Identification and characterization of human ribokinase and comparison of its properties with E. coli ribokinase and human adenosine kinase

FEBS Letters

Volumn 581, Issue 17, 2007, Pages 3211-3216

  Park, Jae ^a   van Koeverden, Paul ^a   Singh, Bhag ^a   Gupta, Radhey S ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Adenosine kinase; Inhibitors and activators of adenosine kinase and ribokinase; PfkB family of proteins; Phosphate dependency; Ribokinase; Ribose metabolism

Indexed keywords

ADENOSINE KINASE; ADENOSINE KINASE INHIBITOR; ADENOSINE TRIPHOSPHATE; ARABINOSE; COMPLEMENTARY DNA; ENZYME ACTIVATOR; FRUCTOSE; GALACTOSE; PHOSPHATE; PHOSPHOTRANSFERASE; RECOMBINANT PROTEIN; RIBOKINASE; RIBOSE; RIBOSE 5 PHOSPHATE; UNCLASSIFIED DRUG; XYLOSE;

ARTICLE; CARBOHYDRATE METABOLISM; CATALYSIS; CATALYST; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

ADENOSINE KINASE; AMINO ACID SEQUENCE; DNA, COMPLEMENTARY; ENZYME ACTIVATION; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SEQUENCE HOMOLOGY, AMINO ACID;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 34250899753     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.06.009     Document Type: Article

References (22)

1. Barsotti C., and Ipata P.L. Pathways for alpha-d-ribose utilization for nucleobase salvage and 5-fluorouracil activation in rat brain. Biochem. Pharmacol. 63 (2002) 117-122
2. Brown A.K., Raeside D.L., Bowditch J., and Dow J.W. Metabolism and salvage of adenine and hypoxanthine by myocytes isolated from mature rat heart. Biochim. Biophys. Acta 845 (1985) 469-476
3. St Cyr J.A., Bianco R.W., Schneider J.R., Mahoney Jr. J.R., Tveter K., Einzig S., and Foker J.E. Enhanced high energy phosphate recovery with ribose infusion after global myocardial ischemia in a canine model. J. Surg. Res. 46 (1989) 157-162
4. Zimmer H.G., and Ibel H. Ribose accelerates the repletion of the ATP pool during recovery from reversible ischemia of the rat myocardium. J. Mol. Cell Cardiol. 16 (1984) 863-866
5. Muller C., Zimmer H., Gross M., Gresser U., Brotsack I., Wehling M., and Pliml W. Effect of ribose on cardiac adenine nucleotides in a donor model for heart transplantation. Eur. J. Med. Res. 3 (1998) 554-558
6. Salerno C., D'Eufemia P., Finocchiaro R., Celli M., Spalice A., Iannetti P., Crifo C., and Giardini O. Effect of d-ribose on purine synthesis and neurological symptoms in a patient with adenylosuccinase deficiency. Biochim. Biophys. Acta 1453 (1999) 135-140
7. Bork P., Sander C., and Valencia A. Convergent evolution of similar enzymatic function on different protein folds: the hexokinase, ribokinase, and galactokinase families of sugar kinases. Protein Sci. 2 (1993) 31-40
8. Sigrell J.A., Cameron A.D., Jones T.A., and Mowbray S.L. Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 A resolution: insights into a new family of kinase structures. Structure 6 (1998) 183-193
9. Mathews I.I., Erion M.D., and Ealick S.E. Structure of human adenosine kinase at 1.5 A resolution. Biochemistry 37 (1998) 15607-15620
10. Chuvikovsky D.V., Esipov R.S., Skoblov Y.S., Chupova L.A., Muravyova T.I., Miroshnikov A.I., Lapinjoki S., and Mikhailopulo I.A. Ribokinase from E. coli: expression, purification, and substrate specificity. Bioorg. Med. Chem. 14 (2006) 6327-6332
11. Maj M.C., and Gupta R.S. The effect of inorganic phosphate on the activity of bacterial ribokinase. J. Protein Chem. 20 (2001) 139-144
12. Sigrell J.A., Cameron A.D., Jones T.A., and Mowbray S.L. Purification, characterization, and crystallization of Escherichia coli ribokinase. Protein Sci. 6 (1997) 2474-2476
13. Agranoff B.W., and Brady R.O. Purification and properties of calf liver ribokinase. J. Biol. Chem. 219 (1956) 221-229
14. Maj M.C., Singh B., and Gupta R.S. Pentavalent ions dependency is a conserved property of adenosine kinase from diverse sources: identification of a novel motif implicated in phosphate and magnesium ion binding and substrate inhibition. Biochemistry 41 (2002) 4059-4069
15. Wharton C.W., and Eisenthal R. Molecular Enzymology (1981), Wiley
16. Baldauf S.L., Roger A.J., Wenk-Siefert I., and Doolittle W.F. A kingdom-level phylogeny of eukaryotes based on combined protein data. Science 290 (2000) 972-977
17. Park J., Singh B., Maj M.C., and Gupta R.S. Phosphorylated derivatives that activate or inhibit mammalian adenosine kinase provide insights into the role of pentavalent ions in AK catalysis. Protein J. 23 (2004) 167-177
18. Park J., Singh B., and Gupta R.S. Inhibition of adenosine kinase by phosphonate and bisphosphonate derivatives. Mol. Cell Biochem. 283 (2006) 11-21
19. Smolenski R.T., Kalsi K.K., Zych M., Kochan Z., and Yacoub M.H. Adenine/ribose supply increases adenosine production and protects ATP pool in adenosine kinase-inhibited cardiac cells. J. Mol. Cell Cardiol. 30 (1998) 673-683
20. Laloux M., Van Schaftingen E., Francois J., and Hers H.G. Phosphate dependency of phosphofructokinase 2. Eur. J. Biochem. 148 (1985) 155-159
21. Switzer R.L. Regulation and mechanism of phosphoribosylpyrophosphate synthetase. I. Purification and properties of the enzyme from Salmonella typhimurium. J. Biol. Chem. 244 (1969) 2854-2863
22. 2+ ion and effect of phosphate on the activity of Escherichia coli phosphofructokinase-2: regulatory properties of a ribokinase family member. Biochemistry 45 (2006) 9291-9299