Brucellosis in 418 patients from the Balkan Peninsula: exposure-related differences in clinical manifestations, laboratory test results, and therapy outcome

International Journal of Infectious Diseases

Volumn 11, Issue 4, 2007, Pages 342-347

  Bosilkovski, Mile ^a   Krteva, Ljiljana ^a   Dimzova, Marija ^a   Kondova, Irena ^a  

^a SS CYRIL AND METHODIUS UNIVERSITY OF SKOPJE   (Macedonia)

Author keywords

Brucellosis; Occupational exposure; Relapse; Risk factor

Indexed keywords

ANTIINFECTIVE AGENT; C REACTIVE PROTEIN; CEFTRIAXONE; CIPROFLOXACIN; COTRIMOXAZOLE; DOXYCYCLINE; GENTAMICIN; RIFAMPICIN;

ADULT; ANAMNESIS; ANEMIA; ANTIGEN ANTIBODY COMPLEX; ARTHRALGIA; ARTICLE; BRUCELLOSIS; CIRCULATION; CLINICAL FEATURE; CONTROLLED STUDY; DEMOGRAPHY; DIAGNOSTIC PROCEDURE; ENDEMIC DISEASE; FEMALE; FEVER; HEALTH CENTER; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; OCCUPATIONAL EXPOSURE; PREVALENCE; RECURRENT DISEASE; TREATMENT FAILURE; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BRUCELLA; BRUCELLOSIS; CHEESE; CHILD; CHILD, PRESCHOOL; ENDEMIC DISEASES; FEMALE; HUMANS; INFANT; MACEDONIA (REPUBLIC); MALE; MIDDLE AGED; MILK; OCCUPATIONAL EXPOSURE; TREATMENT OUTCOME; ZOONOSES;

EID: 34347237630     PISSN: 12019712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijid.2006.10.002     Document Type: Article

References (30)

