Intoxication with a tricyclic antidepressant;Intoxikation mit einem trizyklischen antidepressivum

Anaesthesist

Volumn 56, Issue 6, 2007, Pages 581-586

  Sakka, S G ^a   Kuethe, F ^b   Demme, U ^c   Huttemann E ^d  

^a KRANKENHAUS MERHEIM   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d Klinikum Worms   (Germany)

Author keywords

Hemoperfusion; Intoxication; Tricyclic antidepressant

Indexed keywords

DOXEPIN; TRICYCLIC ANTIDEPRESSANT AGENT; ZOLPIDEM;

ACUTE RESPIRATORY FAILURE; ADULT; CASE REPORT; CLINICAL FEATURE; COMATOSE PATIENT; CYANOSIS; DISEASE COURSE; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG INTOXICATION; EMERGENCY PHYSICIAN; EMERGENCY WARD; ENDOTRACHEAL INTUBATION; FEMALE; GENERAL CONDITION IMPROVEMENT; GRAND MAL SEIZURE; HEMODIALYSIS; HEMOPERFUSION; HUMAN; MAJOR DEPRESSION; POISON CENTER; REVIEW; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANTIDEPRESSIVE AGENTS, TRICYCLIC; DEPRESSIVE DISORDER, MAJOR; DOXEPIN; FEMALE; HEMOPERFUSION; HUMANS; MIDDLE AGED; OVERDOSE; RENAL DIALYSIS; RESPIRATION, ARTIFICIAL; SEIZURES; SUICIDE, ATTEMPTED;

EID: 34250842618     PISSN: 00032417     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00101-007-1191-z     Document Type: Review

References (28)

1. Amitai Y, Erickson T, Kennedy EJ et al. (1993) Tricyclic antidepressants in red cells and plasma: correlation with impaired intraventricular conduction in acute overdose. Clin Pharmacol Ther 54: 219-227
2. Ash SR, Levy H, Akmal M et al. (2002) Treatment of severe tricyclic antidepressant overdose with extracorporeal sorbent detoxification. Adv Ren Replace Ther 9: 31-41
3. Bateman DN, Chick J, Good AM et al. (2004) Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose? Eur J Clin Pharmacol 60: 221-224
4. Baumann P, Hiemke C, Ulrich S et al. (2004) The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in psychiatry. Pharmacopsychiatry 37: 243-265
5. Battersby MW, O'Mahoney JJ, Beckwith AR, Hunt JL (1996) Antidepressant deaths by overdose. Aust N Z J Psychiatry 30: 223-228
6. Bramble MG, Lishman AH, Purdon J et al. (1985) An analysis of plasma levels and 24-hour ECG recordings in tricyclic antidepressant poisoning: implications for management. Q J Med 56: 357-366
7. Broocks A, Junghanns K, Thiel A et al. (2000) Neue Antidepressiva im Vergleich zu klassischen Trizyklika. Wirkmechanismen und klinische Beurteilung. Fortschr Neurol Psychiatr 68: 17-24
8. Buckley NA, Dawson AH, Whyte IM, Henry DA (1994) Greater toxicity in overdose of dothiepin than of other tricyclic antidepressants. Lancet 343: 159-162
9. Buckley NA, McManus PR (2002) Fatal toxicity of serotoninergic and other antidepressant drugs: analysis of United Kingdom mortality data. BMJ 325: 1332-1333
10. Charlier C, Pinto E, Ansseau M, Plomteux G (2002) Venlafaxine: the relationship between dose, plasma concentration and clinical response in depressive patients. J Psychopharmacol 16: 369-372
11. Cordonnier J, Heyndrickx A, Jordaens L et al. (1983) A fatal intoxication due to doxepin. J Anal Toxicol 7: 161-164
12. Dargan PI, Colbridge MG, Jones AL (2005) The management of tricyclic antidepressant poisoning: the role of gut decontamination, extracorporeal procedures and fab antibody fragments. Toxicol Rev 24: 187-194
13. Frank RD, Kierdorf HP (2000) Is there a role for hemoperfusion/ hemodialysis as a treatment option in severe tricyclic antidepressant intoxication? Int J Artif Organs 23: 618-623
14. Frommer DA, Kulig KW, Marx JA, Rumack B (1987) Tricyclic antidepressant overdose. A review. JAMA 257: 521-526
15. Goldgran-Toledano D, Sideris G, Kevorkian JP (2002) Overdose of cyclic antidepressants and the Brugada syndrome. N Engl J Med 346: 1591-1592
16. Harrigan RA, Brady WJ (1999) ECG abnormalities in tricyclic antidepressant ingestion. Am J Emerg Med 17: 387-393
17. Hiemke C, Dragicevic A, Grunder G et al. (2004) Therapeutic monitoring of new antipsychotic drugs. Ther Drug Monit 26: 156-160
18. Jick SS, Dean AD, Jick H (1995) Antidepressants and suicide. BMJ 310: 215-218
19. Karkkainen S, Neuvonen PJ (1986) Pharmacokinetics of amitriptyline influenced by oral charcoal and urine pH. Int J Clin Pharmacol Ther Toxicol 24: 326-332
20. Koski A, Vuori E, Ojanpera I (2005) Newer antidepressants: evaluation of fatal toxicity index and interaction with alcohol based on Finnish postmortem data. Int J Legal Med 119: 344-348
21. Levine B, Wu SC, Smialek JE (1999) Zolpidem distribution in postmortem cases. J Forensic Sci 44: 369-371
22. Meeker JE, Som CW, Macapagal EC, Benson PA (1995) Zolpidem tissue concentrations in a multiple drug related death involving Ambien. J Anal Toxicol 19: 531-534
23. Musshoff F, Grellner W, Madea B (1999) Toxicologic findings in suicide with doxepin and paroxetine. Arch Kriminol 204: 28-32
24. Pentel PR, Keyler DE, Brunn GJ et al. (1991) Redistribution of tricyclic antidepressants in rats using a drug-specific monoclonal antibody: dose-response relationship. Drug Metab Dispos 19: 24-28
25. Pfeiffer T, Bauer F, Hegerl U (2005) The German research network on depression and suicidality. Arch Suicide Res 9: 3-9
26. Retterstol N (1993) Death due to overdose of antidepressants: experiences from Norway. Acta Psychiatr Scand Suppl 371: 28-32
27. Slordal L, Lundgren TI, Bessesen A, Sager G (1987) Distribution of nortriptyline in human blood: effects of temperature, pH, and drug concentration. Ther Drug Monit 9: 67-71
28. Winek CL, Wahba WW, Janssen JK et al. (1996) Acute overdose of zolpidem. Forensic Sci Int 78: 165-168