MR Imaging Evaluation of the Bone Marrow and Marrow Infiltrative Disorders of the Lumbar Spine

Magnetic Resonance Imaging Clinics of North America

Volumn 15, Issue 2, 2007, Pages 199-219

  Alyas, Faisal ^a   Saifuddin, Asif ^a   Connell, David ^a  

^a ROYAL NATIONAL ORTHOPAEDIC HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORAMPHENICOL; FLUORODEOXYGLUCOSE F 18; GADOLINIUM; GOLD; GRANULOCYTE COLONY STIMULATING FACTOR; HEMOSIDERIN; IMMUNOSUPPRESSIVE AGENT; IRON OXIDE; PHENYLBUTAZONE; STEROID;

AMYLOIDOSIS; APLASTIC ANEMIA; BONE MARROW; BONE MARROW DEPRESSION; BONE MARROW DISEASE; BONE MARROW TRANSPLANTATION; CANCER DIAGNOSIS; CELL PROLIFERATION; CONTRAST ENHANCEMENT; DIFFUSION WEIGHTED IMAGING; GAUCHER DISEASE; HUMAN; IMAGE ANALYSIS; IMAGING SYSTEM; LEUKEMIA; LIPID STORAGE; LUMBAR SPINE; LUMBAR VERTEBRA; LYMPHOMA; LYSOSOME STORAGE DISEASE; METASTASIS; MULTIPLE MYELOMA; MYELODYSPLASTIC SYNDROME; MYELOFIBROSIS; MYELOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYCYTHEMIA VERA; POSITRON EMISSION TOMOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; REVIEW; SEX DIFFERENCE; SPINAL CORD; SYSTEMIC MASTOCYTOSIS; TRABECULAR BONE; WALDENSTROEM MACROGLOBULINEMIA;

BONE MARROW; BONE MARROW DISEASES; CONTRAST MEDIA; DIAGNOSIS, DIFFERENTIAL; HUMANS; LUMBAR VERTEBRAE; MAGNETIC RESONANCE IMAGING; SPINAL DISEASES;

EID: 34250749260     PISSN: 10649689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mric.2007.03.002     Document Type: Review

References (130)

1. Vogler III J.B., and Murphy W.A. Bone marrow imaging. Radiology 168 3 (1988) 679-693
2. Pettersson H, Gillespy 1, Hamlin DJ, et al. Primary musculoskeletal tumors: examination with MR imaging compared with conventional modalities. Radiology 1987;164(1):237-41.
3. Moulopoulos L.A., Varma D.G., Dimopoulos M.A., et al. Multiple myeloma: spinal MR imaging in patients with untreated newly diagnosed disease. Radiology 185 3 (1992) 833-840
4. Smith S.R., Williams C.E., Davies J.M., et al. Bone marrow disorders: characterization with quantitative MR imaging. Radiology 172 3 (1989) 805-810
5. Zimmer W.D., Berquist T.H., McLeod R.A., et al. Bone tumors: magnetic resonance imaging versus computed tomography. Radiology 155 3 (1985) 709-718
6. Avrahami E., Tadmor R., Dally O., et al. Early MR demonstration of spinal metastases in patients with normal radiographs and CT and radionuclide bone scans. J Comput Assist Tomogr 13 4 (1989) 598-602
7. Sugimura K., Yamasaki K., Hajime K., et al. Bone marrow diseases of the spine: differentiation with T1 and T2 relaxation times in MR imaging. Radiology 165 2 (1987) 541-554
8. Vanel D., Dromain C., and Tardivon A. MRI of bone marrow disorders. Eur Radiol 10 2 (2000) 224-229
9. Nobauer I., and Uffmann M. Differential diagnosis of focal and diffuse neoplastic diseases of bone marrow in MRI. Eur J Radiol 55 1 (2005) 2-32
10. Steiner R.M., Mitchell D.G., Rao V.M., et al. Magnetic resonance imaging of diffuse bone marrow disease. Radiol Clin North Am 31 2 (1993) 383-409
11. Vande Berg B.C., Lecouvet F.E., Michaux L., et al. Magnetic resonance imaging of the bone marrow in hematological malignancies. Eur Radiol 8 8 (1998) 1335-1344
12. Herneth A.M., Friedrich K., Weidekamm C., et al. Diffusion weighted imaging of bone marrow pathologies. Eur J Radiol 55 1 (2005) 74-83
13. Ghanem N., Altehoefer C., Hogerle S., et al. Comparative diagnostic value and therapeutic relevance of magnetic resonance imaging and bone marrow scintigraphy in patients with metastatic solid tumors of the axial skeleton. Eur J Radiol 43 3 (2002) 256-261