1. Morelli D. Control of major zoonoses: definition of priorities; methodology; analysis of resources available; evaluation of the results. Proceedings of the WHO/MZCP Workshop on zoonoses surveillance and control in the Mediterranean region; 30-31 March 1998; Cephalonia, Greece. Athens, Greece: WHO Mediterranean Zoonoses Control Centre; 1998, p. 7-9. (DOC/MZCP/ZOON/98.1).
2. FAO/WHO/OIE guidelines for a regional brucellosis control programme for the Middle East. Prepared at a special Workshop; 14-17 February 1993; Amman, Jordan. Amended at the round-table on the use of Rev-1 vaccine in small ruminants and cattle; 21-22 September 1995, Maisons-Alfort, France: FAO and CNEVA; 1995.
3. Godfroid J., Cloeckaert A., Liautard J.P., Kohler S., Fretin D., Walravens K., et al. From the discovery of the Malta fever's agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis. Vet Res 36 (2005) 313-326
4. Araj G.F. Human brucellosis: a clinical infectious disease with persistent diagnostic challenges. Clin Lab Sci 12 (1999) 207-212
5. Wallach J.C., Samartino L.E., Efron A., and Baldi P.C. Human infection by Brucella melitensis: an outbreak attributed to contact with infected goats. FEMS Immunol Med Microbiol 19 (1998) 315-321
6. Buchanan T.M., Hendricks S.L., Patton C.M., and Feldman R.A. Brucellosis in the United States, 1960-1972. An abattoir-associated disease. Part III. Epidemiology and evidence for acquired immunity. Medicine (Baltimore) 53 (1974) 427-439
7. Kubler P.A., and Klestov A.C. Osteoarticular brucellosis with long latent period. Clin Rheumatol 20 (2001) 444-446
8. Bosilkovski M., Krteva L.J., Caparoska S., and Dimzova M. Osteoarticular involvement in brucellosis: study of 196 cases in the Republic of Macedonia. Croat Med J 45 (2004) 727-733
9. Bosilkovski M., Krteva L.J., Caparoska S., and Dimzova M. Hip arthritis in brucellosis: a study of 33 cases in the Republic of Macedonia (FYROM). Int J Clin Pract 58 (2004) 1023-1027
10. Aygen B., Doganay M., Sumerkan B., Yildiz O., and Kayabas U. Clinical manifestations, complications and treatment of brucellosis: a retrospective evaluation of 480 patients. Med Malad Infect 32 (2002) 485-493
11. Hasanjani Roushan M.R., Mohrez M., Smailnejad Gangi S.M., Soleimani Amiri M.J., and Hajiahmedi M. Epidemiological features and clinical manifestations in 469 adult patients with brucellosis in Babol, Northern Iran. Epidemiol Infect 132 (2004) 1109-1114
12. Colmenero J.D., Reguera J.M., Martos F., Sanchez-De-Mora D., Delgado M., Causse M., et al. Complications associated with Brucella melitensis infection: a study of 530 cases. Medicine (Baltimore) 75 (1996) 195-211
13. Troy S.B., Rickman L.S., and Davis C.E. Brucellosis in San Diego. Epidemiology and species-related differences in acute clinical presentations. Medicine (Baltimore) 84 (2005) 174-187
14. Pappas G., Bosilkovski M., Akritidis N., Mastora M., Krteva L.J., and Tsianos E. Brucellosis and the respiratory system. Clin Infect Dis 37 (2003) e95-e99
15. Dokuzoguz B., Ergonul O., Baykam N., Esener H., Kilic S., Celikbas A., et al. Characteristics of B. melitensis versus B. abortus bacteremias. J Infect 50 (2005) 41-45
16. Pappas G., Akritidis N., Bosilkovski M., Tsianos E., and Brucellosis. N Engl J Med 352 (2005) 2325-2336
17. Rigatos G.A., and Kappos-Rigatou I. [The clinical features of brucellosis in an endemic area (author's transl)]. Wien Klin Wochenschr 89 (1977) 43-45
18. Andriopoulos P., Tsironi M., Deftereos S., Aessopos A., and Assimakopoulos G. Acute brucellosis: presentation, diagnosis, and treatment of 144 cases. Int J Infect Dis (2006) Apr 29; [Epub ahead of print]
19. Pfischner W.C.E., Ishak K.G., Neptune E.M., Fox S.M., Farid Z., and El Din G.N. Brucellosis in Egypt. A review of experience with 228 patients. Am J Med 6 (1957) 915-929
20. Mousa A.R.M., Elhag K.M., Khogali M., and Marafie A.A. The nature of human brucellosis in Kuwait: study of 379 cases. Rev Infect Dis 10 (1988) 211-217
21. Lulu A.R., Araj G.F., Khateeb M.I., Mustafa M.Y., Yusuf A.R., and Fenech F.F. Human brucellosis in Kuwait: a prospective study of 400 cases. Q J Med 66 (1988) 39-54
22. Benjamin B., Annobil S.H., and Khan M.R.H. Osteoarticular complications of childhood brucellosis: a study of 57 cases in Saudi Arabia. J Pediatr Orthop 12 (1992) 801-805
23. Malik G.M. A clinical study of brucellosis in adults in the Asir region of Saudi Arabia. Am J Trop Med Hyg 56 (1997) 375-377
24. Gur A., Geyik M.F., Dikici B., Nas K., Cevik R., Sarac J., et al. Complications of brucellosis in different age groups: a study of 283 cases in Southeastern Anatolia of Turkey. Yonsei Med J 44 (2003) 33-44
25. Pappas G., Papadimitrou P.H., Akritidis N., Christou L., and Tsianos E.V. The new global map of human brucellosis. Lancet Infect Dis 6 (2006) 91-99
26. Sadler W.W. Present evidence on the role of meat in the epidemiology of human brucellosis. Am J Pub Health 50 (1960) 504-514
27. Buchanan T.M., Faber L.C., and Feldman R.A. Brucellosis in the United States, 1960-1972. An abattoir-associated disease. Part I. Clinical features and therapy. Medicine (Baltimore) 53 (1974) 403-413
28. Spink W.W. Host-parasite relationship in brucellosis. Lancet 2 (1964) 161-164
29. Young E.J. An overview of human brucellosis. Clin Infect Dis 21 (1995) 283-290
30. Solera J., Rodriguez-Zapata M., Geijo P., Largo J., Paulino J., Saez L., et al. Doxycycline-rifampin versus doxycycline-streptomycin in treatment of human brucellosis due to Brucella melitensis. Antimicrob Agents Chemother 39 (1995) 2061-2067