Cost-effectiveness analysis of two management strategies for dyspepsia

International Journal of Technology Assessment in Health Care

Volumn 23, Issue 3, 2007, Pages 376-384

  Kjeldsen, Hans C ^a   Bech, Mickael ^b   Christensen, Bo ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Antiulcer agents; Dyspepsia; Healthcare costs; Helicobacter pylori; Primary health care

Indexed keywords

ANTIULCER AGENTS; DYSPEPSIA; HEALTHCARE COSTS; HELICOBACTER PYLORI; PRIMARY HEALTH CARE;

COST EFFECTIVENESS; DISEASES; ECONOMIC ANALYSIS; HEALTH CARE; MEDICAL COMPUTING; PATIENT MONITORING;

ENDOSCOPY;

OMEPRAZOLE; PROTON PUMP INHIBITOR;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DYSPEPSIA; EMPIRICISM; ENDOSCOPIC THERAPY; ENDOSCOPY; FEMALE; GENERAL PRACTICE; GENERAL PRACTITIONER; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; OUTCOMES RESEARCH; PRIMARY MEDICAL CARE; PROSPECTIVE STUDY; RANDOMIZATION; REFLUX ESOPHAGITIS; SYMPTOM;

AGE FACTORS; COST-BENEFIT ANALYSIS; DYSPEPSIA; FEMALE; GASTROSCOPY; HUMANS; MALE; MIDDLE AGED; OMEPRAZOLE; PROSPECTIVE STUDIES; PROTON PUMPS; REPRODUCIBILITY OF RESULTS;

EID: 34250779835     PISSN: 02664623     EISSN: 14716348     Source Type: Journal    
DOI: 10.1017/S0266462307070420     Document Type: Article

References (42)

