Dihydrogenistein-producing bacterium TM-40 isolated from human feces

Food Science and Technology Research

Volumn 13, Issue 2, 2007, Pages 129-132

  Tamura, Motoi ^a   Ohnishi Kameyama, Mayumi ^a   Nakagawa, Hiroyuki ^a   Tsushida, Tojiro ^a  

^a NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

Author keywords

Dihydrogenistein; Genistein; Intestinal bacteria

Indexed keywords

BACTERIA (MICROORGANISMS); COPROBACILLUS CATENIFORMIS;

EID: 34250875299     PISSN: 13446606     EISSN: None     Source Type: Journal    
DOI: 10.3136/fstr.13.129     Document Type: Article

References (13)

1. Adlercreutz, H., Hockerstedt, K., Bannwart, C., Bloigu, S., Hamalainen, E., Fotsis, T. and Ollus, A. (1987). Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG). J. Steroid Biochem. 27, 1135-1144.
2. Bowey, E., Adlercreutz, H. and Rowland, I. (2003). Metabolism of isoflavones and lignans by the gut microflora: a study in germfree and human flora associated rats. Food Chem Toxicol. 41, 631-636.
3. Breinholt, V. and Larsen, J.C. (1998). Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF7 cell proliferation assay. Chem Res Toxicol. 11, 622-629.
4. Chang, Y.C. and Nair, M.G. (1995). Metabolism of daidzein and genistein by intestinal bacteria. J Nat Prod. 58, 1892-1896.
5. Coldham, N.G., Howells, L.C., Santi, A., Montesissa, C., Langlais, C., King, L.J., Macpherson, D.D. and Sauer, M.J. (1999). Biotransformation of genistein in the rat: elucidation of metabolite structure by product ion mass fragmentology. J Steroid Biochem Mol Biol. 70, 169-184.
6. Hur, H.G., Lay, J.O. Jr., Beger, R.D., Freeman, J.P. and Rafii, F. (2000). Isolation of human intestinal bacteria metabolizing the natural isoflavone glycosides daidzin and genistin. Arch Microbiol. 174, 422-428.
7. Joannou, G.E., Kelly, G.E., Reeder, A.Y., Waring, M. and Nelson, C. (1995). A urinary profile study of dietary phytoestrogens. The identification and mode of metabolism of new isoflavonoids. J Steroid Biochem Mol Biol. 54, 167-184.
8. Kuiper, G.G., Lemmen, J.G., Carlsson, B., Corton, J.C., Safe, S.H., van der Saag, P.T., van der Burg, B. and Gustafsson, J.A. (1998). Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology. 139, 4252-4263.
9. Rowland, I., Faughnan, M., Hoey, L., Wähälä, K., Williamson, G. and Cassidy, A. (2003). Bioavailability of phyto-oestrogens. Br J Nutr. 89, S45-S58.
10. Schoefer, L., Mohan, R., Braune, A., Birringer, M. and Blaut, M. (2002). Anaerobic C-ring cleavage of genistein and daidzein by Eubacterium ramulus. FEMS Microbiol Lett. 208, 197-202.
11. Setchell, K.D., Borriello, S.P., Hulme, P., Kirk, D.N. and Axelson, M. (1984). Nonsteroidal estrogens of dietary origin: possible roles in hormone-dependent disease. Am J Clin Nutr. 40, 569-578.
12. Shutt, D.A. and Cox, R.I. (1972). Steroid and phyto-oestrogen binding to sheep uterine receptors in vitro. J Endocrinol. 52, 299-310.
13. Tamura, M., Tsushida, T. and Shinohara, K. (2007) Isolation of an isoflavone-metabolizing, Clostridium-like bacterium, strain TM-40, from human faeces. Anaerobe. 13, 32-35.