Cerebral inflammatory response after fetal asphyxia and hyperoxic resuscitation in newborn sheep

Pediatric Research

Volumn 62, Issue 1, 2007, Pages 71-77

  Markus, Tina ^a   Hansson, Stefan ^a   Amer Wåhlin, Isis ^a   Hellström Westas, Lena ^a   Saugstad, Ola Didrik ^b   Ley, David ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; OXYGEN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BRAIN CORTEX; CONTROLLED STUDY; DELIVERY; ENCEPHALITIS; FETUS; FETUS HYPOXIA; HYPEROXIA; IN SITU HYBRIDIZATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; RESUSCITATION; SHEEP; UMBILICAL CORD; UPREGULATION; WHITE MATTER;

ANIMALS; ANIMALS, NEWBORN; ASPHYXIA; CEREBRAL CORTEX; CYTOKINES; FEMALE; FETUS; INFLAMMATION; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-1BETA; MOLECULAR SEQUENCE DATA; PREGNANCY; RESUSCITATION; SHEEP, DOMESTIC; TOLL-LIKE RECEPTORS;

EID: 34250852881     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e31811ead6e     Document Type: Article

References (26)

1. Graulich J, Hoffmann U, Maier RF, Ruscher K, Pomper JK, Ko HK, Gabriel S, Obladen M, Heinemann U 2002 Acute neuronal injury after hypoxia is influenced by the reoxygenation mode in juvenile hippocampal slice cultures. Brain Res Dev Brain Res 137:35-42
2. Munkeby BH, Borke WB, Bjornland K, Sikkeland LI, Borge GI, Halvorsen B, Saugstad OD 2004 Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets. Pediatr Res 56:783-790
3. Saugstad OD, Ramji S, Vento M 2005 Resuscitation of depressed newborn infants with ambient air or pure oxygen: a meta-analysis. Biol Neonate 87:27-34
4. Vento M, Asensi M, Sastre J, Lloret A, Garcia-Sala F, Vina J 2003 Oxidative stress in asphyxiated term infants resuscitated with 100% oxygen. J Pediatr 142:240-246
5. Vento M, Sastre J, Asensi MA, Vina J 2005 Room-air resuscitation causes less damage to heart and kidney than 100% oxygen. Am J Respir Crit Care Med 172:1393-1398
6. Felderhoff-Mueser U, Bittigau P, Sifringer M, Jarosz B, Korobowicz E, Mahler L, Piening T, Moysich A, Grune T, Thor F, Heumann R, Buhrer C, Ikonomidou C 2004 Oxygen causes cell death in the developing brain. Neurobiol Dis 17:273-282
7. Felderhoff-Mueser U, Sifringer M, Polley O, Dzietko M, Leineweber B, Mahler L, Baier M, Bittigau P, Obladen M, Ikonomidou C, Buhrer C 2005 Caspase-1-processed interleukins in hyperoxia-induced cell death in the developing brain. Ann Neurol 57:50-59
8. Kopp E, Medzhitov R 2003 Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol 15:396-401
9. Li M, Carpio DF, Zheng Y, Bruzzo P, Singh V, Ouaaz F, Medzhitov RM, Beg AA 2001 An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. J Immunol 166:7128-7135
10. Thorngren-Jerneck K, Ley D, Hellstrom-Westas L, Hernandez-Andrade E, Lingman G, Ohlsson T, Oskarsson G, Pesonen E, Sandell A, Strand SE, Werner O, Marsal K 2001 Reduced postnatal cerebral glucose metabolism measured by PET after asphyxia in near term fetal lambs. J Neurosci Res 66:844-850
11. Bradley DJ, Towle HC, Young WS3rd 1992 Spatial and temporal expression of alpha- and beta-thyroid hormone receptor mRNAs, including the beta 2-subtype, in the developing mammalian nervous system. J Neurosci 12:2288-2302.
12. Ley D, Oskarsson G, Bellander M, Hernandez-Andrade E, Lingman G, Marsal K, Olsson T, Pesonen E, Thorngren-Jerneck K, Werner O, Hellstrom-Westas L 2004 Different responses of myocardial and cerebral blood flow to cord occlusion in exteriorized fetal sheep. Pediatr Res 55:568-575
13. Hagberg H, Gilland E, Bona E, Hanson LA, Hahin-Zoric M, Blennow M, Holst M, McRae A, Soder O 1996 Enhanced expression of interleukin (IL)-1 and IL-6 messenger RNA and bioactive protein after hypoxia-ischemia in neonatal rats. Pediatr Res 40:603-609
14. Cai Z, Pang Y, Lin S, Rhodes P 2003 Differential roles of tumor necrosis factor-a and interleukin-1b in lipopolysaccharide-induced brain injury in the neonatal rat. Brain Res 975:37-47
15. Loddick SA, Rothwell NJ 1996 Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab 16:932-940
16. Quan N, Stern EL, Whiteside MB, Herkenham M 1999 Induction of proinflammatory cytokine mRNAs in the brain after peripheral injection of subseptic doses of lipopolysaccharide in the rat. J Neuroimmunol 93:72-80
17. Trinchieri G 1998 Immunobiology of interleukin-12. Immunol Res 17:269-278
18. Yamada M, Kubo H, Kobayashi S, Ishizawa K, Sasaki H 2004 Interferon-gamma: a key contributor to hyperoxia-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol 287:L1042-L1047
19. Suzumura A, Sawada M, Takayanagi T 1998 Production of interleukin-12 and expression of its receptors by murine microglia. Brain Res 787:139-142
20. Bright JJ, Musuro BF, Du C, Sriram S 1998 Expression of IL-12 in CNS and lymphoid organs of mice with experimental allergic encephalitis. J Neuroimmunol 82:22-30
21. Olson JK, Miller SD 2004 Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol 173:3916-3924
22. Oyama J, Blais C Jr., Liu X, Pu M, Kobzik L, Kelly RA, Bourcier T 2004 Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice. Circulation 109:784-789
23. Brightbill HD, Libraty DH, Krutzik SR, Yang RB, Belisle JT, Bleharski JR, Maitland M, Norgard MV, Plevy SE, Smale ST, Brennan PJ, Bloom BR, Godowski PJ, Modlin RL 1999 Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 285:732-736
24. Dohlen G, Carlsen H, Blomhoff R, Thaulow E, Saugstad OD 2005 Reoxygenation of hypoxic mice with 100% oxygen induces brain nuclear factor-kappa B. Pediatr Res 58:941-945
25. Ohashi K, Burkart V, Flohe S, Kolb H 2000 Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 164:558-561
26. Termeer CC, Hennies J, Voith U, Ahrens T, Weiss JM, Prehm P, Simon JC 2000 Oligosaccharides of hyaluronan are potent activators of dendritic cells. J Immunol 165:1863-1870