The relationships between plasma potassium, muscle excitability and fatigue during voluntary exercise in humans

Experimental Physiology

Volumn 92, Issue 4, 2007, Pages 705-715

  Shushakov, Vladimir ^a   Stubbe, Christian ^a   Peuckert, Antje ^a   Endeward, Volker ^a   Maassen, Norbert ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM;

ADULT; ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAM; EXERCISE; HAND GRIP; HUMAN; MALE; MUSCLE ACTION POTENTIAL; MUSCLE EXCITATION; MUSCLE FATIGUE; MUSCLE FUNCTION; NORMAL HUMAN; POTASSIUM BLOOD LEVEL; SARCOLEMMA; WORKLOAD;

EID: 34347378661     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2006.036384     Document Type: Article

References (61)

1. Almers W, Stanfield PR & Stuhmer W (1983). Slow changes in currents through sodium channels in frog muscle membrane. J Physiol 339, 253 271.
2. Arendt-Nielsen L & Mills KR (1988). Muscle fibre conduction velocity, mean power frequency, mean EMG voltage and force during submaximal fatiguing contractions of human quadriceps. Eur J Appl Physiol Occup Physiol 58, 20 25.
3. Bangsbo J (1994). The physiology of soccer - with special reference to intense intermittent exercise. Acta Physiol Scand Suppl 619, 1 155.
4. Bellemare F & Garzaniti N (1988). Failure of neuromuscular propagation during human maximal voluntary contraction. J Appl Physiol 64, 1084 1093.
5. Bigland-Ritchie B, Johansson R, Lippold OC, Smith S & Woods JJ (1983a). Changes in motoneurone firing rates during sustained maximal voluntary contractions. J Physiol 340, 335 346.
6. Bigland-Ritchie B, Johansson R, Lippold OC & Woods JJ (1983b). Contractile speed and EMG changes during fatigue of sustained maximal voluntary contractions. J Neurophysiol 50, 313 324.
7. Bland JM & Altman DG (1995). Calculating correlation coefficients with repeated observations: Part 1 - Correlation within subjects. BMJ 310, 446.
8. Brody LR, Pollock MT, Roy SH, De Luca CJ & Celli B (1991). pH-induced effects on median frequency and conduction velocity of the myoelectric signal. J Appl Physiol 71, 1878 1885.
9. Cairns SP, Hing WA, Slack JR, Mills RG & Loiselle DS (1997). Different effects of raised [K+]o on membrane potential and contraction in mouse fast- and slow-twitch muscle. Am J Physiol Cell Physiol 273, C598 C611.
10. Clausen T, Overgaard K & Nielsen OB (2004). Evidence that the Na+-K+ leak/pump ratio contributes to the difference in endurance between fast- and slow-twitch muscles. Acta Physiol Scand 180, 209 216.
11. Cupido CM, Galea V & McComas AJ (1996). Potentiation and depression of the M wave in human biceps brachii. J Physiol 491, 541 550.
12. De Luca CJ (1984). Myoelectrical manifestations of localized muscular fatigue in humans. Crit Rev Biomed Eng 11, 251 279.
13. Eberstein A & Beattie B (1985). Simultaneous measurement of muscle conduction velocity and EMG power spectrum changes during fatigue. Muscle Nerve 8, 768 773.
14. Green S, Langberg H, Skovgaard D, Bulow J & Kjaer M (2000). Interstitial and arterial-venous [K+] in human calf muscle during dynamic exercise: effect of ischaemia and relation to muscle pain. J Physiol 529, 849 861.
15. Hagg GM (1992). Interpretation of EMG spectral alterations and alteration indexes at sustained contraction. J Appl Physiol 73, 1211 1217.
16. Hallen J (1996). K+ balance in humans during exercise. Acta Physiol Scand 156, 279 286.
17. Hallen J, Gullestad L & Sejersted OM (1994). K+ shifts of skeletal muscle during stepwise bicycle exercise with and without β-adrenoceptor blockade. J Physiol 477, 149 159.
18. Harrison AP & Flatman JA (1999). Measurement of force and both surface and deep M wave properties in isolated rat soleus muscles. Am J Physiol Regul Integr Comp Physiol 277, R1646 R1653.
