Functional characterization of cell lines for high-throughput screening of human neuromedin U receptor subtype 2 specific agonists using a luciferase reporter gene assay

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 67, Issue 1, 2007, Pages 284-292

  Li, Xinping ^a   Shen, Fuwen ^a   Zhang, Yuwu ^a   Zhu, Jiang ^a   Huang, Lu ^a   Shi, Qunfang ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

Cell based assay; G protein coupled receptor; Luciferase; NMU2 receptor; Reporter gene; Traditional Chinese herbs

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; DIMETHYL SULFOXIDE; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; LUCIFERASE; NEUROMEDIN C; NEUROMEDIN C RECEPTOR SUBTYPE 2 SPECIFIC AGONIST; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DENSITY; CELL LINE; CHINESE HERB; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; DATA INTERPRETATION, STATISTICAL; DIMETHYL SULFOXIDE; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; FORSKOLIN; GENES, REPORTER; HUMANS; INDICATORS AND REAGENTS; LUCIFERASES; LUMINESCENCE; MEMBRANE PROTEINS; PLASMIDS; PROMOTER REGIONS (GENETICS); RECEPTORS, NEUROTRANSMITTER; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS;

EID: 34250888773     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.01.004     Document Type: Article

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