Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos

Journal of Immunology

Volumn 179, Issue 1, 2007, Pages 357-364

  Villablanca, Eduardo J ^a,b   Pistocchi, Anna ^c   Court, Felipe A ^d   Cotelli, Franco ^c   Bordignon, Claudio ^a   Allende, Miguel L ^e   Traversari, Catia ^f   Russo, Vincenzo ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^e UNIVERSITY OF CHILE   (Chile)

^f MOLMED S P A   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; IKAROS TRANSCRIPTION FACTOR; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN D2; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; PROSTAGLANDIN EP4A RECEPTOR; PROTEIN SCL; RAG1 PROTEIN; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; ISOPROTEIN; PROSTAGLANDIN E2 RECEPTOR, EP4 SUBTYPE; RAG 1 PROTEIN; RAG-1 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FERTILIZATION; FETOMATERNAL TRANSFUSION; HEMATOPOIESIS; LYMPHOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; STEM CELL; THYMUS; ZEBRA FISH; ANIMAL; BIOSYNTHESIS; CELL DIFFERENTIATION; CYTOLOGY; DRUG ANTAGONISM; IMMUNOLOGY; LYMPHOCYTE SUBPOPULATION; LYMPHOPOIESIS; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL; UPREGULATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL DIFFERENTIATION; CELL PROLIFERATION; DINOPROSTONE; HEMATOPOIESIS; HOMEODOMAIN PROTEINS; LYMPHOCYTE SUBSETS; LYMPHOPOIESIS; PROTEIN ISOFORMS; RECEPTORS, PROSTAGLANDIN E; SIGNAL TRANSDUCTION; STEM CELLS; THYMUS GLAND; UP-REGULATION; ZEBRAFISH;

EID: 34250889280     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.179.1.357     Document Type: Article

References (38)