19. Hicks A & McComas AJ (1989). Increased sodium pump activity following repetitive stimulation of rat soleus muscles. J Physiol 414, 337 349.
20. Hirche H, Schumacher E & Hagemann H (1980). Extracellular K+ concentration and K+ balance of the gastrocnemius muscle of the dog during exercise. Pflugers Arch 387, 231 237.
21. Holmberg E & Waldeck B (1980). On the possible role of potassium ions in the action of terbutaline on skeletal muscle contractions. Acta Pharmacol Toxicol (Copenh) 46, 141 149.
22. Jammes Y, Steinberg JG, Mambrini O, Bregeon F & Delliaux S (2005). Chronic fatigue syndrome: assessment of increased oxidative stress and altered muscle excitability in response to incremental exercise. J Intern Med 257, 299 310.
23. Juel C (1988). Muscle action potential propagation velocity changes during activity. Muscle Nerve 11, 714 719.
24. Juel C, Bangsbo J, Graham T & Saltin B (1990). Lactate and potassium fluxes from human skeletal muscle during and after intense, dynamic, knee extensor exercise. Acta Physiol Scand 140, 147 159.
25. Juel C, Pilegaard H, Nielsen JJ & Bangsbo J (2000). Interstitial K+ in human skeletal muscle during and after dynamic graded exercise determined by microdialysis. Am J Physiol Regul Integr Comp Physiol 278, R400 R406.
26. Kossler F, Lange F, Caffier G & Kuchler G (1989). Changes of the conduction velocity of isolated muscles induced by altered external potassium concentration. Biomed Biochim Acta 48, S465 S470.
27. Kranz H, Williams AM, Cassell J, Caddy DJ & Silberstein RB (1983). Factors determining the frequency content of the electromyogram. J Appl Physiol 55, 392 399.
28. Lieber RL, Jacobson MD, Fazeli BM, Abrams RA & Botte MJ (1992). Architecture of selected muscles of the arm and forearm: anatomy and implication for tendon transfer. J Hand Surg 17A, 787 798.
29. Lindinger MI & Sjogaard G (1991). Potassium regulation during exercise and recovery. Sports Med 11, 382 401.
30. Lindstrom L, Kadefors R & Petersen I (1977). An electromyographic index for localized muscle fatigue. J Appl Physiol 43, 750 754.
31. Lindstrom L, Magnusson R & Petersen I (1970). Muscular fatigue and action potential conduction velocity changes studied with frequency analysis of EMG signals. Electromyography 10, 341 356.
32. Maassen N (1996). Mechanism of fatigue in small muscle group. In The Physiology and Pathophysiology of Exercise Tolerance, ed. Steinacker JM & Ward SA, pp. 31 36. Plenum Press, New York.
33. McKenna MJ (1992). The roles of ionic processes in muscular fatigue during intense exercise. Sports Med 13, 134 145.
34. Macefield VG, Fuglevand AJ, Howell JN & Bigland-Ritchie B (2000). Discharge behaviour of single motor units during maximal voluntary contractions of a human toe extensor. J Physiol 528, 227 234.
35. Marsden CD, Meadows JC & Merton PA (1983). 'Muscular wisdom' that minimizes fatigue during prolonged effort in man: peak rates of motoneuron discharge and slowing of discharge during fatigue. Adv Neurol 39, 169 211.
36. Masuda K, Masuda T, Sadoyama T, Inaki M & Katsuta S (1999). Changes in surface EMG parameters during static and dynamic fatiguing contractions. J Electromyogr Kinesiol 9, 39 46.
37. Medbo JI & Sejersted OM (1990). Plasma potassium changes with high intensity exercise. J Physiol 421, 105 122.
38. Milner-Brown HS & Miller RG (1986). Muscle membrane excitation and impulse propagation velocity are reduced during muscle fatigue. Muscle Nerve 9, 367 374.
39. Mohr M, Nordsborg N, Nielsen JJ, Pedersen LD, Fischer C, Krustrup P & Bangsbo J (2004). Potassium kinetics in human muscle interstitium during repeated intense exercise in relation to fatigue. Pflugers Arch 448, 452 456.
