-
1
-
-
33747378313
-
Therapeutic antibodies: Delivering the promise?
-
Hale, G. Therapeutic antibodies: Delivering the promise? Adv. Drug Delivery Rev. 58, 633-639 (2006).
-
(2006)
Adv. Drug Delivery Rev
, vol.58
, pp. 633-639
-
-
Hale, G.1
-
2
-
-
33747855481
-
Comparing antibody and small-molecule therapies for cancer
-
Kohzoh, I. & Akinori, T. Comparing antibody and small-molecule therapies for cancer. Nat. Rev. Cancer 6, 714-727 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 714-727
-
-
Kohzoh, I.1
Akinori, T.2
-
3
-
-
0038641840
-
A chemically programmed monoclonal antibody for cancer therapy. Adapter immunotherapy based on a covalent antibody catalyst
-
Rader, C., Sinha, S.C., Popkov, M., Lerner, R.A. & Barbas, C.F., III A chemically programmed monoclonal antibody for cancer therapy. Adapter immunotherapy based on a covalent antibody catalyst. Proc. Natl. Acad. Sci. USA 100, 5396-5400 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5396-5400
-
-
Rader, C.1
Sinha, S.C.2
Popkov, M.3
Lerner, R.A.4
Barbas III, C.F.5
-
4
-
-
33746642087
-
Breaking the one antibody one target axiom
-
Guo, F. et al. Breaking the one antibody one target axiom. Proc. Natl. Acad. Sci. USA 103, 11009-11014 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11009-11014
-
-
Guo, F.1
-
5
-
-
33746344379
-
Small molecule drug activity in melanoma models may be dramatically enhanced with an antibody effector
-
Popkov, M., Rader, C., Gonzalez, B., Sinha, S.C. & Barbas, C.F., III Small molecule drug activity in melanoma models may be dramatically enhanced with an antibody effector. Int. J. Cancer 119, 1194-1207 (2006).
-
(2006)
Int. J. Cancer
, vol.119
, pp. 1194-1207
-
-
Popkov, M.1
Rader, C.2
Gonzalez, B.3
Sinha, S.C.4
Barbas III, C.F.5
-
6
-
-
33846061734
-
Chemically programmed antibodies: Endothelin receptor targeting Cov X-Bodies
-
Doppalaudi, V.R. et. al. Chemically programmed antibodies: Endothelin receptor targeting Cov X-Bodies. Biorg. Med. Chem. Lett. 17, 501-506 (2006).
-
(2006)
Biorg. Med. Chem. Lett
, vol.17
, pp. 501-506
-
-
Doppalaudi, V.R.1
et., al.2
-
7
-
-
7444249590
-
Chemical-adaptor immunotherapy: Design, synthesis and evaluation of novel integrin-targeting devices
-
Li, L.-S. et. al. Chemical-adaptor immunotherapy: Design, synthesis and evaluation of novel integrin-targeting devices. J. Med. Chem. 47, 5630-5640 (2004).
-
(2004)
J. Med. Chem
, vol.47
, pp. 5630-5640
-
-
Li, L.-S.1
et., al.2
-
8
-
-
0029590066
-
Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes
-
Wagner, J., Lerner, R.A. & Barbas, C.F., III Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes. Science 270, 1797-1800 (1995).
-
(1995)
Science
, vol.270
, pp. 1797-1800
-
-
Wagner, J.1
Lerner, R.A.2
Barbas III, C.F.3
-
9
-
-
0041825381
-
A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy
-
Rader, C. et al. A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy. J. Mol. Biol. 332, 889-899 (2003).
-
(2003)
J. Mol. Biol
, vol.332
, pp. 889-899
-
-
Rader, C.1
-
10
-
-
0036007606
-
Preparation and functional evaluation of RGD-modified proteins as αvβ3 integrin directed therapeutics
-
Kok, R.J. et al. Preparation and functional evaluation of RGD-modified proteins as αvβ3 integrin directed therapeutics. Bioconjugate Chem. 13, 128-135 (2002).
-
(2002)
Bioconjugate Chem
, vol.13
, pp. 128-135
-
-
Kok, R.J.1
-
11
-
-
33846210997
-
Preclinical pharmacokinetics, tissue distribution, and antitumor activity of a folate-hapten conjugate-targeted immunotherapy in haptenimmunized mice
-
Lu, Y. et al. Preclinical pharmacokinetics, tissue distribution, and antitumor activity of a folate-hapten conjugate-targeted immunotherapy in haptenimmunized mice. Mol. Cancer Ther. 5, 3258-3267 (2006).
-
(2006)
Mol. Cancer Ther
, vol.5
, pp. 3258-3267
-
-
Lu, Y.1
-
12
-
-
0034609772
-
Nonpeptide αvβ3 antagonists. 1. Transformation of a potent, integrin-selective αIIbβ3 antagonist into a potent αvβ3 antagonist
-
Duggan, M.E. et al. Nonpeptide αvβ3 antagonists. 1. Transformation of a potent, integrin-selective αIIbβ3 antagonist into a potent αvβ3 antagonist. J. Med. Chem. 43, 3736-3745 (2000).
-
(2000)
J. Med. Chem
, vol.43
, pp. 3736-3745
-
-
Duggan, M.E.1
-
13
-
-
0032416718
-
Aldol sensors for the rapid generation of tunable fluorescence by antibody catalysis
-
List, B., Barbas, C.F., III & Lerner, R.A. Aldol sensors for the rapid generation of tunable fluorescence by antibody catalysis. Proc. Natl. Acad. Sci. USA 95, 15351-15355 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15351-15355
-
-
List, B.1
Barbas III, C.F.2
Lerner, R.A.3
|