1. Hata, A. N., and R. M. Breyer. 2004. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol. Ther. 103: 147-166.
2. 2 synthases. Clin. Immunol. 119: 229-240.
3. Narumiya, S. 2003. Prostanoids in immunity: roles revealed by mice deficient in their receptors. Life Sci. 74: 391-395.
4. Harizi, H., and N. Gualde. 2005. The impact of eicosanoids on the crosstalk between innate and adaptive immunity: the key roles of dendritic cells. Tissue Antigens 65: 507-514.
5. Ushikubi, F., M. Hirata, and S. Narumiya. 1995. Molecular biology of prostanoid receptors; an overview. J. Lipid Mediators Cell Signal. 12: 343-359.
6. Appasamy, P. M., K. Pendino, R. R. Schmidt, K. P. Chepenik, M. B. Prystowsky, and D. Goldowitz. 1991. Expression of prostaglandin G/H synthase (cyclooxygenase) during murine fetal thymic development. Cell. Immunol. 137: 341-357.
7. Rocca, B., L. M. Spain, E. Pure, R. Langenbach, C. Patrono, and G. A. FitzGerald. 1999. Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development. J. Clin. Invest. 103: 1469-1477.
8. Xu, H., D. J. Izon, C. Loftin, and L. M. Spain. 2001. The COX-2 inhibitor NS-398 causes T-cell developmental disruptions independent of COX-2 enzyme inhibition. Cell. Immunol. 214: 184-193.
9. + T lymphoblasts. J. Immunol. 154: 1041-1047.
10. Trede, N. S., A. Zapata, and L. I. Zon. 2001. Fishing for lymphoid genes. Trends Immunol. 22: 302-307.
11. Boehm, T., C. C. Bleul, and M. Schorpp. 2003. Genetic dissection of thymus development in mouse and zebraflsh. Immunol. Rev. 195: 15-27.
12. Trede, N. S., D. M. Langenau, D. Traver, A. T. Look, and L. I. Zon. 2004. The use of zebraflsh to understand immunity. Immunity 20: 367-379.
13. Langenau, D. M., and L. I. Zon. 2005. The zebraflsh: a new model of T-cell and thymic development. Nat. Rev. Immunol. 5: 307-317.
14. Cha, Y. I., L. Solnica-Krezel, and R. N. DuBois. 2006. Fishing for prostanoids: deciphering the developmental functions of cyclooxygenase-derived prostaglandins. Dev. Biol. 289: 263-272.
15. Schorpp, M., M. Leicht, E. Nold, M. Hammerschmidt, A. Haas-Assenbaum, W. Wiest, and T. Boehm. 2002. A zebraflsh orthologue (whnb) of the mouse nude gene is expressed in the epithelial compartment of the embryonic thymic rudiment. Mech. Dev. 118: 179-185.
16. Willett, C. E., H. Kawasaki, C. T. Amemiya, S. Lin, and L. A. Steiner. 2001. Ikaros expression as a marker for lymphoid progenitors during zebraflsh development. Dev. Dyn. 222: 694-698.
17. Bhandoola, A., and A. Sambandam. 2006. From stem cell to T cell: one route or many? Nat. Rev. Immunol. 6: 117-126.
18. Davidson, A. J., and L. I. Zon. 2004. The 'definitive' (and 'primitive') guide to zebraflsh hematopoiesis. Oncogene 23: 7233-7246.
19. de Jong, J. L., and L. I. Zon. 2005. Use of the zebraflsh system to study primitive and definitive hematopoiesis. Annu. Rev. Genet. 39: 481-501.
20. Murayama, E., K. Kissa, A. Zapata, E. Mordelet, V. Briolat, H. F. Lin, R. I. Handin, and P. Herbomel. 2006. Tracing hematopoietic precursor migration to successive hematopoietic organs during zebraflsh development. Immunity 25: 963-975.
21. Solnica-Krezel, L., A. F. Schier, and W. Driever. 1994. Efficient recovery of ENU-induced mutations from the zebraflsh germline. Genetics 136: 1401-1420.
22. 2 receptor EP2 subtype. J. Biol. Chem. 269: 11873-11877.
23. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215: 403-410.
24. 2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes Dev. 20: 77-86.
25. Jowett, T., and L. Lettice. 1994. Whole-mount in situ hybridizations on zebraflsh embryos using a mixture of digoxigenin- and fluorescein-labelled probes. Trends Genet. 10: 73-74.
26. Court, F. A., D. L. Sherman, T. Pratt, E. M. Garry, R. R. Ribchester, D. F. Cottrell, S. M. Fleetwood-Walker, and P. J. Brophy. 2004. Restricted growth of Schwann cells lacking Cajal bands slows conduction in myelinated nerves. Nature 431: 191-195.
27. Willett, C. E., A. G. Zapata, N. Hopkins, and L. A. Steiner. 1997. Expression of zebraflsh rag genes during early development identifies the thymus. Dev. Biol. 182: 331-341.
28. Willett, C. E., A. Cortes, A. Zuasti, and A. G. Zapata. 1999. Early hematopoiesis and developing lymphoid organs in the zebraflsh. Dev. Dyn. 214: 323-336.
29. Parker, L., and D. Y. Stainier. 1999. Cell-autonomous and non-autonomous requirements for the zebraflsh gene cloche in hematopoiesis. Development 126: 2643-2651.
30. Grosser, T., S. Yusuff, E. Cheskis, M. A. Pack, and G. A. FitzGerald. 2002. Developmental expression of functional cyclooxygenases in zebraflsh. Proc. Natl. Acad. Sci. USA 99: 8418-8423.
31. Ekker, S. C., and J. D. Larson. 2001. Morphant technology in model developmental systems. Genesis 30: 89-93.
32. 2 induces apoptosis in resting immature and mature human lymphocytes: a c-Myc-dependent and Bcl-2-independent associated pathway. J. Pharmacol. Exp. Ther. 277: 1793-1800.
33. Lawson, N. D., and B. M. Weinstein. 2002. In vivo imaging of embryonic vascular development using transgenic zebraflsh. Dev. Biol. 248: 307-318.
34. Lam, S. H., H. L. Chua, Z. Gong, T. J. Lam, and Y. M. Sin. 2004. Development and maturation of the immune system in zebraflsh, Danio rerio: a gene expression profiling, in situ hybridization and immunological study. Dev. Comp. Immunol. 28: 9-28.
35. Juarez, M. A., F. Su, S. Chun, M. J. Kiel, and S. E. Lyons. 2005. Distinct roles for SCL in erythroid specification and maturation in zebraflsh. J. Biol. Chem. 280: 41636-41644.
36. Weiss, I. M., and S. A. Liebhaber. 1994. Erythroid cell-specific determinants of α-globin mRNA stability. Mol. Cell. Biol. 14: 8123-8132.
37. Pevny, L., C. S. Lin, V. D'Agati, M. C. Simon, S. H. Orkin, and F. Costantini. 1995. Development of hematopoietic cells lacking transcription factor GATA-1. Development 121: 163-172.
38. Galloway, J. L., R. A. Wingert, C. Thisse, B. Thisse, and L. I. Zon. 2005. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebraflsh embryos. Dev. Cell. 8: 109-116.