14. Flickinger F.W., and Sanal S.M. Bone marrow MRI: techniques and accuracy for detecting breast cancer metastases. Magn Reson Imaging 12 6 (1994) 829-835
15. Yao L., and Seeger L.L. MR effective at detecting pathology of marrow space. Diagn Imaging 13 7 (1991) 116-120
16. Depaoli L., Davini O., Foggetti M.D., et al. Evaluation of bone marrow cellularity by magnetic resonance imaging in patients with myelodysplastic syndrome. Eur J Haematol 49 2 (1992) 105-107
17. Vande Berg B.C., Malghem J., Lecouvet F.E., et al. Magnetic resonance imaging of normal bone marrow. Eur Radiol 8 8 (1998) 1327-1334
18. Snyder W.S., Cook M.J., Nasset E.S., et al. Report of the task group on reference man. In: ICRP (Ed). International commission on radiological protection (1975), Pergamon Press, Oxford (UK) 85-98
19. Mahnken A.H., Wildberger J.E., Adam G., et al. Is there a need for contrast-enhanced T1-weighted MRI of the spine after inconspicuous short tau inversion recovery imaging?. Eur Radiol 15 7 (2005) 1387-1392
20. Simon J.H., and Szumowski J. Chemical shift imaging with paramagnetic contrast material enhancement for improved lesion depiction. Radiology 171 2 (1989) 539-543
21. Mirowitz S.A., Apicella P., Reinus W.R., et al. MR imaging of bone marrow lesions: relative conspicuousness on T1-weighted, fat-suppressed T2-weighted, and STIR images. Am J Roentgenol 162 1 (1994) 215-221
22. Mirowitz S.A. Fast scanning and fat-suppression MR imaging of musculoskeletal disorders. Am J Roentgenol 161 6 (1993) 1147-1157
23. Vanel D., Bittoun J., and Tardivon A. MRI of bone metastases. Eur Radiol 8 8 (1998) 1345-1351
24. Zajick Jr. D.C., Morrison W.B., Schweitzer M.E., et al. Benign and malignant processes: normal values and differentiation with chemical shift MR imaging in vertebral marrow. Radiology 237 2 (2005) 590-596
25. Seiderer M., Staebler A., and Wagner H. MRI of bone marrow: opposed-phase gradient-echo sequences with long repetition time. Eur Radiol 9 4 (1999) 652-661
26. Erly W.K., Oh E.S., and Outwater E.K. The utility of in-phase/opposed-phase imaging in differentiating malignancy from acute benign compression fractures of the spine. AJNR Am J Neuroradiol 27 6 (2006) 1183-1188
27. Baur A., Stabler A., Bruning R., et al. Diffusion-weighted MR imaging of bone marrow: differentiation of benign versus pathologic compression fractures. Radiology 207 2 (1998) 349-356
28. Spuentrup E., Buecker A., Adam G., et al. Diffusion-weighted MR imaging for differentiation of benign fracture edema and tumor infiltration of the vertebral body. Am J Roentgenol 176 2 (2001) 351-358
29. Baur A., Dietrich O., and Reiser M. Diffusion-weighted imaging of bone marrow: current status. Eur Radiol 13 7 (2003) 1699-1708
30. Saifuddin A., Bann K., Ridgaway J.P., et al. Bone marrow blood supply in gadolinium-enhanced magnetic resonance imaging. Skeletal Radiol 23 6 (1994) 455-457
31. Griffith J.F., Yeung D.K., Antonio G.E., et al. Vertebral bone mineral density, marrow perfusion, and fat content in healthy men and men with osteoporosis: dynamic contrast-enhanced MR imaging and MR spectroscopy. Radiology 236 3 (2005) 945-951
32. Montazel J.L., Divine M., Lepage E., et al. Normal spinal bone marrow in adults: dynamic gadolinium-enhanced MR imaging. Radiology 229 3 (2003) 703-709
33. Sze G., Bravo S., Baierl P., et al. Developing spinal column: gadolinium-enhanced MR imaging. Radiology 180 2 (1991) 497-502
