 1348-1352.
22. Lindner, V. and Reidy, M.A. (1991). Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Proc. Natl. Acad. Sci. USA 88: 3739-3743.
23. Ling, Y., Maile, L.A., Badley-Clarke, J. and Clemmons, D.R. (2005). DOK1 mediates SHP-2 binding to the alpha V beta 3 integrin and thereby regulates insulin-like growth factor I signaling in cultured vascular smooth muscle cells. J. Biol. Chem. 280: 3151-3158.
24. Mendizabal, S., Estornell, F., Zamora, I., Sabater, A., Ibarra, F.G. and Simon, J. (2005). Renal transplantation in children with severe bladder dysfunction. J. Urol. 173: 226-229.
25. Mingin, G.C., Nguyen, H.T., Mathias, R.S., Shepherd, J.A., Glidden, D. and Baskin, L.S. (2002). Growth and metabolic consequences of bladder augmentation in children with myelomeningocele and bladder exstrophy. Pediatrics 110: 1193-1198.
26. Nguyen, T.T., Ward, J.P. and Hirst, S.J. (2005). β1-Integrins mediate enhancement of airway smooth muscle proliferation by collagen and fibronectin. Am. J. Respir. Crit. Care Med. 171: 217-223.
27. Nunlist, E.H., Dozmorov, I., Tang, Y., Cowan, R., Centola, M. and Lin, H.K. (2004). Partitioning of 5a-dihydrotestosterone and 5a-androstane-3a, 17b-diol activated pathways for stimulating human prostate cancer LNCaP cell proliferation. J. Steroid. Biochem. Mol. Biol. 91: 157-170.
28. Park, M.J., Kim, M.S., Park, I.C., Kang, H.S., Yoo, H., Park, S.H., Rhee, C.H., Hong, S.I. and Lee, S.H. (2002). PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation. Cancer Res. 62: 6318-6322.
29. Qiu, H., Kordunskaya, S. and Yantiss, R.K. (2003). Transitional cell carcinoma arising in the gastric remnant following gastrocystoplasty: a case report and review of the literature. Int. J. Surg. Pathol. 11: 143-147.
30. Sawhney, R.S., Cookson, M.M., Omar, Y., Hauser, J. and Brattain, M.G. (2006). Integrin a2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway. J. Biol. Chem. 281: 8497-8510.
31. Tamura, M., Gu, J., Takino, T. and Yamada, K.M. (1999). Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas. Cancer Res. 59: 442-449.
32. Thomas, G., Clayton, A., Thomas, J., Davies, M. and Steadman, R. (2003). Structural and functional changes in heparan sulfate proteoglycan expression associated with the myofibroblastic phenotype. Am. J. Pathol. 162: 977-989.
33. Vadigepalli, R., Chakravarthula, P., Zak, D.E., Schwaber, J.S. and Gonye, G.E. (2003). PAINT: a promoter analysis and interaction network generation tool for gene regulatory network identification. OMICS 7: 235-252.
34. van Gool, J.D., Dik, P. and de Jong, T.P. (2001). Bladder-sphincter dysfunction in myelomeningocele. Eur. J. Pediatr. 160: 414-420.
35. Wessely, R., Hengst, L., Jaschke, B., Wegener, F., Richter, T., Lupetti, R., Paschalidis, M., Schomig, A., Brandl, R. and Neumann F.J. (2003). A central role of interferon regulatory factor-1 for the limitation of neointimal hyperplasia. Hum. Mol. Genet. 12: 177-187.
36. Wright, G.W. and Simon, R.M. (2003). A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics 19: 2448-2455.
37. Wu, X., Senechal, K., Neshat, M.S., Whang, Y.E. and Sawyers, C.L. (1998). The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc. Natl. Acad. Sci. USA 95: 15587-15591.