Changes in pain perception and descending inhibitory controls start at middle age in healthy adults

Clinical Journal of Pain

Volumn 23, Issue 6, 2007, Pages 506-510

  Larivière, Marianne ^a   Goffaux, Philippe ^b   Marchand, Serge ^a,b,c   Julien, Nancy ^a  

^a UNIVERSITÉ DU QUÉBEC EN ABITIBI TÉMISCAMINGUE   (Canada)

^b UNIVERSITY OF SHERBROOKE   (Canada)

^c CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE   (Canada)

Author keywords

Aging; Diffuse noxious inhibitory controls (DNICs); Elderly; Pain; Pain modulation

Indexed keywords

ADULT; AGED; ARTICLE; COLD PRESSOR TEST; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MIDDLE AGED; NOCICEPTION; NOCICEPTIVE STIMULATION; NORMAL HUMAN; PAIN THRESHOLD; PRIORITY JOURNAL;

EID: 34250782209     PISSN: 07498047     EISSN: None     Source Type: Journal    
DOI: 10.1097/AJP.0b013e31806a23e8     Document Type: Article

References (24)

1. Melding PS. Is there such a thing as geriatric pain? Pain. 1991; 46:119-121.
2. Harkins SW. Geriatric pain. Pain perceptions in the old. Clin Geriatr Med. 1996;12:435-459.
3. Helme RD, Gibson SJ. The epidemiology of pain in elderly people. Clin Geriatr Med. 2001;17:417-431.
4. Kendig H, Browning CJ, Young AE. Impacts of illness and disability on the well-being of older people. Disabil Rehabil. 2000; 22:15-22.
5. Roy R. A psychosocial perspective on chronic pain and depression in the elderly. Social Work in Health Care. 1986;12:27-36.
6. Kennedy GJ, Kelman HR, Thomas C. The emergence of depressive symptoms in late life: the importance of declining health and increasing disability. J Community Health. 1990;15:93-104.
7. Edwards RR, Fillingim RB, Ness TJ. Age-related differences in endogenous pain modulation: a comparison of diffuse noxious inhibitory controls in healthy older and younger adults. Pain. 2003; 101:155-165.
8. Washington LL, Gibson SJ, Helme RD. Age-related differences in the endogenous analgesic response to repeated cold water immersion in human volunteers. Pain. 2000;89:89-96.
9. Goffaux P, Redmond WJ, Rainville P, et al. Descending analgesiawhen the Spine echoes what the brain expects. Pain. 2007. In press.
10. Wager TD, Rilling JK, Smith EE, et al. Placebo-induced changes in fMRI in the anticipation and experience of pain. Science. 2004; 303:1162-1167.
11. Gibson SJ, Katz B, Corran TM, et al. Pain in older persons. Disabil Rehabil. 1994;16:127-139.
12. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189-198.
13. Hofbauer RK, Rainville P, Duncan GH, et al. Cortical representation of the sensory dimension of pain. J Neurophysiol. 2001;86: 402-411.
14. Marchand S, Bushnell MC, Duncan GH, et al. The effects of dorsal column stimulation on measures of clinical and experimental pain in man. Pain. 1991;45:249-257.
15. Charron J, Rainville P, Marchand S. Direct comparison of placebo effects on clinical and experimental pain. Clin J Pain. 2006;22: 204-211.
16. Devor M. Chronic pain in the aged: possible relation between neurogenesis, involution and pathophysiology in adult sensory ganglia. J Basic Clin Physiol Pharmacol. 1991;2:1-15.
17. Adler G, Nacimiento AC. Age-dependent changes of short-latency somatosensory evoked potentials in healthy adults. Appl Neurophysiol. 1988;51:55-59.
18. Martin DC, Rubin FH. Anatomy and physiology of the aging brain. In: Nussbaum PD, ed. The Handbook of Neuropsychology and Aging. New York: Plenum Press; 1997:32-43.
19. Pak-Woodruff DS. Normal aging and the brain. In: Pak-Woodruff DS, ed. The Neuropsychology of Aging. Oxford: BlackWell Publishers; 1997:86-108.
20. Talbot JD, Duncan GH, Bushnell MC, et al. Diffuse noxious inhibitory controls (DNICs): psychophysical evidence in man for intersegmental suppression of noxious heat perception by cold pressor pain. Pain. 1987;30:221-232.
21. Bingel U, Lorenz J, Schoell E, et al. Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network. Pain. 2006;120:8-15.
22. Matre D, Casey KL, Knardahl S. Placebo-induced changes in spinal cord pain processing. J Neurosci. 2006;26:559-563.
23. Petrovic P, Kalso E, Petersson KM, et al. Placebo and opioid analgesia - imaging a shared neuronal network. Science. 2002;295: 1737-1740.
24. Price DD, McGrath PA, Rafii A, et al. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain. Pain. 1983;17:45-56.