34. Rahmouni A., Montazel J.L., Divine M., et al. Bone marrow with diffuse tumor infiltration in patients with lymphoproliferative diseases: dynamic gadolinium-enhanced MR imaging. Radiology 229 3 (2003) 710-717
35. Daldrup-Link H.E., Rummeny E.J., Ihssen B., et al. Iron-oxide-enhanced MR imaging of bone marrow in patients with non-Hodgkin's lymphoma: differentiation between tumor infiltration and hypercellular bone marrow. Eur Radiol 12 6 (2002) 1557-1566
36. Vande Berg B.C., Lecouvet F.E., Galant C., et al. Normal variants and frequent marrow alterations that simulate bone marrow lesions at MR imaging. Radiol Clin North Am 43 4 (2005) 761-770
37. Ishijima H., Ishizaka H., Horikoshi H., et al. Water fraction of lumbar vertebral bone marrow estimated from chemical shift misregistration on MR imaging: normal variations with age and sex. Am J Roentgenol 167 2 (1996) 355-358
38. Dunnill M.S., Anderson J.A., and Whitehead R. Quantitative histological studies on age changes in bone. J Pathol Bacteriol 94 2 (1967) 275-291
39. Schellinger D., Lin C.S., Hatipoglu H.G., et al. Potential value of vertebral proton MR spectroscopy in determining bone weakness. Am J Neuroradiol 22 8 (2001) 1620-1627
40. Justesen J., Stenderup K., Ebbesen E.N., et al. Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2 3 (2001) 165-171
41. Ricci C., Cova M., Kang Y.S., et al. Normal age-related patterns of cellular and fatty bone marrow distribution in the axial skeleton: MR imaging study. Radiology 177 1 (1990) 83-88
42. Modic M.T., Masaryk T.J., Ross J.S., et al. Imaging of degenerative disk disease. Radiology 168 1 (1988) 177-186
43. Hajek P.C., Baker L.L., Goobar J.E., et al. Focal fat deposition in axial bone marrow: MR characteristics. Radiology 162 1 Pt 1 (1987) 245-249
44. Schweitzer M.E., Levine C., Mitchell D.G., et al. Bull's-eyes and halos: useful MR discriminators of osseous metastases. Radiology 188 1 (1993) 249-252
45. Levine C.D., Schweitzer M.E., and Ehrlich S.M. Pelvic marrow in adults. Skeletal Radiol 23 5 (1994) 343-347
46. Bordalo-Rodrigues M., Galant C., Lonneux M., et al. Focal nodular hyperplasia of the hematopoietic marrow simulating vertebral metastasis on FDG positron emission tomography. Am J Roentgenol 180 3 (2003) 669-671
47. Deutsch A.L., Mink J.H., Rosenfelt F.P., et al. Incidental detection of hematopoietic hyperplasia on routine knee MR imaging. Am J Roentgenol 152 2 (1989) 333-336
48. Stabler A., Doma A.B., Baur A., et al. Reactive bone marrow changes in infectious spondylitis: quantitative assessment with MR imaging. Radiology 217 3 (2000) 863-868
49. Fletcher B.D., Wall J.E., and Hanna S.L. Effect of hematopoietic growth factors on MR images of bone marrow in children undergoing chemotherapy. Radiology 189 3 (1993) 745-751
50. Durie B.G., Kyle R.A., Belch A., et al. Scientific advisors of the International Myeloma Foundation. Myeloma management guidelines: a consensus report from the scientific advisors of the International Myeloma Foundation. Hematol J 4 6 (2003) 379-398
51. Kyle R.A., Therneau T.M., Rajkumar S.V., et al. A long term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med 346 (2002) 564-569
52. Bellaiche L., Laredo J.D., Liote F., et al. Magnetic resonance appearance of monoclonal gammopathies of unknown significance and multiple myeloma. Spine 22 (1997) 2551-2557
