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Volumn 56, Issue 7, 2007, Pages 1025-1026

Double resistance to imatinib and AMG 706 caused by multiple acquired KIT exon 17 mutations in a gastrointestinal stromal tumour [9]

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18; IMATINIB; PROTEIN TYROSINE KINASE; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; SUNITINIB;

EID: 34347271967     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2006.115923     Document Type: Letter
Times cited : (6)

References (9)
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  • 2
    • 15644363454 scopus 로고    scopus 로고
    • Gain-of-function mutations of c-kit in human gastrointestinal stromal rumors
    • Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal rumors. Science 1998;279:577-80.
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    • Hirota, S.1    Isozaki, K.2    Moriyama, Y.3
  • 3
    • 20344393896 scopus 로고    scopus 로고
    • Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation
    • Antonescu CR, Besmer P, Guo T, et al. Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. Clin Cancer Res 2005;11:4182-90.
    • (2005) Clin Cancer Res , vol.11 , pp. 4182-4190
    • Antonescu, C.R.1    Besmer, P.2    Guo, T.3
  • 4
    • 33646432734 scopus 로고    scopus 로고
    • Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate
    • Prenen H, Cools J, Mentens N, et al. Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate. Clin Cancer Res 2006;12:2622-7.
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    • Prenen, H.1    Cools, J.2    Mentens, N.3
  • 5
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    • Benjamin R, Schöffski P, Hartmann JT, et al. Initial results of a multicenter single arm phase 2 study of AMG 706, an oral multi-kinase inhibitor, for the treatment of advanced imatinib-resistant gastrointestinal stromal tumors (GIST). Oral presentation No 641 CTOS 12th Annual Meeting 2006. http://www.ctos.org (accessed 3 March 2007).
    • Benjamin R, Schöffski P, Hartmann JT, et al. Initial results of a multicenter single arm phase 2 study of AMG 706, an oral multi-kinase inhibitor, for the treatment of advanced imatinib-resistant gastrointestinal stromal tumors (GIST). Oral presentation No 641 CTOS 12th Annual Meeting 2006. http://www.ctos.org (accessed 3 March 2007).
  • 6
    • 33645693156 scopus 로고    scopus 로고
    • Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate
    • Wardelmann E, Merkelbach-Bruse S, Pauls K, et al. Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate. Clin Cancer Res 2006;12:1743-9.
    • (2006) Clin Cancer Res , vol.12 , pp. 1743-1749
    • Wardelmann, E.1    Merkelbach-Bruse, S.2    Pauls, K.3
  • 7
    • 20144387198 scopus 로고    scopus 로고
    • Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations
    • Wardelmann E, Thomas N, Merkelbach-Bruse S, et al. Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations. Lancet Oncol 2005;6:249-51.
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    • Wardelmann, E.1    Thomas, N.2    Merkelbach-Bruse, S.3
  • 8
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    • Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
    • Heinrich MC, Corless CL, Demetri GD, et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol 2003;21:4342-9.
    • (2003) J Clin Oncol , vol.21 , pp. 4342-4349
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  • 9
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    • Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
    • Schittenhelm MM, Shiraga S, Schroeder A, et al. Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies. Cancer Res 2006;66:473-81.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.