Leptin infusion during the early luteal phase in ewes does not affect progesterone production

Domestic Animal Endocrinology

Volumn 33, Issue 2, 2007, Pages 240-244

  Nicklin, L T ^a   Robinson, R S ^a   Campbell, B K ^b   Hunter, M G ^a   Mann, G E ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Queens Medical Centre   (United Kingdom)

Author keywords

Corpus luteum; LH; Sheep

Indexed keywords

ESTRADIOL; LEPTIN; LUTEINIZING HORMONE; PROGESTERONE;

ANIMAL; ARTICLE; BLOOD; CORPUS LUTEUM; ESTRUS CYCLE; FEMALE; METABOLISM; OVULATION; PHYSIOLOGY; SHEEP;

ANIMALS; CORPUS LUTEUM; ESTRADIOL; ESTROUS CYCLE; FEMALE; LEPTIN; LUTEINIZING HORMONE; OVULATION; PROGESTERONE; SHEEP;

OVIS; OVIS ARIES;

EID: 34347348265     PISSN: 07397240     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.domaniend.2006.05.003     Document Type: Article

References (12)

1. Spicer L.J. Leptin: a possible metabolic signal affecting reproduction. Domest Anim Endocrinol 21 (2001) 251-270
2. Kendall N.R., Guitierrez C.G., Scaramuzzi R.J., Baird D.T., Webb R., and Campbell B.K. Direct in vivo effects of leptin on ovarian steroidogenesis in sheep. Reproduction 128 (2004) 757-765
3. Munoz-Gutierrez M., Findlay P.A., Adam C.L., Wax G., Campbell B.K., Kendall N.R., et al. The ovarian expression of mRNAs for aromatase, IGF-I receptor, IGF-binding protein-2, -4 and -5, leptin and leptin receptor in cycling ewes after three days of leptin infusion. Reproduction 130 (2005) 869-881
4. Nicklin L.T., Glister C., Robinson R.S., Marsters P., Campbell B.K., Knight P.G., et al. Leptin in the bovine corpus luteum-receptor expression and effects on progesterone production. Reprod Abstr Ser 31 (2004) O2
5. Goding J.R., McCracken J.A., and Baird D.T. The study of ovarian function in the ewe by means of a vascular autotransplantation technique. J Endocrinol 39 (1967) 37-52
6. Law A.S., Baxter G., Logue D.N., O'shea T., and Webb R. Evidence for the action of bovine follicular fluid factor(s) other than inhibin in suppressing follicular development and delaying oestrus in heifers. J Reprod Fertil 96 (1992) 603-616
7. Blache D., Tellam R.L., Chagas L.M., Blackberry M.A., Vercoe P.E., and Martin G.B. Level of nutrition affects leptin concentrations in plasma and cerebrospinal fluid in sheep. J Endocrinol 165 (2000) 625-637
8. Price C.A., Morris B.A., and Webb R. Reproductive and endocrine effects of active immunization against a testosterone conjugate in the heifer. J Reprod Fertil 81 (1987) 149-160
9. Webb R., Baxter G., McBride D., Nordblom G.D., and Shaw M.P. The measurement of testosterone and estradiol-17 beta using iodinated tracers and incorporating an affinity chromatography extraction procedure. J Steroid Biochem 23 (1985) 1043-1051
10. Spicer L.J., and Francisco C.C. The adipose obese gene product, leptin: evidence of a direct inhibitory role in ovarian function. Endocrinology 138 (1997) 3374-3379
11. Henry B.A., Goding J.W., Alexander W.S., Tilbrook A.J., Canny B.J., Dunshea F., et al. Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function. Endocrinology 140 (1999) 1175-1182
12. Morrison C.D., Wood R., McFadin E.L., Whitley N.C., and Keisler D.H. Effect of intravenous infusion of recombinant ovine leptin on feed intake and serum concentrations of GH, LH, insulin, IGF-1, cortisol, and thyroxine in growing prepubertal ewe lambs. Domest Anim Endocrinol 22 (2002) 103-112