53. Mariette X., Zagdanski A.M., Guermazi A., et al. Prognostic value of vertebral lesions detected by magnetic resonance imaging in patients with stage I multiple myeloma. Br J Haematol 104 4 (1999) 723-729
54. Vande Berg B.C., Lecouvet F.E., Michaux L., et al. Stage I multiple myeloma: value of MR imaging of the bone marrow in the determination of prognosis. Radiology 201 1 (1996) 243-246
55. Baur-Melnyk A., Buhmann S., Durr H.R., et al. Role of MRI for the diagnosis and prognosis of multiple myeloma. Eur J Radiol 55 1 (2005) 56-63
56. Lecouvet F.E., Vande Berg B.C., Michaux L., et al. Stage III multiple myeloma: clinical and prognostic value of spinal bone marrow MR imaging. Radiology 209 3 (1998) 653-660
57. Stabler A., Baur A., Bartl R., et al. Contrast enhancement and quantitative signal analysis in MR imaging of multiple myeloma: assessment of focal and diffuse growth patterns in marrow correlated with biopsies and survival rates. Am J Roentgenol 167 4 (1996) 1029-1036
58. Rahmouni A., Divine M., Mathieu D., et al. Detection of multiple myeloma involving the spine: efficacy of fat-suppression and contrast-enhanced MR imaging. Am J Roentgenol 160 5 (1993) 1049-1052
59. Baur A., Stabler A., Bartl R., et al. MRI gadolinium enhancement of bone marrow: age-related changes in normals and in diffuse neoplastic infiltration. Skeletal Radiol 26 7 (1997) 414-418
60. Moulopoulos L.A., and Dimopoulos M.A. Magnetic resonance imaging of the bone marrow in hematologic malignancies. Blood 90 6 (1997) 2127-2147
61. Baur A., Bartl R., Pellengahr C., et al. Neovascularization of bone marrow in patients with diffuse multiple myeloma: a correlative study of magnetic resonance imaging and histopathologic findings. Cancer 101 11 (2004) 2599-2604
62. Libshitz H.I., Malthouse S.R., Cunningham D., et al. Multiple myeloma: appearance at MR imaging. Radiology 182 3 (1992) 833-837
63. Moulopoulos L.A., Dimopoulos M.A., Smith T.L., et al. Prognostic significance of magnetic resonance imaging in patients with asymptomatic multiple myeloma. J Clin Oncol 13 1 (1995) 251-256
64. Baur A., Stabler A., Nagel D., et al. Magnetic resonance imaging as a supplement for the clinical staging system of Durie and Salmon?. Cancer 95 6 (2002) 1334-1345
65. Moulopoulos L.A., Dimopoulos M.A., Alexanian R., et al. Multiple myeloma: MR patterns of response to treatment. Radiology 193 2 (1994) 441-446
66. Duhem, Ries F., and Dicato M. Accuracy of magnetic resonance imaging (MRI) of bone marrow in Waldenstrom's macroglobulinemia. Blood 84 (1994) 653
67. Moulopoulos L.A., Dimopoulos M.A., Varma D.G.K., et al. Waldenstrom macroglobulinemia: MR imaging of the spine and CT of the abdomen and pelvis. Radiology 188 3 (1993) 669-673
68. Gean-Marton A.D., Kirsch C.F., Vezina L.G., et al. Focal amyloidosis of the head and neck: evaluation with CT and MR imaging. Radiology 181 2 (1991) 521-525
69. Ito M., Abumi K., Takeda N., et al. Pathologic features of spinal disorders in patients treated with long-term hemodialysis. Spine 23 19 (1998) 2127-2133
70. Campistol J.M., and Skinner M. Beta-2 microglobulin amyloidosis: an overview. Semin Dial 6 (1993) 117-126
71. Faure C., Venin B., Bousquet J.C., et al. Primary amyloidosis of bones. MRI aspects. J Radiol 76 11 (1995) 1025-1027
72. Olliff J.F., Hardy J.R., Williams M.P., et al. Magnetic resonance imaging of spinal amyloid. Clin Radiol 40 6 (1989) 632-633
73. Jensen K.E., Sorensen P.G., Thomsen C., et al. Prolonged T1 relaxation of the hemopoietic bone marrow in patients with chronic leukemia. Acta Radiol 31 5 (1990) 445-448
