Pamidronate preserves bone mass for at least 2 years following acute administration for pediatric burn injury

Bone

Volumn 41, Issue 2, 2007, Pages 297-302

  Przkora, Rene ^a,b   Herndon, David N ^a,b   Sherrard, Donald J ^c   Chinkes, David L ^a,b   Klein, Gordon L ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Bone density; Bone mineral content; Burns; Pamidronate

Indexed keywords

PAMIDRONIC ACID; PLACEBO;

ADOLESCENT; ARTICLE; BONE BIOPSY; BONE DENSITOMETRY; BONE MASS; BONE MINERAL; BONE REMODELING; BURN; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; HUMAN TISSUE; HYPOCALCEMIA; ILIAC CREST; LUMBAR SPINE; MALE; MORPHOMETRICS; OSTEOID; OSTEOPOROSIS; RANDOMIZED CONTROLLED TRIAL;

BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; BURNS; CHILD; DIPHOSPHONATES; HUMANS; LUMBAR VERTEBRAE;

EID: 34347238909     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2007.04.195     Document Type: Article

References (18)

1. Herndon D.N., and Tompkins R.G. Support of the metabolic response to burn injury. Lancet 363 (2004) 1895-1900
2. Klein G.L., Herndon D.N., Langman C.B., Rutan T.C., Young W.E., Pembleton G., et al. Long-term reduction in bone mass following severe burn injury in children. J Pediatr 26 (1995) 252-256
3. Klein G.L., Herndon D.N., Goodman W.G., Langman C.B., Phillips W.A., Dickson I.R., et al. Histomorphometric and biochemical characterization of bone following acute severe burns in children. Bone 17 (1995) 455-460
4. Klein G.L., Bi L.X., Sherrard D.J., Beavan S.R., Ireland D., Compston J.E., et al. Evidence of supporting a role of glucocorticoids in short-term bone loss in burned children. Osteoporos Int 15 (2004) 468-474
5. Klein G.L., Nicolai M., Langman C.B., Cuneo B.F., Sailer D.E., and Herndon D.N. Dysregulations of calcium homeostasis following severe burn injury in children: possible role of magnesium depletion. J Pediatr 131 (1997) 246-251
6. Murphey E.D., Chattopadhyay N., Bai M., Kifor O., Harper D., Traber D.L., et al. Up-regulation of the parathyroid calcium-sensing receptor after burn injury in sheep: a potential contributory factor to post-burn hypocalcemia. Crit Care Med 28 (2000) 3885-3890
7. Klein G.L., Langman C.B., and Herndon D.N. Vitamin D depletion following burn injury in children: a possible factor in post-burn osteopenia. J Trauma 52 (2002) 346-350
8. Klein G.L., Chen T.C., Holick M.F., Langman C.B., Price H., Celis M.M., et al. Synthesis of vitamin D in skin after burns. Lancet 363 (2004) 291-292
9. Klein G.L., Langman C.B., and Herndon D.N. Persistent hypoparathyroidism following magnesium repletion in burn-injured children. Pediatr Nephrol 14 (2000) 301-304
10. Przkora R., Jeschke M.G., Barrow R.E., Suman O.E., Meyer W.J., Finnerty C.C., et al. Metabolic and hormonal changes of severely burned children receiving long-term oxandrolone treatment. Ann Surg 242 3 (2005) 384-389
11. Przkora R., Herndon D.N., Suman O.E., Jeschke M.G., Meyer W.J., Chinkes D.L., et al. Beneficial effects of extended growth hormone treatment after hospital discharge in pediatric burn patients. Ann Surg 243 (2006) 796-801
12. Klein G.L., Wimalawansa S.J., Kulkarni G., Sherrard D.J., Sanford A.P., Herndon D.N., et al. The efficacy of acute administration of pamidronate on the conservation of bone mass following severe burn injury in children: a double-blind randomized, controlled study. Osteoporos Int 16 (2005) 631-635
13. Glorieux F.H., Bishop N.J., Plotkin H., Chabot G., Lanoue G., and Travers R. Cyclic administration of pamidronate in children with severe osteogenesis imperfecta. N Engl J Med 339 (1998) 947-952
14. Arikoski P., Silverwood B., Tillmann V., and Bishop N.J. Intravenous pamidronate treatment in children with moderate to severe osteogenesis imperfecta: assessment of indices of dual-energy X-ray absorptiometry and bone metabolic markers during the first year of therapy. Bone 34 (2004) 539-546
15. Rauch F., Munns C., Land C., and Glorieux F.H. Pamidronate in children and adolescents with osteogenesis imperfecta: effect of treatment discontinuation. J Clin Endocrinol Metab 91 4 (2006) 1268-1274
16. Whyte M.P., Wenkert D., Clements K.L., McAlister W.H., and Mumm S. Bisphosphonate-induced osteopetrosis. N Engl J Med 349 (2003) 457-463
17. Low J.F., Herndon D.N., and Barrow R.E. Research letter: effect of growth hormone on growth delay in burned children: a 3-year follow-up study. Lancet 354 9192 (1999) 1789
18. Hart D.W., Herndon D.N., Klein G., Lee S.B., Celis M., and Mohan S. Attenuation of posttraumatic muscle catabolism and osteopenia by long-term growth hormone therapy. Ann Surg 233 (2001) 827-834