Single cell diagnosis using comparative genomic hybridization after preliminary DNA amplification still needs more tweaking: too many miscalls

Fertility and Sterility

Volumn 88, Issue 1, 2007, Pages 247-248

  Fragouli, Elpida ^a   Delhanty, Joy D A ^b   Wells, Dagan ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; BLASTOMERE; CHROMOSOME ANALYSIS; CLINICAL PROTOCOL; COMPARATIVE GENOMIC HYBRIDIZATION; EMBRYO TRANSFER; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; HUMAN; KARYOTYPE; LETTER; MEIOSIS; PREGNANCY; PRIORITY JOURNAL;

ADULT; ANEUPLOIDY; CYTOGENETIC ANALYSIS; DNA REPLICATION; FEMALE; HUMANS; NUCLEIC ACID AMPLIFICATION TECHNIQUES; NUCLEIC ACID HYBRIDIZATION; PREIMPLANTATION DIAGNOSIS;

EID: 34347204878     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.03.013     Document Type: Letter

References (5)

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2. Fragouli E., Wells D., Thornhill A., Serhal P., Faed M.J., Harper J.C., and Delhanty J.D. Comparative genomic hybridization analysis of human oocytes and polar bodies. Hum Reprod 21 (2006) 2319-2328
3. Guitiérrez-Mateo C., Wells D., Benet J., Sanchez-Garcia J.F., Bermudez M.G., Belil I., et al. Reliability of comparative genomic hybridization to detect chromosome abnormalities in first polar bodies and metaphase II oocytes. Hum Reprod 19 (2004) 2118-2125
4. Sandalinas M., Márquez C., and Munne S. Spectral karyotyping of fresh, non-inseminated oocytes. Mol Hum Reprod 8 (2002) 580-585
5. Pellestor F., Andréo B., Arnal F., Humeau C., and Demaille J. Maternal aging and chromosomal abnormalities: new data from in vitro fertilized human oocytes. Hum Genet 112 (2003) 195-203