1. Agreus L, Borgquist L. The cost of gastro-oesophageal reflux disease, dyspepsia and peptic ulcer disease in Sweden. Pharmacoeconomics. 2002;20:347-355.
2. Bashford JN, Norwood J, Chapman SR. Why are patients prescribed proton pump inhibitors? Retrospective analysis of link between morbidity and prescribing in the General Practice Research Database. BMJ. 1998;317:452-456.
3. Bech M, Gyrd-Hansen D. Cost implications of routine mammography screening of women 50-69 years in the county of Funen, Denmark. Health Policy. 2000;54:125-141.
4. Briggs AH, Wonderling DE, Mooney CZ. Pulling cost-effectiveness analysis up by its bootstraps: A non-parametric approach to confidence interval estimation. Health Econ. 1997;6:327-340.
5. Bytzer P. Cost-effectiveness of gastroscopy. Ital J Gastroenterol Hepatol. 1999;31:749-760.
6. Bytzer P, Hansen JM, Schaffalizky De Muckadell OB. Empirical H2-blocker therapy on prompt endoscopy in management of dyspepsia. Lancet. 1994;343:811-816.
7. Bytzer P, Talley NJ. Dyspepsia. Ann Intern Med. 2001;134:815-822.
8. Delaney B, Ford A, Forman D, et al. Initial management strategies for dyspepsia. Cochrane Database Syst Rev. 2005;CD001961.
9. Delaney B, Moayyedi P, Deeks J, et al. The management of dyspepsia: A systematic review. Health Technol Assess. 2000;4:iii-189.
10. Delaney BC, Wilson S, Roalfe A, et al. Cost effectiveness of initial endoscopy for dyspepsia in patients over age 50 years: A randomised controlled trial in primary care. Lancet. 2000;356:1965-1969.
11. Ebell MH, Warbasse L, Brenner C. Evaluation of the dyspeptic patient: A cost-utility study. J Fam Pract. 1997;44:545-555.
12. El-Serag HB, Talley NJ. Systemic review: The prevalence and clinical course of functional dyspepsia. Aliment Pharmacol Ther. 2004;19:643-654.
13. Fendrick AM, Chernew ME, Hirth RA, et al. Alternative management strategies for patients with suspected peptic ulcer disease. Ann Intern Med. 1995;123:260-268.
14. Fenwick E, O'Brien BJ, Briggs A. Cost-effectiveness acceptability curves-facts, fallacies and frequently asked questions. Health Econ. 2004;13:405-415.
15. Garcia-Altes A, Jovell E. Economic analysis of treatment of functional dyspepsia. An assessment of the quality of published studies. Int J Technol Assess Health Care. 2001;17:517-527.
16. Gardner MJ, Altman DG. Estimation rather than hypothesis testing: Confidence intervals rather than P values. In: Gardner MJ, Altman DG, eds. Statistic with confidence. London: BMJ; 1989:6-19.
17. Gold MR, Siegel JE, Russell LB, et al. Cost-effectiveness in health and medicine. Oxford: Oxford University Press; 1996.
18. Heikkinen M, Pikkarainen P, Takala J, et al. General practitioners' approach to dyspepsia. Survey of consultation frequencies, treatment, and investigations. Scand J Gastroenterol. 1996;31:648-653.
19. Hirth RA, Bloom BS, Chernew ME, et al. Patient, physician, and payer perceptions and misperceptions of willingness to pay for diagnostic certainty. Int J Technol Assess Health Care. 2000;16:35-49.
20. Huang J, Lam SK, Malfertheiner P, et al. Has education about Helicobacter pylori infection been effective? Worldwide survey of primary care physicians. J Gastroenterol Hepatol. 2003;18:512-520.
21. Kjeldsen HC. Dyspepsia in general practice - Reasons to consult, management strategies and health economic consequences. Aarhus: Faculty of Health Science, University of Aarhus; 2005.
22. Kristiansen IS, Gyrd-Hansen D. Cost-effectiveness analysis based on the number-needed-to-treat: Common sense or non-sense? Health Econ. 2004;13:9-19.
23. Laheij RJ, Severens JL, Jansen JB, et al. Management in general practice of patients with persistent dyspepsia. A decision analysis. J Clin Gastroenterol. 1997;25:563-567.
24. Laheij RJ, Severens JL, Van de Lisdonk EH, et al. Randomized controlled trial of omeprazole or endoscopy in patients with persistent dyspepsia: A cost-effectiveness analysis. Aliment Pharmacol Ther. 1998;12:1249-1256.
25. Lassen AT, Hallas J, Schaffalitzky de Muckadell OB. Helicobacter pylori test and eradicate versus prompt endoscopy for management of dyspeptic patients: 6.7 year follow up of a randomised trial. Gut. 2004;53:1758-1763.
26. Lewin-Van Den Broek NT. Diagnostic and therapeutic strategies. Utrecht: University Utrecht; 1999.
27. Makris N, Barkun A, Crott R, et al. Cost-effectiveness of alternative approaches in the management of dyspepsia. Int J Technol Assess Health Care. 2003;19:446-464.
28. Mandelblatt JS, Fryback DG, Weinstein MC, et al. Assessing the effectiveness of health interventions for cost-effectiveness analysis. Panel on Cost-Effectiveness in Health and Medicine. J Gen Intern Med. 1997;12:551-558.
29. Martin RM, Lim AG, Kerry SM, et al. Trends in prescribing H2-receptor antagonists and proton pump inhibitors in primary care. Aliment Pharmacol Ther. 1998;12:797-805.
30. Nyren O, Lindberg G, Lindstrom E, et al. Economic costs of functional dyspepsia. Pharmacoeconomics. 1992;1:312-324.
31. Ofman JJ, Rabeneck L. The effectiveness of endoscopy in the management of dyspepsia: A qualitative systematic review. Am J Med. 1999;106:335-346.
32. Posnett J, Jan S. Indirect cost in economic evaluation: The opportunity cost of unpaid inputs. Health Econ. 1996;5: 13-23.
33. Schwartz LM, Woloshin S, Welch HG. Trends in diagnostic testing following a national guideline for evaluation of dyspepsia. Arch Intern Med. 1996;156:873-875.
34. Scott BB. Gastroenterology in the Trent Region in 1992 and a review of changes since 1975. Gut. 1995;36:468-472.
35. Sculpher M. The role and estimation of productivity costs in economic evaluation. In: Drummond M, McGuire A, eds. Economic evaluation in health care merging theory with practice. Oxford: Oxford University Press; 2001:94-112.
36. Severens JL, Laheij RJ, Jansen JB, et al. Estimating the cost of lost productivity in dyspepsia. Aliment Pharmacol Ther. 1998;12:919-923.
37. Silverstein MD, Petterson T, Talley NJ. Initial endoscopy or empirical therapy with or without testing for Helicobacter pylori for dyspepsia: A decision analysis. Gastroenterology. 1996;110:72-83.
38. Spiegel BM, Vakil NB, Ofman JJ. Dyspepsia management in primary care: A decision analysis of competing strategies. Gastroenterology. 2002;122:1270-1285.
39. Talley NJ, Colin-Jones DG, Koch KL, et al. Functional dyspepsia: A classification with guidelines for diagnosis and management. Gastroenterology. 1991:145-160.
40. Westbrook JI. Trends in the utilization of diagnostic upper GI endoscopy in New South Wales, Australia, 1988 to 1998. Gastrointest Endosc. 2002;55:847-853.
41. Westbrook JI, Duggan AE, McIntosh JH. Prescriptions for antiulcer drugs in Australia: Volume, trends, and costs. BMJ. 2001;323:1338-1339.
42. Westbrook JI, Rushworth RL, Rob MI, et al. Diagnostic procedures and health outcomes. Upper gastrointestinal tract investigations in the elderly. Med J Aust. 1993;159:242-245.