Expression and significance of TSG101, P21 and P300/CBP in squamous cell carcinoma and adenocarcinoma of the lung

Chinese Journal of Lung Cancer

Volumn 10, Issue 3, 2007, Pages 197-202

  Lu, Ping ^a   Zhang, Daorong ^a   Gao, Yanhua ^a   Hu, Chunying ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Lung neoplasms carcinoma; P21; P300 CBP; Protein expression; TSG101

Indexed keywords

HISTONE ACETYLTRANSFERASE PCAF; P21 ACTIVATED KINASE; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN;

ADULT; AGED; ARTICLE; CANCER STAGING; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG SQUAMOUS CELL CARCINOMA; LYMPH NODE METASTASIS; MALE; PARAMETER; PROTEIN EXPRESSION; TISSUE MICROARRAY; WESTERN BLOTTING;

EID: 34347374922     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Koonin EV, Abagyan RA. TSG101 may be the prototype of a class of dominant negative ubiquitin regulators. Nat Genet, 1997, 16(4): 330-331.
2. Thomson TM, Khalid H, Lozano JJ, et al. Role of UEV-1A, a homologue of the tumor suppressor protein TSG101, in protection from DNA damage. FEBS Lett, 1998, 423(1): 49-52.
3. Yao GY, Yang MT, Rong TH, et al. Significance of membrane type-1 matrix metalloproteinase expression in breast cancer. Chin J Cancer, 2004, 23(z1): 1482-1486.
4. Steiner P, Barnes DM, Harris WH, et al. Absence of rearrangements in the tumour susceptibility gene TSG101 in human breast cancer. Nat Genet, 1997, 16(4): 332-333.
5. Krempler A, Henry MD, Triplett AA, et al. Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death. J Biol Chem, 2002, 277(45): 43216-43223.
6. Cip1/WAF1. Proc Natl Acad Sci USA, 2002, 99(8): 5430-5435.
7. Bennett NA, Pattillo RA, Lin RS, et al. TSG101 expression in gynecological tumors: relationship to cyclin D1, cyclin E, p53 and p16 proteins. Cell Mol Biol (Noisy-le-grand), 2001, 47(7): 1187-1193.
8. Oh Y, Proctor ML, Fan YH, et al. TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer. Oncogene, 1998, 17(9): 1141-1148.
9. Turpin E, Dalle B, de Roquancourt A, et al. Stress-induced aberrant splicing of TSG101: association to high tumor grade and p53 status in breast cancers. Oncogene, 1999, 18(54): 7834-7837.
10. Feng GH, Lih CJ, Cohen SN. TSG101 protein steady-state level is regulated posttranslationally by an evolutionary conserved COOH-terminal sequence. Cancer Res, 2000, 60(6): 1736-1741.
11. Marchetti A, Doglioni C, Barbareschi M, et al. p21 RNA and protein expression in non-small cell lung carcinomas: evidence of p53-independent expression and association with tumoral differentiaion. Oncogene, 1996, 12(6): 1319-1324.
12. Akita K, Inagaki H, Sato S, et al. p185 (HER-2/neu) and p21 (CIP1/WAF1) expression in primary tumors and lymph node metastases in non-small cell lung cancer. Jpn J Cancer Res. 2002, 93 (9): 1007-1011.
13. Sun Z, Pan J, Hope WX, et al. Tumor susceptibility gene 101 protein represses androgen receptor transactivation and interacts with p300. Cancer, 1999, 86(4): 689-696.