74. Lecouvet F.E., Vande Berg B.C., Michaux L., et al. Early chronic lymphocytic leukemia: prognostic value of quantitative bone marrow MR imaging findings and correlation with hematologic variables. Radiology 204 3 (1997) 813-818
75. Lecouvet F.E., Vande Berg B.C., Michaux L., et al. Chronic lymphocytic leukemia: changes in bone marrow composition and distribution assessed with quantitative MRI. J Magn Reson Imaging 8 3 (1998) 733-739
76. Bongers H., Schick F., Skalej M., et al. Localized in vivo 1H spectroscopy and chemical shift imaging of the bone marrow in leukemic patients. Eur Radiol 4 2 (1992) 350-356
77. Gerard E.L., Ferry J.A., Amrein P.C., et al. Compositional changes in vertebral bone marrow during treatment for acute leukemia: assessment with quantitative chemical shift imaging. Radiology 183 1 (1992) 39-46
78. Schick F., Einsele H., Lutz O., et al. Lipid selective MR imaging and localized 1H spectroscopy of bone marrow during therapy of leukemia. Anticancer Res 16 3B (1996) 1545-1551
79. Vande Berg B.C., Schmitz P.J., Scheiff J.M., et al. Acute myeloid leukemia: lack of predictive value of sequential quantitative MR imaging during treatment. Radiology 197 1 (1995) 301-305
80. Jensen K.E., Grundtvig Sorensen P., Thomsen C., et al. Magnetic resonance imaging of the bone marrow in patients with acute leukemia during and after chemotherapy. Changes in T1 relaxation. Acta Radiol 31 4 (1990) 361-369
81. Vande Berg B.C., Michaux L., Scheiff J.M., et al. Sequential quantitative MR analysis of bone marrow: differences during treatment of lymphoid versus myeloid leukemia. Radiology 201 2 (1996) 519-523
82. Pui M.H., Fletcher B.D., and Langston J.W. Granulocytic sarcoma in childhood leukemia: imaging features. Radiology 190 3 (1994) 698-702
83. Moulopoulos L.A., Maris T.G., Papanikolaou N., et al. Detection of malignant bone marrow involvement with dynamic contrast-enhanced magnetic resonance imaging. Ann Oncol 14 1 (2003) 152-158
84. Kaplan K.R., Mitchell D.G., Steiner R.M., et al. Polycythemia vera and myelofibrosis: correlation of MR imaging, clinical, and laboratory findings. Radiology 183 2 (1992) 329-334
85. Padhani A., and Husband J. Bone. In: Husband J.E.S., and Reznek R.H. (Eds). Imaging in oncology (1998), Isis Medical Media, Oxford (UK) 765-786
86. Algra P.R., Bloem J.L., Tissing H., et al. Detection of vertebral metastases: comparison between MR imaging and bone scintigraphy. Radiographics 11 2 (1991) 219-232
87. Colman L.K., Porter B.A., Redmond III J., et al. Early diagnosis of spinal metastases by CT and MR studies. J Comput Assist Tomogr 12 3 (1988) 423-426
88. Kattapuram S.V., Khurana J.S., Scott J.A., et al. Negative scintigraphy with positive magnetic resonance imaging in bone metastases. Skeletal Radiol 19 2 (1990) 113-116
89. Kim H.J., Ryu K.N., Choi W.S., et al. Spinal involvement of hematopoietic malignancies and metastasis: differentiation using MR imaging. Clin Imaging 23 2 (1999) 125-133
90. Baker L.L., Goodman S.B., Perkash I., et al. Benign versus pathologic compression fractures of vertebral bodies: assessment with conventional spin-echo, chemical shift, and STIR MR imaging. Radiology 174 2 (1990) 495-502
91. Resnick D., and Niwayama G. Osteoporosis. In: Resnick D. (Ed). Diagnosis of bone and joint disorders. 3rd edition (1995), WB Saunders, Philadephia 1837-1839
92. Yuh W.T., Zachar C.K., Barloon T.J., et al. Vertebral compression fractures: distinction between benign and malignant causes with MR imaging. Radiology 172 1 (1989) 215-218
