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Volumn 30, Issue 6, 2007, Pages 723-732

β-Galactoside prodrugs of doxorubicin for application in antibody directed enzyme prodrug therapy/prodrug monotherapy

Author keywords

Doxorubicin; Hydrolysis; In vitro cytotoxicity; Prodrugs; Release kinetics; Stability

Indexed keywords


EID: 34347376957     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02977634     Document Type: Article
Times cited : (33)

References (24)
  • 3
    • 0023619243 scopus 로고
    • Antibody directed enzymes revive anti-cancer prodrugs concept
    • Bagshawe, K. D., Antibody directed enzymes revive anti-cancer prodrugs concept. Br. J. Cancer., 56, 531-532 (1987).
    • (1987) Br. J. Cancer , vol.56 , pp. 531-532
    • Bagshawe, K.D.1
  • 6
    • 0027942024 scopus 로고
    • Antibody-directed enzyme prodrug therapy
    • Bagshawe, K. D., Antibody-directed enzyme prodrug therapy. Clin. Pharmacokinet., 27, 368-376 (1994).
    • (1994) Clin. Pharmacokinet , vol.27 , pp. 368-376
    • Bagshawe, K.D.1
  • 8
    • 0001874589 scopus 로고
    • A novel one-step tumor-selective prodrug activation system
    • Bosslet, K., Czech, J., and Hoffmann, D., A novel one-step tumor-selective prodrug activation system. Tumor Targeting., 1, 45-50 (1995).
    • (1995) Tumor Targeting , vol.1 , pp. 45-50
    • Bosslet, K.1    Czech, J.2    Hoffmann, D.3
  • 9
    • 0016210929 scopus 로고
    • Enzyme activity in invasive tumors of human breast and colon
    • Bosmann, H. B. and Hall, T. C., Enzyme activity in invasive tumors of human breast and colon. Proc. Natl. Acad. Sci. U. S. A., 71, 1833-1837 (1974).
    • (1974) Proc. Natl. Acad. Sci. U. S. A , vol.71 , pp. 1833-1837
    • Bosmann, H.B.1    Hall, T.C.2
  • 10
    • 0019453510 scopus 로고    scopus 로고
    • Carl, P. L., Chakravarthy, P. K., and Katzenellenbogen, J. A., A novel linkage applicable in prodrug design. J. Med. Chem., 24, 479-480 (1981).
    • Carl, P. L., Chakravarthy, P. K., and Katzenellenbogen, J. A., A novel linkage applicable in prodrug design. J. Med. Chem., 24, 479-480 (1981).
  • 12
    • 0025370204 scopus 로고
    • Antibody-directed enzyme prodrug therapy
    • Connors, T. A., Antibody-directed enzyme prodrug therapy. Cancer Cells, 2, 56-57 (1990).
    • (1990) Cancer Cells , vol.2 , pp. 56-57
    • Connors, T.A.1
  • 14
    • 15144351951 scopus 로고    scopus 로고
    • Anthracycline-glycosyl prodrugs. Verfahren zu ihrer Herstellung und ihre Verwendung in Kombination mit functionalisierten tumorspezifischen Enzymconjugaten.
    • European Patent 91101096.5, 1991 28.01.91
    • Gerken, M., Krause, M., and Czech, J., Anthracycline-glycosyl prodrugs. Verfahren zu ihrer Herstellung und ihre Verwendung in Kombination mit functionalisierten tumorspezifischen Enzymconjugaten. European Patent 91101096.5, (1991) 28.01.91.
    • Gerken, M.1    Krause, M.2    Czech, J.3
  • 16
    • 0034686261 scopus 로고    scopus 로고
    • Ghosh, A. K., Khan, S., Frank Marini, J., and Nelson J. A., A daunorubicin β-galactoside prodrug for use in conjunction with gene-directed enzyme prodrug therapy. Tetrahedron Lett., 41, 4871-4874 (2000).
    • Ghosh, A. K., Khan, S., Frank Marini, J., and Nelson J. A., A daunorubicin β-galactoside prodrug for use in conjunction with gene-directed enzyme prodrug therapy. Tetrahedron Lett., 41, 4871-4874 (2000).
  • 17
    • 0141839804 scopus 로고    scopus 로고
    • Selective activation of anthracycline prodrugs for use in conjunction with ADEPT
    • HariKrishna, D., Rao, A. R., and Krishna, D. R., Selective activation of anthracycline prodrugs for use in conjunction with ADEPT. Drugs News and Perspect., 16, 309-318 (2003).
    • (2003) Drugs News and Perspect , vol.16 , pp. 309-318
    • HariKrishna, D.1    Rao, A.R.2    Krishna, D.R.3
  • 18
    • 0032764992 scopus 로고    scopus 로고
    • Does pH 6 beta-galactosidase activity indicate cell senescence?
    • Krishna, D. R., Sperker, B., Fritz, P., and Klotz, U., Does pH 6 beta-galactosidase activity indicate cell senescence?. Mech. Ageing Dev., 109, 113-123 (1999).
    • (1999) Mech. Ageing Dev , vol.109 , pp. 113-123
    • Krishna, D.R.1    Sperker, B.2    Fritz, P.3    Klotz, U.4
  • 19
    • 0027356104 scopus 로고
    • Lysosomes, lysosomal enzymes and cancer
    • Michael, J. B. and Tannock, I. F., Lysosomes, lysosomal enzymes and cancer. Adv. Cancer Res., 60, 269-291 (1993).
    • (1993) Adv. Cancer Res , vol.60 , pp. 269-291
    • Michael, J.B.1    Tannock, I.F.2
  • 20
  • 21
    • 0025174052 scopus 로고
    • Activation of prodrugs by antibody-enzyme conjugates: A new approach to cancer therapy
    • Senter, P. D., Activation of prodrugs by antibody-enzyme conjugates: a new approach to cancer therapy. FASEB J., 4, 188-193 (1990).
    • (1990) FASEB J , vol.4 , pp. 188-193
    • Senter, P.D.1
  • 22
    • 0035980983 scopus 로고    scopus 로고
    • Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates
    • Senter, P. D. and Springer, C. J., Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates. Adv. Drug Deliv. Rev., 53, 247-284 (2001).
    • (2001) Adv. Drug Deliv. Rev , vol.53 , pp. 247-284
    • Senter, P.D.1    Springer, C.J.2
  • 24
    • 0025880550 scopus 로고
    • Pharmacokinetic analysis or two-step approaches using bifunctional and enzyme conjugated antibodies
    • Yuan, F., Baxter, L., and Jai, R. K., Pharmacokinetic analysis or two-step approaches using bifunctional and enzyme conjugated antibodies. Cancer Res., 51, 3119-3130 (1991).
    • (1991) Cancer Res , vol.51 , pp. 3119-3130
    • Yuan, F.1    Baxter, L.2    Jai, R.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.