40. Mortimer JT, Magnusson R & Petersen I (1970). Conduction velocity in ischemic muscle: effect on EMG frequency spectrum. Am J Physiol 219, 1324 1329.
41. Overgaard K, Nielsen OB, Flatman JA & Clausen T (1999). Relations between excitability and contractility in rat soleus muscle: role of the Na+-K+ pump and Na+/K+ gradients. J Physiol 518, 215 225.
42. Pedersen TH, Clausen T & Nielsen OB (2003). Loss of force induced by high extracellular [K+] in rat muscle: effect of temperature, lactic acid and β2-agonist. J Physiol 551, 277 286.
43. Pedersen TH, de Paoli F & Nielsen OB (2005). Increased excitability of acidified skeletal muscle: role of chloride conductance. J Gen Physiol 125, 237 246.
44. Pedersen PK, Kiens B & Saltin B (1999). Hyperoxia does not increase peak muscle oxygen uptake in small muscle group exercise. Acta Physiol Scand 166, 309 318.
45. Pedersen TH, Nielsen OB, Lamb GD & Stephenson DG (2004). Intracellular acidosis enhances the excitability of working muscle. Science 305, 1144 1147.
46. Peters EJ & Fuglevand AJ (1999). Cessation of human motor unit discharge during sustained maximal voluntary contraction. Neurosci Lett 274, 66 70.
47. Renaud JM & Light P (1992). Effects of K+ on the twitch and tetanic contraction in the sartorius muscle of the frog, Rana pipiens. Implication for fatigue in vivo. Can J Physiol Pharmacol 70, 1236 1246.
48. Ruff RL (1999). Effects of temperature on slow and fast inactivation of rat skeletal muscle Na+ channels. Am J Physiol Cell Physiol 277, C937 C947.
49. Ruff RL, Simoncini L & Stuhmer W (1988). Slow sodium channel inactivation in mammalian muscle: a possible role in regulating excitability. Muscle Nerve 11, 502 510.
50. Schneider G, Koch H, Maassen N & Leibfritz D (1994). 31P NMR spectroscopy of the human calf muscle during intensive interval exercise. Eur J Appl Physiol Occup Physiol 69, P14.
51. Sejersted OM & Sjogaard G (2000). Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise. Physiol Rev 80, 1411 1481.
52. Sjogaard G (1990). Exercise-induced muscle fatigue: the significance of potassium. Acta Physiol Scand Suppl 593, 1 63.
53. Stephens JA & Taylor A (1972). Fatigue of maintained voluntary muscle contraction in man. J Physiol 220, 1 18.
54. Stulen FB & De Luca CJ (1982). Muscle fatigue monitor: a noninvasive device for observing localized muscular fatigue. IEEE Trans Biomed Eng 29, 760 768.
55. Thomas CK, Woods JJ & Bigland-Ritchie B (1989). Impulse propagation and muscle activation in long maximal voluntary contractions. J Appl Physiol 67, 1835 1842.
56. Tibes U, Hemmer B, Boning D & Schweigart U (1976). Relationships of femoral venous [K+], PO2, osmolality, and [orthophosphate] with heart rate, ventilation, and leg blood flow during bicycle exercise in athletes and non-athletes. Eur J Appl Physiol Occup Physiol 35, 201 214.
57. Unsworth K, Hicks A & McKelvie R (1998). The effect of β-blockade on plasma potassium concentrations and muscle excitability following static exercise. Pflugers Arch 436, 449 456.
58. Vollestad NK, Hallen J & Sejersted OM (1994). Effect of exercise intensity on potassium balance in muscle and blood of man. J Physiol 475, 359 368.
59. West W, Hicks A, McKelvie R & O'Brien J (1996). The relationship between plasma potassium, muscle membrane excitability and force following quadriceps fatigue. Pflugers Arch 432, 43 49.
60. Yonemura K (1967). Resting and action potentials in red and white muscles of the rat. Jpn J Physiol 17, 708 719.
61. Zoladz JA, Duda K, Majerczak J & Thor P (2002). Effect of different cycling frequencies during incremental exercise on the venous plasma potassium concentration in humans. Physiol Res 51, 581 586.