93. Baur A., Stabler A., Arbogast S., et al. Acute osteoporotic and neoplastic vertebral compression fractures: fluid sign at MR imaging. Radiology 225 3 (2002) 730-735
94. Lo L.D., Schweitzer M.E., Juneja V., et al. Are L5 fractures an indicator of metastasis?. Skeletal Radiol 29 8 (2000) 454-458
95. Baur A., Huber A., Ertl-Wagner B., et al. Diagnostic value of increased diffusion weighting of a steady-state free precession sequence for differentiating acute benign osteoporotic fractures from pathologic vertebral compression fractures. Am J Neuroradiol 22 2 (2001) 366-372
96. Baur A., Huber A., Durr H.R., et al. Differentiation of benign osteoporotic and neoplastic vertebral compression fractures with a diffusion-weighted, steady-state free precession sequence. Rofo 174 1 (2002) 70-75
97. Pond G.D., Castellino R.A., Horning S., et al. Non-Hodgkin lymphoma: influence of lymphography, CT, and bone marrow biopsy on staging and management. Radiology 170 1 Pt 1 (1989) 159-164
98. Howell S.J., Grey M., Chang J., et al. The value of bone marrow examination in the staging of Hodgkin's lymphoma: a review of 955 cases seen in a regional cancer centre. Br J Haematol 119 2 (2002) 408-411
99. Linden A., Zankovich R., Theissen P., et al. Malignant lymphoma: bone marrow imaging versus biopsy. Radiology 173 2 (1989) 335-339
100. Vourtsi A.D., Moulopoulos L.A., Gouliamos A., et al. The "wrap-around" MR sign: a telltale sign of lymphoma of the bone marrow. Eur Radiol 7 (1997) S390
101. Varan A., Cila A., and Buyukpamukcu M. Prognostic importance of magnetic resonance imaging in bone marrow involvement of Hodgkin disease. Med Pediatr Oncol 32 4 (1999) 267-271
102. Tardivon A.A., Munck J.N., Shapeero L.G., et al. Can clinical data help to screen patients with lymphoma for MR imaging of bone marrow?. Ann Oncol 6 8 (1995) 795-800
103. Smith R., Schilder K., Shaer A., et al. Lymphoma staging with bone marrow MRI. Proc Am Soc Clin Oncol 14 (1995) 390
104. Kusumoto S., Jinnai I., Matsuda A., et al. Bone marrow patterns in patients with aplastic anaemia and myelodysplastic syndrome: observations with magnetic resonance imaging. Eur J Haematol 59 3 (1997) 155-161
105. Katsuya T., Inoue T., Ishizaka H., et al. Dynamic contrast-enhanced MR imaging of the water fraction of normal bone marrow and diffuse bone marrow disease. Radiat Med 18 5 (2000) 291-297
106. Negendank W., Weissman D., Bey T.M., et al. Evidence for clonal disease by magnetic resonance imaging in patients with hypoplastic marrow disorders. Blood 78 11 (1991) 2872-2879
107. Bayik M., Kodalli N., Gürmen N., et al. Magnetic resonance imaging in myelofibrosis. Blood 92 8 (1998) 2995-2997
108. Roca M., Mota J., Giraldo P., et al. Systemic mastocytosis: MRI of bone marrow involvement. Eur Radiol 9 6 (1999) 1094-1097
109. Hauswirth A.W., Simonitsch-Klupp I., Uffmann M., et al. Response to therapy with interferon alpha-2b and prednisolone in aggressive systemic mastocytosis: report of five cases and review of the literature. Leuk Res 28 3 (2004) 249-257
110. Avila N.A., Ling A., Metcalfe D.D., et al. Mastocytosis: magnetic resonance imaging patterns of marrow disease. Skeletal Radiol 27 3 (1998) 119-126
111. Resnick D., and Haghighi P. Myeloproliferative disorders. In: Resnick D. (Ed). Diagnosis of bone and joint disorders. 3rd edition. (vol. 4) (1995), WB Saunders, Philadelphia 2483-2487
