Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation

Biochemical Pharmacology

Volumn 74, Issue 3, 2007, Pages 504-510

  Itäaho, Katriina ^a   Alakurtti, Sami ^a   Yli Kauhaluoma, Jari ^a   Taskinen, Jyrki ^c   Coughtrie, Michael W H ^b   Kostiainen, Risto ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c NONE

Author keywords

Dopamine 3 O sulfate; Dopamine 4 O sulfate; Enzyme kinetics; HPLC; Regioselectivity; SULT1A3

Indexed keywords

ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; CARBON 13; DOPAMINE 3 SULFATE; DOPAMINE 4 SULFATE; HYDROGEN; HYDROXYL GROUP; SULFOTRANSFERASE; SULFOTRANSFERASE1A3; UNCLASSIFIED DRUG;

ARTICLE; BLOOD; CATALYSIS; CIRCULATION; CONCENTRATION (PARAMETERS); CRYSTAL STRUCTURE; DIODE; ELECTROCHEMICAL DETECTION; ENZYME KINETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; MASS SPECTROMETRY; MICHAELIS CONSTANT; NUCLEAR MAGNETIC RESONANCE; PRECIPITATION; PRIORITY JOURNAL; SULFONATION; SYNTHESIS; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM; SULFONES; SULFOTRANSFERASES;

EID: 34250777414     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.05.003     Document Type: Article

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