Analysis of C46T gene polymorphism of FXII in patients with venous thrombosis patients

Journal of Jilin University Medicine Edition

Volumn 33, Issue 3, 2007, Pages 555-558

  Zhang, Gui Rong ^a   Yu, Yan Hui ^a   Chen, Guang ^a   Wu, Shan Li ^a   Qu, Cheng Gang ^a   Zhao, Wen Guang ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Factor XII; Polymorphism (genetics); Venous thrombosis

Indexed keywords

BLOOD CLOTTING FACTOR 12;

ADULT; AGED; ALLELE; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DNA POLYMORPHISM; EXON; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; VEIN THROMBOSIS;

EID: 34250743011     PISSN: 1671587X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Lane DA, Grant PJ. Role of hemostatic gene polymorphism in venous and arterial thrombotic disedse [J]. Blood, 2000, 95 (5): 1517-1532.
2. Meissner MH, Strandness DE. Pathophysiology and natural history of acute deep venous thrombosis [A]. In: Rutherford HB. Vascular Surgery [M]. 5th ed. Philadelphia: Saunders Company, 2000: 1929-1930.
3. Kanaji T, Okamura T, Osaki K, et al. A common genetic polymorphism (46 C to T substitution) in the 5′-untranslated region of the coagulation factor XII gene is associated with low transition efficiency and decrease in plasma F XII level [J]. Blood, 1998, 91 (6): 2010-2014.
4. Soria JM, Almasy L, Souto JC. A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease [J]. Am J Hum Genet, 2002, 70 (3): 567-574.
5. Tirado I, Soria JM, Mateo J, et al. Association after linkage analysis indicates that homozygosity for the 46C→T polymorphism in the F12 gene is a genetic risk factor for venous thrombosis [J]. Thromb Haemost, 2004, 91 (5): 899-904.
6. Zito F, Lowe GDO, Rumley A, et al. Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study [J]. Atherosclerosis, 2002, 165 (1): 153-158.
7. Soria JM, Almasy L, Souto JC, et al. Linkage analysis demonstrates that the prothrombin G20210A mutation jointly influences plasma prothrombin levels and risk of thrombosis [J]. Blood, 2000, 95 (8): 2780-2785.