112. Ho L.M., and Lipper M.H. Mastocytosis of the axial skeleton presenting as an epidural mass lesion: MR imaging appearance. Am J Roentgenol 167 3 (1996) 716-718
113. Haney K., Russell W., Raila F.A., et al. MRI characteristics of systemic mastocytosis of the lumbosacral spine. Skeletal Radiol 25 2 (1996) 171-173
114. Levin T.L., Sheth S.S., Hurlet A., et al. MR marrow signs of iron overload in transfusion-dependent patients with sickle cell disease. Pediatr Radiol 25 8 (1995) 614-619
115. Charrow J., Esplin J.A., Gribble T.J., et al. Gaucher disease: recommendations on diagnosis, evaluation, and monitoring. Arch Intern Med 158 16 (1998) 1754-1760
116. Rosenthal D.I., Scott J.A., Barranger J., et al. Evaluation of Gaucher disease using magnetic resonance imaging. J Bone Joint Surg Am 68 6 (1986) 802-808
117. Hermann G., Shapiro R.S., Fikry Abdelwahab I., et al. MR imaging in adults with Gaucher disease type 1: evaluation of marrow involvement and disease activity. Skeletal Radiol 22 4 (1993) 247-251
118. Maas M., van Kuijk C., Stoker J., et al. Quantification of bone involvement in Gaucher disease: MR imaging bone marrow burden score as an alternative to Dixon quantitative chemical shift MR imaging-initial experience. Radiology 229 2 (2003) 554-561
119. Stevens S.K., Moore S.G., and Kaplan I.D. Early and late bone-marrow changes after irradiation: MR evaluation. Am J Roentgenol 154 4 (1990) 745-750
120. Mitchell M.J., and Logan P.M. Radiation-induced changes in bone. Radiographics 18 5 (1998) 1125-1136
121. Yankelevitz D.F., Henschke C.I., Knapp P.H., et al. Effect of radiation therapy on thoracic and lumbar bone marrow: evaluation with MR imaging. Am J Roentgenol 157 1 (1991) 87-92
122. Otake S., Mayr N.A., Ueda T., et al. Radiation-induced changes in MR signal intensity and contrast enhancement of lumbosacral vertebrae: do changes occur only inside the radiation therapy field?. Radiology 222 1 (2002) 179-183
123. Sacks E.L., Goris M.L., Glatstein E., et al. Bone marrow regeneration following large field radiation. Cancer 42 3 (1978) 1057-1065
124. Lieschke G.J., and Burgess A.W. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. N Engl J Med 327 1 (1992) 28-35
125. Ciray I., Lindman H., Astrom G.K., et al. Effect of granulocyte colony-stimulating factor (G-CSF)-supported chemotherapy on MR imaging of normal red bone marrow in breast cancer patients with focal bone metastases. Acta Radiol 44 5 (2003) 472-484
126. Hartman R.P., Sundaram M., Okuno S.H., et al. Effect of granulocyte-stimulating factors on marrow of adult patients with musculoskeletal malignancies: incidence and MRI findings. Am J Roentgenol 183 3 (2004) 645-653
127. Altehoefer C., Bertz H., Ghanem N.A., et al. Extent and time course of morphological changes of bone marrow induced by granulocyte-colony stimulating factor as assessed by magnetic resonance imaging of healthy blood stem cell donors. J Magn Reson Imaging 14 2 (2001) 141-146
128. Stevens S.K., Moore S.G., and Amylon M.D. Repopulation of the marrow after transplantation: MR imaging with pathologic correlation. Radiology 175 1 (1990) 213-218
129. Tanner S.F., Clarke J., Leach M.O., et al. MRI in the evaluation of late bone marrow changes following bone marrow transplantation. Br J Radiol 69 828 (1996) 1145-1151
130. Pereira P.L., Schick F., Einsele H., et al. MR tomography of the bone marrow changes after high-dosage chemotherapy and autologous peripheral stem-cell transplantation. Rofo 170 3 (1999) 251-257