Dexamethasone treatment and ICAM-1 deficiency impair VEGF-induced angiogenesis in adult brain

Journal of Vascular Research

Volumn 44, Issue 4, 2007, Pages 283-291

  Kasselman, Lora J ^a,b   Kintner, Jennifer ^b   Sideris, Alexandra ^a   Pasnikowski, Elizabeth ^b   Krellman, Jason W ^a   Shah, Sagar ^a   Rudge, John S ^b   Yancopoulos, George D ^b   Wiegand, Stanley J ^b   Croll, Susan D ^a,b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

Angiogenesis; Brain; Dexamethasone; Enriched environments; Inflammation; Intercellular adhesion molecule 1

Indexed keywords

DEXAMETHASONE; INTERCELLULAR ADHESION MOLECULE 1; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN BLOOD VESSEL; BRAIN EDEMA; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENCEPHALITIS; FEMALE; HUMAN; HUMAN CELL; INFLAMMATION; MALE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

AGE FACTORS; ANIMALS; BRAIN; CELLS, CULTURED; CEREBROVASCULAR CIRCULATION; DEXAMETHASONE; ENDOTHELIAL CELLS; GLUCOCORTICOIDS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MICE; MICE, KNOCKOUT; NEOVASCULARIZATION, PATHOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34250754840     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000101450     Document Type: Article

References (28)

1. Rosenstein JM, Mani N, Silverman WF, Krum JM: Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo. Proc Natl Acad Sci 1998;95:7086-7091.
2. Croll SD, Ransohoff RM, Cai N, Zhang Q, Martin FJ, Wei T, Kasselman LJ, Kintner J, Murphy A, Yancopoulos GD, Wiegand SJ: VEGF-mediated inflammation precedes angiogenesis in adult brain. Exp Neurol 2004; 187:388-402.
3. Senger DR, Perruzzi CA, Feder J, Dvorak HF: A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res 1986;46: 5629-5632.
4. Proescholdt MA, Heiss JD, Walbridge S, Muhlhauser J, Capogrossi MC, Oldfield EH, Merrill MJ: Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brain. J Neuropathol Exp Neurol 1999;586:613-627.
5. Shoshani Y, Pe'er J, Doviner V, Frucht-Pery J, Solomon A: Increased expression of inflammatory cytokines and matrix metalloproteinases in pseudophakic corneal edema. Invest Ophthalmol Vis Sci 2005;46:1940-1947.
6. Mor F, Quintana FJ, Cohen IR: Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization. J Immunol 2004;172:4618-4623.
7. Dvorak HF, Nagy JA, Feng D, Brown LF, Dvorak AM: Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis. Curr Topics Microbiol Immunol 1999;237:97-132.
8. Pipp F, Heil M, Issbrucker K, Ziegelhoeffer T, Martin S, van den Heuvel J, Weich H, Fernandez B, Golomb G, Carmeliet P, Schaper W, et al: VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism. Circ Res 2003;92:378-385.
9. Watson RE, Wiegand SJ, Clough RW, Hoffman GE: Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides 1986;7:155-159.
10. Morse JK, Wiegand SJ, Anderson K, You Y, Cai N, Carnahan J, Miller J, DiStefano PS, Altar CA, Lindsay RM, et al: Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection. J Neurosci 1993;13:4146-4156.
11. Ferrara N, Gerber HP, LeCouter J: The biology of VEGF and its receptors. Nat Med 2003;9:669-676.
12. Ishiko O, Sumi T, Yoshida H, Hyun Y, Ogita S: Angiogenesis in the adipose tissue of tumor-bearing rabbits treated by cyclic plasma perfusion. Int J Oncol 2001;19:785-790.
13. Argandona EG, Bengoetxea H, Lafuente JV: Lack of experience-mediated differences in the immunohistochemical expression of blood-brain barrier markers (EBA and GluT-1) during the postnatal development of the rat visual cortex. Brain Res Dev Brain Res 2005;156:158-166.
14. Thompson HJ, McGinley JN, Spoelstra NS, Jiang W, Zhu Z, Wolfe P: Effect of dietary energy restriction on vascular density during mammary carcinogenesis. Cancer Res 2004;64:5643-5650.
15. Mamputu JC, Renier G: Advanced glycation end-products increase monocyte adhesion to retinal endothelial cells through vascular endothelial growth factor-induced ICAM-1 expression: inhibitory effect of antioxidants. J Leukoc Biol 2004;75:1062-1069.
16. Radisavljevic Z, Avraham H, Avraham S: Vascular endothelial growth factor up-regulates ICAM-1 expression via the phosphatidylinositol 3 OH-kinase/AKT/Nitric oxide pathway and modulates migration of brain microvascular endothelial cells. J Biol Chem 2000;275:20770-20774.
17. Kevil CG, Pruitt J, Kavanagh TJ, Wilkerson J, Farin F, Moellering D, Darley-Usmar VM, Bullard DC, Patel RP: Regulation of endothelial glutathione by ICAM-1: implications for inflammation. FASEB J 2004;18:1321-1323.
18. Langston W, Chidlow JH Jr, Booth BA, Barlow SC, Lefer DJ, Patel RP, Kevil CG: Regulation of endothelial glutathione by ICAM-1 governs VEGF-A-mediated eNOS activity and angiogenesis. Free Radic Biol Med 2007; 42:720-729.
19. Schmidt AJ, Krieg J-C, Vedder H: Differential effects of glucocorticoids and gonadal steroids on glutathione levels in neuronal and glial cell systems. J Neurosci Res 2002; 67:544-550.
20. Rahman I: Regulation of nuclear factor-κB, activator protein-1, and glutathione levels by tumor necrosis factor-α and dexamethasone in alveolar epithelial cells. Biochem Pharmacol 2000;60:1041-1049.
21. Pakala R, Watanabe T, Benedict CR: Induction of endothelial cell proliferation by angiogenic factors released by activated monocytes. Cardiovasc Radiat Med 2002;3:95-101.
22. Arras M, Ito WD, Scholz D, Winkler B, Schaper J, Schaper W: Monocyte activation in angiogenesis and collateral growth in the rabbit hindlimb. J Clin Invest 1998;101:40-50.
23. Schaper W, Buschmann I: Arteriogenesis, the good and bad of it. Cardiovasc Res 1999; 43:835-837.
24. Scholz D, Ito W, Fleming I, Deindl E, Sauer A, Wiesnet M, Busse R, Schaper J, Schaper W: Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis). Virchows Arch 2000;436: 257-270.
25. Moldovan NI, Goldschmidt-Clermont PJ, Parker-Thornburg J, Shapiro SD, Kolattukudy PE: Contribution of monocytes/macrophages to compensatory neovascularization: the drilling of metalloelastase-positive tunnels in ischemic myocardium. Circ Res 2000; 87:378-384.
26. Fernandez Pujol B, Lucibello FC, Gehling UM, Lindemann K, Weidner N, Zuzarte ML, Adamkiewicz J, Elsasser HP, Muller R, Havemann K: Endothelial-like cells derived from human CD14 positive monocytes. Differentiation 2000;65:287-300.
27. Shi Q, Rafii S, Wu MH, Wijelath ES, Yu C, Ishida A, Fujita Y, Kothari S, Mohle R, Sauvage LR, et al: Evidence for circulating bone marrow-derived endothelial cells. Blood 1998;92:362-367.
28. Ishida S, Usui T, Yamashiro K, Kaji Y, Amano S, Ogura Y, Hida T, Oguchi Y, Ambati J, Miller JW, et al: VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med 2003;198:483-489.